Follow
Alexis Courbet
Alexis Courbet
Research associate, HHMI - The Baker Lab - Institute for Protein Design, University of Washington
Verified email at uw.edu
Title
Cited by
Cited by
Year
Robust deep learning–based protein sequence design using ProteinMPNN
J Dauparas, I Anishchenko, N Bennett, H Bai, RJ Ragotte, LF Milles, ...
Science 378 (6615), 49-56, 2022
5382022
De novo design of protein structure and function with RFdiffusion
JL Watson, D Juergens, NR Bennett, BL Trippe, J Yim, HE Eisenach, ...
Nature 620 (7976), 1089-1100, 2023
3232023
Detection of pathological biomarkers in human clinical samples via amplifying genetic switches and logic gates
A Courbet, D Endy, E Renard, F Molina, J Bonnet
Science translational medicine 7 (289), 289ra83-289ra83, 2015
2572015
Broadly applicable and accurate protein design by integrating structure prediction networks and diffusion generative models
JL Watson, D Juergens, NR Bennett, BL Trippe, J Yim, HE Eisenach, ...
BioRxiv, 2022.12. 09.519842, 2022
1622022
Hallucinating symmetric protein assemblies
BIM Wicky, LF Milles, A Courbet, RJ Ragotte, J Dauparas, E Kinfu, S Tipps, ...
Science 378 (6615), 56-61, 2022
1192022
Design of multi-scale protein complexes by hierarchical building block fusion
Y Hsia, R Mout, W Sheffler, NI Edman, I Vulovic, YJ Park, RL Redler, ...
Nature Communications 12 (1), 2294, 2021
562021
Top-down design of protein architectures with reinforcement learning
ID Lutz, S Wang, C Norn, A Courbet, AJ Borst, YT Zhao, A Dosey, L Cao, ...
Science 380 (6642), 266-273, 2023
432023
Computational design of mechanically coupled axle-rotor protein assemblies
A Courbet, J Hansen, Y Hsia, N Bethel, YJ Park, C Xu, A Moyer, ...
Science 376 (6591), 383-390, 2022
432022
Reconfigurable asymmetric protein assemblies through implicit negative design
DD Sahtoe, F Praetorius, A Courbet, Y Hsia, BIM Wicky, NI Edman, ...
Science 375 (6578), eabj7662, 2022
432022
Bringing next‐generation diagnostics to the clinic through synthetic biology
A Courbet, E Renard, F Molina
EMBO molecular medicine 8 (9), 987-991, 2016
352016
Computer‐aided biochemical programming of synthetic microreactors as diagnostic devices
A Courbet, P Amar, F Fages, E Renard, F Molina
Molecular Systems Biology 14 (4), e7845, 2018
332018
Generation of ordered protein assemblies using rigid three-body fusion
I Vulovic, Q Yao, YJ Park, A Courbet, A Norris, F Busch, A Sahasrabuddhe, ...
Proceedings of the National Academy of Sciences 118 (23), e2015037118, 2021
322021
Imidazoquinoxaline anticancer derivatives and imiquimod interact with tubulin: Characterization of molecular microtubule inhibiting mechanisms in correlation with cytotoxicity
A Courbet, N Bec, C Constant, C Larroque, M Pugniere, S El Messaoudi, ...
PLoS One 12 (8), e0182022, 2017
272017
Hierarchical design of multi-scale protein complexes by combinatorial assembly of oligomeric helical bundle and repeat protein building blocks
Y Hsia, R Mout, W Sheffler, NI Edman, I Vulovic, YJ Park, RL Redler, ...
bioRxiv, 2020.07. 27.221333, 2020
82020
Computing with synthetic protocells
A Courbet, F Molina, P Amar
Acta biotheoretica 63 (3), 309-323, 2015
82015
Accurate computational design of three-dimensional protein crystals
Z Li, S Wang, U Nattermann, AK Bera, AJ Borst, MY Yaman, MJ Bick, ...
Nature Materials 22 (12), 1556-1563, 2023
62023
Self-assembly–based posttranslational protein oscillators
O Kimchi, CP Goodrich, A Courbet, AI Curatolo, NB Woodall, D Baker, ...
Science Advances 6 (51), eabc1939, 2020
62020
Hallucination of closed repeat proteins containing central pockets
L An, DR Hicks, D Zorine, J Dauparas, BIM Wicky, LF Milles, A Courbet, ...
Nature Structural & Molecular Biology 30 (11), 1755-1760, 2023
52023
Detection of pathological biomarkers in human clinical samples via amplifying genetic switches and logic gates. Sci Transl Med 7: 289ra83–289ra83
A Courbet, D Endy, E Renard, F Molina, J Bonnet
42015
Accurate computational design of 3D protein crystals
Z Li, S Wang, U Nattermann, AK Bera, AJ Borst, MJ Bick, EC Yang, ...
bioRxiv, 2022.11. 18.517014, 2022
32022
The system can't perform the operation now. Try again later.
Articles 1–20