Lary Walker
Lary Walker
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Self-propagation of pathogenic protein aggregates in neurodegenerative diseases
M Jucker, LC Walker
Nature 501 (7465), 45-51, 2013
Exogenous induction of cerebral ß-amyloidogenesis is governed by agent and host
M Meyer-Luehmann, J Coomaraswamy, T Bolmont, S Kaeser, C Schaefer, ...
Science 313 (5794), 1781-1784, 2006
Pathogenic protein seeding in Alzheimer disease and other neurodegenerative disorders
M Jucker, LC Walker
Annals of neurology 70 (4), 532-540, 2011
Peripherally applied Aβ-containing inoculates induce cerebral β-amyloidosis
YS Eisele, U Obermüller, G Heilbronner, F Baumann, SA Kaeser, ...
Science 330 (6006), 980-982, 2010
Evidence for seeding of β-amyloid by intracerebral infusion of Alzheimer brain extracts in β-amyloid precursor protein-transgenic mice
MD Kane, WJ Lipinski, MJ Callahan, F Bian, RA Durham, RD Schwarz, ...
Journal of Neuroscience 20 (10), 3606-3611, 2000
Deposition of Alzheimer's β-amyloid is inversely correlated with P-glycoprotein expression in the brains of elderly non-demented humans
S Vogelgesang, I Cascorbi, E Schroeder, J Pahnke, HK Kroemer, ...
Pharmacogenetics and Genomics 12 (7), 535-541, 2002
Age‐dependent impairment of mitochondrial function in primate brain
AC Bowling, EM Mutisya, LC Walker, DL Price, LC Cork, MH Beal
Journal of neurochemistry 60 (5), 1964-1967, 1993
Aged monkeys exhibit behavioral deficits indicative of widespread cerebral dysfunction
J Bachevalier, LS Landis, LC Walker, M Brickson, M Mishkin, DL Price, ...
Neurobiology of aging 12 (2), 99-111, 1991
Augmented senile plaque load in aged female β-amyloid precursor protein-transgenic mice
MJ Callahan, WJ Lipinski, F Bian, RA Durham, A Pack, LC Walker
The American journal of pathology 158 (3), 1173-1177, 2001
Induction of cerebral β-amyloidosis: intracerebral versus systemic Aβ inoculation
YS Eisele, T Bolmont, M Heikenwalder, F Langer, LH Jacobson, ZX Yan, ...
Proceedings of the National Academy of Sciences 106 (31), 12926-12931, 2009
Loss of NMDA, but not GABA-A, binding in the brains of aged rats and monkeys
GL Wenk, LC Walker, DL Price, LC Cork
Neurobiology of aging 12 (2), 93-98, 1991
Accelerated glial reactivity to stroke in aged rats correlates with reduced functional recovery
I Badan, B Buchhold, A Hamm, M Gratz, LC Walker, D Platt, C Kessler, ...
Journal of Cerebral Blood Flow & Metabolism 23 (7), 845-854, 2003
Neurodegenerative diseases: expanding the prion concept
LC Walker, M Jucker
Annual review of neuroscience 38, 87-103, 2015
Amyloid-associated neuron loss and gliogenesis in the neocortex of amyloid precursor protein transgenic mice
L Bondolfi, M Calhoun, F Ermini, HG Kuhn, KH Wiederhold, L Walker, ...
Journal of Neuroscience 22 (2), 515-522, 2002
MDR1‐P‐Glycoprotein (ABCB1) Mediates Transport of Alzheimer’s Amyloid‐β Peptides—Implications for the Mechanisms of Aβ Clearance at the Blood–Brain Barrier
D Kuhnke, G Jedlitschky, M Grube, M Krohn, M Jucker, I Mosyagin, ...
Brain Pathology 17 (4), 347-353, 2007
Soluble Aβ seeds are potent inducers of cerebral β-amyloid deposition
F Langer, YS Eisele, SK Fritschi, M Staufenbiel, LC Walker, M Jucker
Journal of Neuroscience 31 (41), 14488-14495, 2011
Mechanisms of protein seeding in neurodegenerative diseases
LC Walker, MI Diamond, KE Duff, BT Hyman
JAMA neurology 70 (3), 304-310, 2013
Abnormalities of the nucleus basalis in Down's syndrome
MF Casanova, LC Walker, PJ Whitehouse, DL Price
Annals of Neurology: Official Journal of the American Neurological …, 1985
Loss of pedunculopontine neurons in progressive supranuclear palsy
RM Zweig, PJ Whitehouse, MF Casanova, LC Walker, WR Jankel, ...
Annals of neurology 22 (1), 18-25, 1987
Propagation and spread of pathogenic protein assemblies in neurodegenerative diseases
M Jucker, LC Walker
Nature neuroscience 21 (10), 1341-1349, 2018
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