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Tomoharu Kuboyama
Tomoharu Kuboyama
Associate Professor of Daiichi University of Pharmacy
Bestätigte E-Mail-Adresse bei daiichi-cps.ac.jp
Titel
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Jahr
Neuritic regeneration and synaptic reconstruction induced by withanolide A
T Kuboyama, C Tohda, K Komatsu
British journal of pharmacology 144 (7), 961-971, 2005
3922005
Search for natural products related to regeneration of the neuronal network
C Tohda, T Kuboyama, K Komatsu
Neurosignals 14 (1-2), 34-45, 2005
3412005
Withanolide derivatives from the roots of Withania somnifera and their neurite outgrowth activities
J Zhao, N Nakamura, M Hattori, T Kuboyama, C Tohda, K Komatsu
Chemical and pharmaceutical bulletin 50 (6), 760-765, 2002
2362002
Withanoside IV and its active metabolite, sominone, attenuate Aβ (25–35)‐induced neurodegeneration
T Kuboyama, C Tohda, K Komatsu
European Journal of Neuroscience 23 (6), 1417-1426, 2006
1882006
Diosgenin is an exogenous activator of 1, 25D3-MARRS/Pdia3/ERp57 and improves Alzheimer's disease pathologies in 5XFAD mice
C Tohda, T Urano, M Umezaki, I Nemere, T Kuboyama
Scientific reports 2 (1), 1-11, 2012
1822012
Axon-or dendrite-predominant outgrowth induced by constituents from Ashwagandha
T Kuboyama, C Tohda, J Zhao, N Nakamura, M Hattori, K Komatsu
Neuroreport 13 (14), 1715-1720, 2002
1552002
Effects of Ashwagandha (roots of Withania somnifera) on neurodegenerative diseases
T Kuboyama, C Tohda, K Komatsu
Biological and Pharmaceutical Bulletin 37 (6), 892-897, 2014
1432014
Dendrite extension by methanol extract of Ashwagandha (roots of Withania somnifera) in SK-N-SH cells
C Tohda, T Kuboyama, K Komatsu
Neuroreport 11 (9), 1981-1985, 2000
1402000
Current and future therapeutic strategies for functional repair of spinal cord injury
C Tohda, T Kuboyama
Pharmacology & therapeutics 132 (1), 57-71, 2011
1182011
A systematic strategy for discovering a therapeutic drug for Alzheimer’s disease and its target molecule
Z Yang, T Kuboyama, C Tohda
Frontiers in pharmacology 8, 273886, 2017
902017
A novel compound, denosomin, ameliorates spinal cord injury via axonal growth associated with astrocyte‐secreted vimentin
K Teshigawara, T Kuboyama, M Shigyo, A Nagata, K Sugimoto, ...
British journal of pharmacology 168 (4), 903-919, 2013
712013
Extracellular vimentin interacts with insulin-like growth factor 1 receptor to promote axonal growth
M Shigyo, T Kuboyama, Y Sawai, M Tada-Umezaki, C Tohda
Scientific reports 5 (1), 12055, 2015
652015
Naringenin promotes microglial M2 polarization and Aβ degradation enzyme expression
Z Yang, T Kuboyama, C Tohda
Phytotherapy research 33 (4), 1114-1121, 2019
582019
HDAC3 inhibition ameliorates spinal cord injury by immunomodulation
T Kuboyama, S Wahane, Y Huang, X Zhou, JK Wong, A Koemeter-Cox, ...
Scientific reports 7 (1), 8641, 2017
512017
Kamikihi-to (KKT) rescues axonal and synaptic degeneration associated with memory impairment in a mouse model of Alzheimer's disease, 5XFAD
C Tohda, R Nakada, T Urano, A Okonogi, T Kuboyama
International Journal of Neuroscience 121 (12), 641-648, 2011
492011
Polygalae radix extract prevents axonal degeneration and memory deficits in a transgenic mouse model of Alzheimer’s disease
T Kuboyama, K Hirotsu, T Arai, H Yamasaki, C Tohda
Frontiers in Pharmacology 8, 805, 2017
392017
Scientific basis for the anti-dementia drugs of constituents from Ashwagandha (Withania somnifera)
C Tohda, K Komatsu, T Kuboyama
J Tad Med 22, 176-182, 2005
382005
Active Constituents from Drynaria fortunei Rhizomes on the Attenuation of Aβ25–35-Induced Axonal Atrophy
ZY Yang, T Kuboyama, K Kazuma, K Konno, C Tohda
Journal of natural products 78 (9), 2297-2300, 2015
372015
A novel Rac1-GSPT1 signaling pathway controls astrogliosis following central nervous system injury
T Ishii, T Ueyama, M Shigyo, M Kohta, T Kondoh, T Kuboyama, T Uebi, ...
Journal of Biological Chemistry 292 (4), 1240-1250, 2017
362017
Trigonelline recovers memory function in Alzheimer’s disease model mice: evidence of brain penetration and target molecule
MM Farid, X Yang, T Kuboyama, C Tohda
Scientific Reports 10 (1), 16424, 2020
342020
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