Kevin T. Love
Kevin T. Love
Director of Business Development and Operations, Arsia Therapeutics
Bestätigte E-Mail-Adresse bei arsiarx.com
TitelZitiert vonJahr
Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery
H Lee, AKR Lytton-Jean, Y Chen, KT Love, AI Park, ED Karagiannis, ...
Nature nanotechnology 7 (6), 389, 2012
6702012
Lipid-like materials for low-dose, in vivo gene silencing
KT Love, KP Mahon, CG Levins, KA Whitehead, W Querbes, JR Dorkin, ...
Proceedings of the National Academy of Sciences 107 (5), 1864-1869, 2010
6572010
Therapeutic siRNA silencing in inflammatory monocytes in mice
F Leuschner, P Dutta, R Gorbatov, TI Novobrantseva, JS Donahoe, ...
Nature biotechnology 29 (11), 1005, 2011
5242011
Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling
G Sahay, W Querbes, C Alabi, A Eltoukhy, S Sarkar, C Zurenko, ...
Nature biotechnology 31 (7), 653, 2013
3972013
Gold, poly (β-amino ester) nanoparticles for small interfering RNA delivery
JS Lee, JJ Green, KT Love, J Sunshine, R Langer, DG Anderson
Nano letters 9 (6), 2402-2406, 2009
2842009
Rapid discovery of potent siRNA-containing lipid nanoparticles enabled by controlled microfluidic formulation
D Chen, KT Love, Y Chen, AA Eltoukhy, C Kastrup, G Sahay, A Jeon, ...
Journal of the American Chemical Society 134 (16), 6948-6951, 2012
2372012
Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates
Y Dong, KT Love, JR Dorkin, S Sirirungruang, Y Zhang, D Chen, ...
Proceedings of the National Academy of Sciences 111 (11), 3955-3960, 2014
2352014
Combinatorial synthesis of chemically diverse core-shell nanoparticles for intracellular delivery
DJ Siegwart, KA Whitehead, L Nuhn, G Sahay, H Cheng, S Jiang, M Ma, ...
Proceedings of the National Academy of Sciences 108 (32), 12996-13001, 2011
1772011
BCL2A1 is a lineage-specific antiapoptotic melanoma oncogene that confers resistance to BRAF inhibition
R Haq, S Yokoyama, EB Hawryluk, GB Jönsson, DT Frederick, K McHenry, ...
Proceedings of the National Academy of Sciences 110 (11), 4321-4326, 2013
1682013
Lipidoid-coated iron oxide nanoparticles for efficient DNA and siRNA delivery
S Jiang, AA Eltoukhy, KT Love, R Langer, DG Anderson
Nano letters 13 (3), 1059-1064, 2013
1562013
Claudin-3 gene silencing with siRNA suppresses ovarian tumor growth and metastasis
YH Huang, Y Bao, W Peng, M Goldberg, K Love, DA Bumcrot, G Cole, ...
Proceedings of the National Academy of Sciences 106 (9), 3426-3430, 2009
1312009
Aminoalcohol lipidoids and uses thereof
KP Mahon, KT Love, CG Levins, KA Whitehead, RS Langer, DG Anderson
US Patent 8,450,298, 2013
1182013
Systemic RNAi-mediated gene silencing in nonhuman primate and rodent myeloid cells
TI Novobrantseva, A Borodovsky, J Wong, B Klebanov, M Zafari, K Yucius, ...
Molecular Therapy-Nucleic Acids 1, e4, 2012
972012
Multiparametric approach for the evaluation of lipid nanoparticles for siRNA delivery
CA Alabi, KT Love, G Sahay, H Yin, KM Luly, R Langer, DG Anderson
Proceedings of the National Academy of Sciences 110 (32), 12881-12886, 2013
822013
Lipid-derived nanoparticles for immunostimulatory RNA adjuvant delivery
DN Nguyen, KP Mahon, G Chikh, P Kim, H Chung, AP Vicari, KT Love, ...
Proceedings of the National Academy of Sciences 109 (14), E797-E803, 2012
822012
Combinatorial approach to determine functional group effects on lipidoid-mediated siRNA delivery
KP Mahon, KT Love, KA Whitehead, J Qin, A Akinc, E Leshchiner, ...
Bioconjugate chemistry 21 (8), 1448-1454, 2010
642010
Aminoalcohol lipidoids and uses thereof
KP Mahon, KT Love, CG Levins, KA Whitehead, RS Langer, DG Anderson
US Patent 8,969,353, 2015
622015
FRET-labeled siRNA probes for tracking assembly and disassembly of siRNA nanocomplexes
CA Alabi, KT Love, G Sahay, T Stutzman, WT Young, R Langer, ...
ACS nano 6 (7), 6133-6141, 2012
562012
Amino acid-, peptide-and polypeptide-lipids, isomers, compositions, and uses thereof
Y Dong, KT Love, RS Langer, DG Anderson, D Chen, Y Chen, AJ Vegas, ...
US Patent 9,512,073, 2016
542016
Synergistic silencing: combinations of lipid-like materials for efficacious siRNA delivery
KA Whitehead, G Sahay, GZ Li, KT Love, CA Alabi, M Ma, C Zurenko, ...
Molecular Therapy 19 (9), 1688-1694, 2011
532011
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