Four histone variants mark the boundaries of polycistronic transcription units in Trypanosoma brucei TN Siegel, DR Hekstra, LE Kemp, LM Figueiredo, JE Lowell, D Fenyo, ... Genes & development 23 (9), 1063-1076, 2009 | 425 | 2009 |
Genome-wide analysis of mRNA abundance in two life-cycle stages of Trypanosoma brucei and identification of splicing and polyadenylation sites TN Siegel, DR Hekstra, X Wang, S Dewell, GAM Cross Nucleic acids research 38 (15), 4946-4957, 2010 | 363 | 2010 |
Evidence for a shared nuclear pore complex architecture that is conserved from the last common eukaryotic ancestor JA DeGrasse, KN DuBois, D Devos, TN Siegel, A Sali, MC Field, MP Rout, ... Molecular & Cellular Proteomics 8 (9), 2119-2130, 2009 | 233 | 2009 |
Genome organization and DNA accessibility control antigenic variation in trypanosomes LSM Müller, RO Cosentino, KU Förstner, J Guizetti, C Wedel, N Kaplan, ... Nature 563 (7729), 121-125, 2018 | 187 | 2018 |
Comparative ribosome profiling reveals extensive translational complexity in different Trypanosoma brucei life cycle stages JJ Vasquez, CC Hon, JT Vanselow, A Schlosser, TN Siegel Nucleic acids research 42 (6), 3623-3637, 2014 | 178 | 2014 |
Strand-specific RNA-Seq reveals widespread and developmentally regulated transcription of natural antisense transcripts in Plasmodium falciparum TN Siegel, CC Hon, Q Zhang, JJ Lopez-Rubio, C Scheidig-Benatar, ... BMC genomics 15, 1-16, 2014 | 112 | 2014 |
Systematic Study of Sequence Motifs for RNA trans Splicing in Trypanosoma brucei TN Siegel, KSW Tan, GAM Cross Molecular and cellular biology 25 (21), 9586-9594, 2005 | 109 | 2005 |
Gene expression in Trypanosoma brucei: lessons from high-throughput RNA sequencing TN Siegel, K Gunasekera, GAM Cross, T Ochsenreiter Trends in parasitology 27 (10), 434-441, 2011 | 108 | 2011 |
Two thymidine hydroxylases differentially regulate the formation of glucosylated DNA at regions flanking polymerase II polycistronic transcription units throughout the genome … LJ Cliffe, TN Siegel, M Marshall, GAM Cross, R Sabatini Nucleic acids research 38 (12), 3923-3935, 2010 | 100 | 2010 |
Histone H3 trimethylated at lysine 4 is enriched at probable transcription start sites in Trypanosoma brucei JR Wright, TN Siegel, GAM Cross Molecular and biochemical parasitology 172 (2), 141-144, 2010 | 98 | 2010 |
Analysis of the Trypanosoma brucei cell cycle by quantitative DAPI imaging TN Siegel, DR Hekstra, GAM Cross Molecular and biochemical parasitology 160 (2), 171-174, 2008 | 98 | 2008 |
Exonuclease-mediated degradation of nascent RNA silences genes linked to severe malaria Q Zhang, TN Siegel, RM Martins, F Wang, J Cao, Q Gao, X Cheng, ... Nature 513 (7518), 431-435, 2014 | 88 | 2014 |
Regulation of transcription termination by glucosylated hydroxymethyluracil, base J, in Leishmania major and Trypanosoma brucei D Reynolds, L Cliffe, KU Förstner, CC Hon, TN Siegel, R Sabatini Nucleic acids research 42 (15), 9717-9729, 2014 | 86 | 2014 |
GT‐rich promoters can drive RNA pol II transcription and deposition of H2A. Z in African trypanosomes C Wedel, KU Förstner, R Derr, TN Siegel The EMBO journal 36 (17), 2581-2594, 2017 | 85 | 2017 |
Two essential MYST‐family proteins display distinct roles in histone H4K10 acetylation and telomeric silencing in trypanosomes T Kawahara, TN Siegel, AK Ingram, S Alsford, GAM Cross, D Horn Molecular microbiology 69 (4), 1054-1068, 2008 | 85 | 2008 |
Novel insights into RNP granules by employing the trypanosome's microtubule skeleton as a molecular sieve M Fritz, J Vanselow, N Sauer, S Lamer, C Goos, TN Siegel, I Subota, ... Nucleic acids research 43 (16), 8013-8032, 2015 | 82 | 2015 |
PfAlbas constitute a new eukaryotic DNA/RNA-binding protein family in malaria parasites A Chêne, SS Vembar, L Rivière, JJ Lopez-Rubio, A Claes, TN Siegel, ... Nucleic acids research 40 (7), 3066-3077, 2012 | 80 | 2012 |
Acetylation of histone H4K4 is cell cycle regulated and mediated by HAT3 in Trypanosoma brucei TN Siegel, T Kawahara, JA DeGrasse, CJ Janzen, D Horn, GAM Cross Molecular microbiology 67 (4), 762-771, 2008 | 70 | 2008 |
Efficient and specific oligo-based depletion of rRNA AJ Kraus, BG Brink, TN Siegel Scientific reports 9 (1), 12281, 2019 | 69 | 2019 |
Noncoding RNAs as emerging regulators of Plasmodium falciparum virulence gene expression SS Vembar, A Scherf, TN Siegel Current opinion in microbiology 20, 153-161, 2014 | 65 | 2014 |