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Rasmus Prætorius Clausen
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Year
Subunit-specific agonist activity at NR2A-, NR2B-, NR2C-, and NR2D-containing N-methyl-D-aspartate glutamate receptors
K Erreger, MT Geballe, A Kristensen, PE Chen, KB Hansen, CJ Lee, ...
Molecular pharmacology 72 (4), 907-920, 2007
2002007
Synaptic and extrasynaptic GABA transporters as targets for anti‐epileptic drugs
KK Madsen, RP Clausen, OM Larsson, P Krogsgaard‐Larsen, ...
Journal of neurochemistry 109, 139-144, 2009
1252009
Inhibitors of histone demethylases
B Lohse, JL Kristensen, LH Kristensen, K Agger, K Helin, M Gajhede, ...
Bioorganic & medicinal chemistry 19 (12), 3625-3636, 2011
1202011
α4βδ GABAA receptors are high-affinity targets for γ-hydroxybutyric acid (GHB)
N Absalom, LF Eghorn, IS Villumsen, N Karim, T Bay, JV Olsen, ...
Proceedings of the National Academy of Sciences 109 (33), 13404-13409, 2012
1082012
Selective inhibitors of GABA uptake: synthesis and molecular pharmacology of 4-N-methylamino-4, 5, 6, 7-tetrahydrobenzo [d] isoxazol-3-ol analogues
RP Clausen, EK Moltzen, J Perregaard, SM Lenz, C Sanchez, E Falch, ...
Bioorganic & medicinal chemistry 13 (3), 895-908, 2005
902005
Structural determinants of agonist efficacy at the glutamate binding site of N-methyl-D-aspartate receptors
KB Hansen, N Tajima, R Risgaard, RE Perszyk, L Jørgensen, KM Vance, ...
Molecular pharmacology 84 (1), 114-127, 2013
832013
Modified Peptides as Potent Inhibitors of the Postsynaptic Density-95/N-Methyl-d-Aspartate Receptor Interaction
A Bach, CN Chi, TB Olsen, SW Pedersen, MU Røder, GF Pang, ...
Journal of medicinal chemistry 51 (20), 6450-6459, 2008
802008
First demonstration of a functional role for central nervous system betaine/γ-aminobutyric acid transporter (mGAT2) based on synergistic anticonvulsant action among inhibitors …
HS White, WP Watson, SL Hansen, S Slough, J Perregaard, A Sarup, ...
Journal of Pharmacology and Experimental Therapeutics 312 (2), 866-874, 2005
782005
Structure-activity relationships of selective GABA uptake inhibitors
S Hog, JR Greenwood, KB Madsen, OM Larsson, B Frolund, ...
Current topics in medicinal chemistry 6 (17), 1861-1882, 2006
752006
Deletion of the betaine–GABA transporter (BGT1; slc6a12) gene does not affect seizure thresholds of adult mice
AC Lehre, NM Rowley, Y Zhou, S Holmseth, C Guo, T Holen, R Hua, ...
Epilepsy research 95 (1-2), 70-81, 2011
712011
Structural proof of a dimeric positive modulator bridging two identical AMPA receptor-binding sites
BH Kaae, K Harpsøe, JS Kastrup, AC Sanz, DS Pickering, B Metzler, ...
Chemistry & biology 14 (11), 1294-1303, 2007
702007
Chemoenzymatic synthesis and in situ application of S-adenosyl-L-methionine analogs
M Thomsen, SB Vogensen, J Buchardt, MD Burkart, RP Clausen
Organic & biomolecular chemistry 11 (43), 7606-7610, 2013
602013
Analogues of the Natural Product Sinefungin as Inhibitors of EHMT1 and EHMT2
K Devkota, B Lohse, Q Liu, MW Wang, D Stærk, J Berthelsen, RP Clausen
ACS medicinal chemistry letters 5 (4), 293-297, 2014
592014
Selective GABA transporter inhibitors tiagabine and EF1502 exhibit mechanistic differences in their ability to modulate the ataxia and anticonvulsant action of the …
KK Madsen, B Ebert, RP Clausen, P Krogsgaard-Larsen, A Schousboe, ...
Journal of Pharmacology and Experimental Therapeutics 338 (1), 214-219, 2011
532011
Novel cyclic γ-hydroxybutyrate (GHB) analogs with high affinity and stereoselectivity of binding to GHB sites in rat brain
P Wellendorph, S Høg, JR Greenwood, A de Lichtenberg, B Nielsen, ...
Journal of Pharmacology and Experimental Therapeutics 315 (1), 346-351, 2005
522005
Diagnostic evaluation of a nanobody with picomolar affinity toward the protease RgpB from Porphyromonas gingivalis
PD Skottrup, P Leonard, JZ Kaczmarek, F Veillard, JJ Enghild, ...
Analytical biochemistry 415 (2), 158-167, 2011
502011
A novel selective γ-aminobutyric acid transport inhibitor demonstrates a functional role for GABA transporter subtype GAT2/BGT-1 in the CNS
RP Clausen, B Frølund, OM Larsson, A Schousboe, P Krogsgaard-Larsen, ...
Neurochemistry international 48 (6-7), 637-642, 2006
502006
Differential role of AMPA receptors in mouse tests of antidepressant and anxiolytic action
JT Andreasen, CM Fitzpatrick, M Larsen, L Skovgaard, SD Nielsen, ...
Brain research 1601, 117-126, 2015
492015
P2X7 receptor-mediated analgesia in cancer-induced bone pain
S Falk, SD Schwab, M Frøsig-Jørgensen, RP Clausen, AH Dickenson, ...
Neuroscience 291, 93-105, 2015
452015
Does increasing the ratio of AMPA-to-NMDA receptor mediated neurotransmission engender antidepressant action? Studies in the mouse forced swim and tail suspension tests
JT Andreasen, M Gynther, A Rygaard, T Bøgelund, SD Nielsen, ...
Neuroscience Letters 546, 6-10, 2013
452013
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