Compartmentalization of interphase chromosomes observed in simulation and experiment C Münkel, R Eils, S Dietzel, D Zink, C Mehring, G Wedemann, T Cremer, ... Journal of molecular biology 285 (3), 1053-1065, 1999 | 261 | 1999 |
Computer simulation of the 30-nanometer chromatin fiber G Wedemann, J Langowski Biophysical journal 82 (6), 2847-2859, 2002 | 191 | 2002 |
Nucleosome geometry and internucleosomal interactions control the chromatin fiber conformation N Kepper, D Foethke, R Stehr, G Wedemann, K Rippe Biophysical journal 95 (8), 3692-3705, 2008 | 130 | 2008 |
Dissecting DNA-histone interactions in the nucleosome by molecular dynamics simulations of DNA unwrapping R Ettig, N Kepper, R Stehr, G Wedemann, K Rippe Biophysical journal 101 (8), 1999-2008, 2011 | 108 | 2011 |
DNA–DNA interactions in tight supercoils are described by a small effective charge density C Maffeo, R Schöpflin, H Brutzer, R Stehr, A Aksimentiev, G Wedemann, ... Physical review letters 105 (15), 158101, 2010 | 108 | 2010 |
The effect of internucleosomal interaction on folding of the chromatin fiber R Stehr, N Kepper, K Rippe, G Wedemann Biophysical journal 95 (8), 3677-3691, 2008 | 85 | 2008 |
Perforin-dependent direct cytotoxicity in natural killer cells induces considerable knockdown of spontaneous lung metastases and computer modelling-proven tumor cell dormancy … T Brodbeck, N Nehmann, A Bethge, G Wedemann, U Schumacher Molecular Cancer 13, 244, 2014 | 63 | 2014 |
TNFα signalling primes chromatin for NF-κB binding and induces rapid and widespread nucleosome repositioning S Diermeier, P Kolovos, L Heizinger, U Schwartz, T Georgomanolis, ... Genome biology 15, 1-13, 2014 | 53 | 2014 |
Exploring the conformational space of chromatin fibers and their stability by numerical dynamic phase diagrams R Stehr, R Schöpflin, R Ettig, N Kepper, K Rippe, G Wedemann Biophysical journal 98 (6), 1028-1037, 2010 | 47 | 2010 |
Modeling nucleosome position distributions from experimental nucleosome positioning maps R Schöpflin, VB Teif, O Müller, C Weinberg, K Rippe, G Wedemann Bioinformatics 29 (19), 2380-2386, 2013 | 46 | 2013 |
Probing the elasticity of DNA on short length scales by modeling supercoiling under tension R Schöpflin, H Brutzer, O Müller, R Seidel, G Wedemann Biophysical journal 103 (2), 323-330, 2012 | 45 | 2012 |
Changing chromatin fiber conformation by nucleosome repositioning O Müller, N Kepper, R Schöpflin, R Ettig, K Rippe, G Wedemann Biophysical journal 107 (9), 2141-2150, 2014 | 44 | 2014 |
Force spectroscopy of chromatin fibers: extracting energetics and structural information from Monte Carlo simulations N Kepper, R Ettig, R Stehr, S Marnach, G Wedemann, K Rippe Biopolymers 95 (7), 435-447, 2011 | 38 | 2011 |
Are metastases from metastases clinical relevant? Computer modelling of cancer spread in a case of hepatocellular carcinoma A Bethge, U Schumacher, A Wree, G Wedemann PLoS One 7 (4), e35689, 2012 | 28 | 2012 |
Affinity, stoichiometry and cooperativity of heterochromatin protein 1 (HP1) binding to nucleosomal arrays VB Teif, N Kepper, K Yserentant, G Wedemann, K Rippe Journal of Physics: Condensed Matter 27 (6), 064110, 2015 | 27 | 2015 |
Parallel high-performance grid computing: capabilities and opportunities of a novel demanding service and business class allowing highest resource efficiency. N Kepper, R Ettig, F Dickmann, R Stehr, FG Grosveld, G Wedemann, ... HealthGrid, 264-271, 2010 | 26 | 2010 |
Simulation of metastatic progression using a computer model including chemotherapy and radiation therapy A Bethge, U Schumacher, G Wedemann Journal of biomedical informatics 57, 74-87, 2015 | 22 | 2015 |
Kinetics of structural changes in superhelical DNA G Wedemann, C Münkel, G Schöppe, J Langowski Physical Review E 58 (3), 3537, 1998 | 18 | 1998 |
Scrum as a method of teaching software architecture G Wedemann Proceedings of the 3rd European Conference of Software engineering Education …, 2018 | 16 | 2018 |
Radiotherapy and chemotherapy change vessel tree geometry and metastatic spread in a small cell lung cancer xenograft mouse tumor model T Frenzel, B Hoffmann, R Schmitz, A Bethge, U Schumacher, ... PLoS One 12 (11), e0187144, 2017 | 9 | 2017 |