Modesto Orozco
Modesto Orozco
Professor of Biochemistry, Universtity of Barcelona
Verified email at irbbarcelona.org
TitleCited byYear
The tomato genome sequence provides insights into fleshy fruit evolution
Tomato Genome Consortium
Nature 485 (7400), 635, 2012
18622012
Refinement of the AMBER force field for nucleic acids: improving the description of α/γ conformers
A Pérez, I Marchán, D Svozil, J Sponer, TE Cheatham III, CA Laughton, ...
Biophysical journal 92 (11), 3817-3829, 2007
16322007
Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia
XS Puente, M Pinyol, V Quesada, L Conde, GR Ordóñez, N Villamor, ...
Nature 475 (7354), 101, 2011
13182011
Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia
V Quesada, L Conde, N Villamor, GR Ordóñez, P Jares, L Bassaganyas, ...
Nature genetics 44 (1), 47, 2012
8382012
Theoretical methods for the description of the solvent effect in biomolecular systems
M Orozco, FJ Luque
Chemical Reviews 100 (11), 4187-4226, 2000
6192000
Perspective on “Electrostatic interactions of a solute with a continuum. A direct utilization of ab initio molecular potentials for the prevision of solvent effects”
FJ Luque, JM López, M Orozco
Theoretical Chemistry Accounts 103 (3-4), 343-345, 2000
5322000
PMUT: a web-based tool for the annotation of pathological mutations on proteins
C Ferrer-Costa, JL Gelpí, L Zamakola, I Parraga, X De La Cruz, M Orozco
Bioinformatics 21 (14), 3176-3178, 2005
4632005
Non-coding recurrent mutations in chronic lymphocytic leukaemia
XS Puente, S Beà, R Valdés-Mas, N Villamor, J Gutiérrez-Abril, ...
Nature 526 (7574), 519, 2015
4262015
Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukemia
M Kulis, S Heath, M Bibikova, AC Queirós, A Navarro, G Clot, ...
Nature genetics 44 (11), 1236, 2012
3982012
Tautomerism and protonation of guanine and cytosine. Implications in the formation of hydrogen-bonded complexes
C Colominas, FJ Luque, M Orozco
Journal of the American Chemical Society 118 (29), 6811-6821, 1996
3171996
A systematic molecular dynamics study of nearest-neighbor effects on base pair and base pair step conformations and fluctuations in B-DNA
R Lavery, K Zakrzewska, D Beveridge, TC Bishop, DA Case, ...
Nucleic acids research 38 (1), 299-313, 2009
2802009
Is polarization important in cation-π interactions?
E Cubero, FJ Luque, M Orozco
Proceedings of the National Academy of Sciences 95 (11), 5976-5980, 1998
2801998
Target flexibility: an emerging consideration in drug discovery and design
P Cozzini, GE Kellogg, F Spyrakis, DJ Abraham, G Costantino, A Emerson, ...
Journal of medicinal chemistry 51 (20), 6237-6255, 2008
2702008
Performance of molecular mechanics force fields for RNA simulations: stability of UUCG and GNRA hairpins
P Banás, D Hollas, M Zgarbová, P Jurecka, M Orozco, TE Cheatham III, ...
Journal of Chemical Theory and Computation 6 (12), 3836-3849, 2010
2502010
Dynamics of B-DNA on the microsecond time scale
A Pérez, FJ Luque, M Orozco
Journal of the American Chemical Society 129 (47), 14739-14745, 2007
2442007
Hydrogen bond versus anti-hydrogen bond: a comparative analysis based on the electron density topology
E Cubero, M Orozco, P Hobza, FJ Luque
The Journal of Physical Chemistry A 103 (32), 6394-6401, 1999
2371999
Parmbsc1: a refined force field for DNA simulations
I Ivani, PD Dans, A Noy, A Pérez, I Faustino, A Hospital, J Walther, ...
Nature methods 13 (1), 55, 2016
2212016
Nature of base stacking: reference quantum‐chemical stacking energies in ten unique B‐DNA base‐pair steps
J Šponer, P Jurečka, I Marchan, FJ Luque, M Orozco, P Hobza
Chemistry–A European Journal 12 (10), 2854-2865, 2006
2192006
Characterization of disease-associated single amino acid polymorphisms in terms of sequence and structure properties
C Ferrer-Costa, M Orozco, X de la Cruz
Journal of molecular biology 315 (4), 771-786, 2002
2172002
Design, synthesis, and biological evaluation of dual binding site acetylcholinesterase inhibitors: new disease-modifying agents for Alzheimer's disease
P Munoz-Ruiz, L Rubio, E García-Palomero, I Dorronsoro, ...
Journal of medicinal chemistry 48 (23), 7223-7233, 2005
1962005
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