Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease LTJ Hickson, LGPL Prata, SA Bobart, TK Evans, N Giorgadze, SK Hashmi, ... EBioMedicine 47, 446-456, 2019 | 868* | 2019 |
Obesity-induced cellular senescence drives anxiety and impairs neurogenesis M Ogrodnik, YI Zhu, LGP Langhi, T Tchkonia, P Krüger, E Fielder, ... Cell metabolism 29 (5), 1061-1077. e8, 2019 | 418 | 2019 |
Length‐independent telomere damage drives post‐mitotic cardiomyocyte senescence R Anderson, A Lagnado, D Maggiorani, A Walaszczyk, E Dookun, ... The EMBO journal 38 (5), e100492, 2019 | 376 | 2019 |
Telomeres and cell senescence-size matters not S Victorelli, JF Passos EBioMedicine 21, 14-20, 2017 | 336 | 2017 |
Whole‐body senescent cell clearance alleviates age‐related brain inflammation and cognitive impairment in mice M Ogrodnik, SA Evans, E Fielder, S Victorelli, P Kruger, H Salmonowicz, ... Aging cell 20 (2), e13296, 2021 | 230 | 2021 |
Pharmacological clearance of senescent cells improves survival and recovery in aged mice following acute myocardial infarction A Walaszczyk, E Dookun, R Redgrave, S Tual‐Chalot, S Victorelli, ... Aging cell 18 (3), e12945, 2019 | 184 | 2019 |
Senescent human melanocytes drive skin ageing via paracrine telomere dysfunction S Victorelli, A Lagnado, J Halim, W Moore, D Talbot, K Barrett, J Chapman, ... The EMBO journal 38 (23), e101982, 2019 | 164 | 2019 |
Neutrophils induce paracrine telomere dysfunction and senescence in ROS‐dependent manner A Lagnado, J Leslie, MH Ruchaud‐Sparagano, S Victorelli, P Hirsova, ... The EMBO journal 40 (9), e106048, 2021 | 118 | 2021 |
Cytoplasmic DNA: sources, sensing, and role in aging and disease KN Miller, SG Victorelli, H Salmonowicz, N Dasgupta, T Liu, JF Passos, ... Cell 184 (22), 5506-5526, 2021 | 111 | 2021 |
Apoptotic stress causes mtDNA release during senescence and drives the SASP S Victorelli, H Salmonowicz, J Chapman, H Martini, MG Vizioli, JS Riley, ... Nature 622 (7983), 627-636, 2023 | 67 | 2023 |
Reactive oxygen species detection in senescent cells S Victorelli, JF Passos Cellular Senescence: Methods and Protocols, 21-29, 2019 | 43 | 2019 |
Telomere dysfunction and senescence-associated pathways in bronchiectasis J Birch, S Victorelli, D Rahmatika, RK Anderson, K Jiwa, E Moisey, ... American journal of respiratory and critical care medicine 193 (8), 929-932, 2016 | 38 | 2016 |
Spatial mapping of cellular senescence: emerging challenges and opportunities AU Gurkar, AA Gerencser, AL Mora, AC Nelson, AR Zhang, AB Lagnado, ... Nature aging 3 (7), 776-790, 2023 | 23 | 2023 |
Telomeres and cell senescence-size matters not. EBioMedicine. 2017; 21: 14–20 S Victorelli, JF Passos Original report and review on role of persistence of DNA damage in telomeres …, 0 | 21 | |
Telomeres: beacons of autocrine and paracrine DNA damage during skin aging S Victorelli, JF Passos Cell Cycle 19 (5), 532-540, 2020 | 10 | 2020 |
Toll-like receptor 2 orchestrates a tumor suppressor response in non-small cell lung cancer FR Millar, A Pennycuick, M Muir, A Quintanilla, P Hari, E Freyer, P Gautier, ... Cell reports 41 (6), 2022 | 7 | 2022 |
Antigenotoxic and antimutagenic effects of glutamine supplementation on mice treated with cisplatin JR Pesarini, SG Victorelli, AP Vicentini, LK Ferreira, MO Mauro, R Matuo, ... Genetics and Molecular Research 13 (3), 4820-4830, 2014 | 7 | 2014 |
Anti–cholestatic therapy with obeticholic acid improves short-term memory in bile duct–ligated mice LMV Gee, B Barron-Millar, J Leslie, C Richardson, MYW Zaki, S Luli, ... The American Journal of Pathology 193 (1), 11-26, 2023 | 6 | 2023 |
Length-independent telomere damage drives cardiomyocyte senescence R Anderson, A Lagnado, D Maggiorani, A Walaszczyk, E Dookun, ... bioRxiv, 394809, 2018 | 6 | 2018 |
3D bioprinting—a model for skin aging RB Ansaf, R Ziebart, H Gudapati, RM Simoes Torigoe, S Victorelli, ... Regenerative Biomaterials 10, 2023 | 5 | 2023 |