Michaela Wenzel
Michaela Wenzel
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Daptomycin inhibits cell envelope synthesis by interfering with fluid membrane microdomains
A Müller, M Wenzel, H Strahl, F Grein, TNV Saaki, B Kohl, T Siersma, ...
Proceedings of the National Academy of Sciences 113 (45), E7077-E7086, 2016
Small cationic antimicrobial peptides delocalize peripheral membrane proteins
M Wenzel, AI Chiriac, A Otto, D Zweytick, C May, C Schumacher, R Gust, ...
Proceedings of the National Academy of Sciences 111 (14), E1409-E1418, 2014
Analysis of the mechanism of action of potent antibacterial hetero-tri-organometallic compounds: a structurally new class of antibiotics
M Wenzel, M Patra, CHR Senges, I Ott, JJ Stepanek, A Pinto, P Prochnow, ...
ACS chemical biology 8 (7), 1442-1450, 2013
Synthesis and biological evaluation of ferrocene-containing bioorganometallics inspired by the antibiotic platensimycin lead structure
M Patra, G Gasser, M Wenzel, K Merz, JE Bandow, N Metzler-Nolte
Organometallics 29 (19), 4312-4319, 2010
Proteomic response of Bacillus subtilis to lantibiotics reflects differences in interaction with the cytoplasmic membrane
M Wenzel, B Kohl, D Münch, N Raatschen, HB Albada, L Hamoen, ...
Antimicrobial agents and chemotherapy 56 (11), 5749-5757, 2012
Antimicrobial peptide cWFW kills by combining lipid phase separation with autolysis
K Scheinpflug, M Wenzel, O Krylova, JE Bandow, M Dathe, H Strahl
Scientific reports 7 (1), 1-15, 2017
The lantibiotic NAI-107 binds to bactoprenol-bound cell wall precursors and impairs membrane functions
D Münch, A Müller, T Schneider, B Kohl, M Wenzel, JE Bandow, S Maffioli, ...
Journal of Biological Chemistry 289 (17), 12063-12076, 2014
Modulating the activity of short arginine-tryptophan containing antibacterial peptides with N-terminal metallocenoyl groups
HB Albada, AI Chiriac, M Wenzel, M Penkova, JE Bandow, HG Sahl, ...
Beilstein journal of organic chemistry 8 (1), 1753-1764, 2012
Proteomic signature of fatty acid biosynthesis inhibition available for in vivo mechanism-of-action studies
M Wenzel, M Patra, D Albrecht, DYK Chen, KC Nicolaou, N Metzler-Nolte, ...
Antimicrobial agents and chemotherapy 55 (6), 2590-2596, 2011
Proteomic signatures in antibiotic research
M Wenzel, JE Bandow
Proteomics 11 (15), 3256-3268, 2011
The multifaceted antibacterial mechanisms of the pioneering peptide antibiotics tyrocidine and gramicidin S
M Wenzel, M Rautenbach, JA Vosloo, T Siersma, CHM Aisenbrey, ...
MBio 9 (5), e00802-18, 2018
An organometallic structure-activity relationship study reveals the essential role of a Re (CO) 3 moiety in the activity against gram-positive pathogens including MRSA
M Patra, M Wenzel, P Prochnow, V Pierroz, G Gasser, JE Bandow, ...
Chemical science 6 (1), 214-224, 2015
Multitarget approaches against multiresistant superbugs
DA Gray, M Wenzel
ACS Infectious Diseases 6 (6), 1346-1365, 2020
More than a pore: a current perspective on the in vivo mode of action of the lipopeptide antibiotic daptomycin
DA Gray, M Wenzel
Antibiotics 9 (1), 17, 2020
Sandwich and half-sandwich derivatives of Platensimycin: Synthesis and biological evaluation
M Patra, G Gasser, M Wenzel, K Merz, JE Bandow, N Metzler-Nolte
Organometallics 31 (16), 5760-5771, 2012
The novel antibiotic rhodomyrtone traps membrane proteins in vesicles with increased fluidity
D Saeloh, V Tipmanee, KK Jim, MP Dekker, W Bitter, ...
PLoS pathogens 14 (2), e1006876, 2018
Bactericidal activity of amphipathic cationic antimicrobial peptides involves altering the membrane fluidity when interacting with the phospholipid bilayer
S Omardien, JW Drijfhout, FM Vaz, M Wenzel, LW Hamoen, SAJ Zaat, ...
Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (11), 2404-2415, 2018
Influence of lipidation on the mode of action of a small RW-rich antimicrobial peptide
M Wenzel, P Schriek, P Prochnow, HB Albada, N Metzler-Nolte, ...
Biochimica et Biophysica Acta (BBA)-Biomembranes 1858 (5), 1004-1011, 2016
Antimicrobial Peptides from the Aurein Family Form Ion‐Selective Pores in Bacillus subtilis
M Wenzel, CHR Senges, J Zhang, S Suleman, M Nguyen, P Kumar, ...
ChemBioChem 16 (7), 1101-1108, 2015
Assessing membrane fluidity and visualizing fluid membrane domains in bacteria using fluorescent membrane dyes
M Wenzel, NOE Vischer, H Strahl, LW Hamoen
Bio-protocol 8 (20), e3063-e3063, 2018
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