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Patricio Godoy
Patricio Godoy
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Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating …
P Godoy, NJ Hewitt, U Albrecht, ME Andersen, N Ansari, S Bhattacharya, ...
Archives of toxicology 87, 1315-1530, 2013
13792013
Hepatocyte-specific Smad7 expression attenuates TGF-β–mediated fibrogenesis and protects against liver damage
S Dooley, J Hamzavi, L Ciuclan, P Godoy, I Ilkavets, S Ehnert, ...
Gastroenterology 135 (2), 642-659. e46, 2008
3402008
Adverse outcome pathways: opportunities, limitations and open questions
M Leist, A Ghallab, R Graepel, R Marchan, R Hassan, SH Bennekou, ...
Archives of Toxicology 91, 3477-3505, 2017
3202017
Extracellular matrix modulates sensitivity of hepatocytes to fibroblastoid dedifferentiation and transforming growth factor β–induced apoptosis
P Godoy, JG Hengstler, I Ilkavets, C Meyer, A Bachmann, A Müller, ...
Hepatology 49 (6), 2031-2043, 2009
2932009
TGF-β/Smad signaling in the injured liver
K Breitkopf, P Godoy, L Ciuclan, MV Singer, S Dooley
Zeitschrift für Gastroenterologie 44 (01), 57-66, 2006
2932006
Gene networks and transcription factor motifs defining the differentiation of stem cells into hepatocyte-like cells
P Godoy, W Schmidt-Heck, K Natarajan, B Lucendo-Villarin, D Szkolnicka, ...
Journal of Hepatology 63 (4), 934-942, 2015
1912015
The etiology of liver damage imparts cytokines transforming growth factor β1 or interleukin‐13 as driving forces in fibrogenesis
HL Weng, Y Liu, JL Chen, T Huang, LJ Xu, P Godoy, JH Hu, C Zhou, ...
Hepatology 50 (1), 230-243, 2009
1662009
Recombinant laminins drive the differentiation and self-organization of hESC-derived hepatocytes
K Cameron, R Tan, W Schmidt-Heck, G Campos, MJ Lyall, Y Wang, ...
Stem cell reports 5 (6), 1250-1262, 2015
1542015
Profibrogenic transforming growth factor‐β/activin receptor–like kinase 5 signaling via connective tissue growth factor expression in hepatocytes
HL Weng, L Ciuclan, Y Liu, J Hamzavi, P Godoy, H Gaitantzi, S Kanzler, ...
Hepatology 46 (4), 1257-1270, 2007
1542007
Primary mouse hepatocytes for systems biology approaches: a standardized in vitro system for modelling of signal transduction pathways
U Klingmüller, A Bauer, S Bohl, PJ Nickel, K Breitkopf, S Dooley, ...
IEE Proceedings-Systems Biology 153 (6), 433-447, 2006
1532006
Toxicogenomics directory of chemically exposed human hepatocytes
M Grinberg, RM Stöber, K Edlund, E Rempel, P Godoy, R Reif, A Widera, ...
Archives of toxicology 88, 2261-2287, 2014
1492014
Protocols for staining of bile canalicular and sinusoidal networks of human, mouse and pig livers, three-dimensional reconstruction and quantification of tissue …
S Hammad, S Hoehme, A Friebel, I von Recklinghausen, A Othman, ...
Archives of toxicology 88, 1161-1183, 2014
1482014
Interactome screening identifies the ER luminal chaperone Hsp47 as a regulator of the unfolded protein response transducer IRE1α
D Sepulveda, D Rojas-Rivera, DA Rodríguez, J Groenendyk, A Köhler, ...
Molecular cell 69 (2), 238-252. e7, 2018
1462018
The network formation assay: a spatially standardized neurite outgrowth analytical display for neurotoxicity screening
JP Frimat, J Sisnaiske, S Subbiah, H Menne, P Godoy, P Lampen, M Leist, ...
Lab on a Chip 10 (6), 701-709, 2010
1342010
Transcription factors ETF, E2F, and SP‐1 are involved in cytokine‐independent proliferation of murine hepatocytes
S Zellmer, W Schmidt‐Heck, P Godoy, H Weng, C Meyer, T Lehmann, ...
Hepatology 52 (6), 2127-2136, 2010
1262010
Model-guided identification of a therapeutic strategy to reduce hyperammonemia in liver diseases
A Ghallab, G Cellière, SG Henkel, D Driesch, S Hoehme, U Hofmann, ...
Journal of hepatology 64 (4), 860-871, 2016
1152016
Gene network activity in cultivated primary hepatocytes is highly similar to diseased mammalian liver tissue
P Godoy, A Widera, W Schmidt-Heck, G Campos, C Meyer, C Cadenas, ...
Archives of toxicology 90, 2513-2529, 2016
1082016
Bile microinfarcts in cholestasis are initiated by rupture of the apical hepatocyte membrane and cause shunting of bile to sinusoidal blood
A Ghallab, U Hofmann, S Sezgin, N Vartak, R Hassan, A Zaza, P Godoy, ...
Hepatology 69 (2), 666-683, 2019
962019
Interferon-inducible guanylate binding protein (GBP2) is associated with better prognosis in breast cancer and indicates an efficient T cell response
P Godoy, C Cadenas, B Hellwig, R Marchan, J Stewart, R Reif, M Lohr, ...
Breast Cancer 21, 491-499, 2014
962014
Human hepatocytes: isolation, culture, and quality procedures
D Knobeloch, S Ehnert, L Schyschka, P Büchler, M Schoenberg, J Kleeff, ...
Human cell culture protocols, 99-120, 2012
832012
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