| Proteomic approach to understanding antibiotic action JE Bandow, H Brötz, LIO Leichert, H Labischinski, M Hecker Antimicrobial agents and chemotherapy 47 (3), 948-955, 2003 | 484 | 2003 |
| Role of lipid‐bound peptidoglycan precursors in the formation of pores by nisin, epidermin and other lantibiotics H Brötz, M Josten, I Wiedemann, U Schneider, F Götz, G Bierbaum, ... Molecular microbiology 30 (2), 317-327, 1998 | 446 | 1998 |
| Human commensals producing a novel antibiotic impair pathogen colonization A Zipperer, MC Konnerth, C Laux, A Berscheid, D Janek, C Weidenmaier, ... Nature 535 (7613), 511-516, 2016 | 439 | 2016 |
| Dysregulation of bacterial proteolytic machinery by a new class of antibiotics H Brötz-Oesterhelt, D Beyer, HP Kroll, R Endermann, C Ladel, ... Nature medicine 11 (10), 1082-1087, 2005 | 430 | 2005 |
| The lantibiotic mersacidin inhibits peptidoglycan synthesis by targeting lipid II H Brötz, G Bierbaum, K Leopold, PE Reynolds, HG Sahl Antimicrobial agents and chemotherapy 42 (1), 154-160, 1998 | 420 | 1998 |
| Small cationic antimicrobial peptides delocalize peripheral membrane proteins M Wenzel, AI Chiriac, A Otto, D Zweytick, C May, C Schumacher, R Gust, ... Proceedings of the National Academy of Sciences 111 (14), E1409-E1418, 2014 | 221 | 2014 |
| The lantibiotic mersacidin inhibits peptidoglycan biosynthesis at the level of transglycosylation H Brötz, G Bierbaum, PE Reynolds, HG Sahl European Journal of Biochemistry 246 (1), 193-199, 1997 | 220 | 1997 |
| Structures of ClpP in complex with acyldepsipeptide antibiotics reveal its activation mechanism BG Lee, EY Park, KE Lee, H Jeon, KH Sung, H Paulsen, ... Nature structural & molecular biology 17 (4), 471, 2010 | 190 | 2010 |
| The antibiotic ADEP reprogrammes ClpP, switching it from a regulated to an uncontrolled protease J Kirstein, A Hoffmann, H Lilie, R Schmidt, H Rübsamen‐Waigmann, ... EMBO molecular medicine 1 (1), 37-49, 2009 | 181 | 2009 |
| Mode of action of the lantibiotic mersacidin: inhibition of peptidoglycan biosynthesis via a novel mechanism? H Brötz, G Bierbaum, A Markus, E Molitor, HG Sahl Antimicrobial agents and chemotherapy 39 (3), 714-719, 1995 | 169 | 1995 |
| Inducing Secondary Metabolite Production by the Endophytic Fungus Fusarium tricinctum through Coculture with Bacillus subtilis ARB Ola, D Thomy, D Lai, H Brötz-Oesterhelt, P Proksch Journal of natural products 76 (11), 2094-2099, 2013 | 164 | 2013 |
| Antibiotic acyldepsipeptides activate ClpP peptidase to degrade the cell division protein FtsZ P Sass, M Josten, K Famulla, G Schiffer, HG Sahl, L Hamoen, ... Proceedings of the National Academy of Sciences 108 (42), 17474-17479, 2011 | 154 | 2011 |
| New insights into the mechanism of action of lantibiotics—diverse biological effects by binding to the same molecular target H Brötz, HG Sahl Journal of Antimicrobial Chemotherapy 46 (1), 1-6, 2000 | 152 | 2000 |
| Specific and potent inhibition of NAD+-dependent DNA ligase by pyridochromanones H Brötz-Oesterhelt, I Knezevic, S Bartel, T Lampe, U Warnecke-Eberz, ... Journal of Biological Chemistry 278 (41), 39435-39442, 2003 | 126 | 2003 |
| Postgenomic strategies in antibacterial drug discovery H Brötz-Oesterhelt, P Sass Future microbiology 5 (10), 1553-1579, 2010 | 116 | 2010 |
| Identification of novel essential Escherichia coli genes conserved among pathogenic bacteria C Freiberg, B Wieland, F Spaltmann, K Ehlert, H Brotz, H Labischinski Journal of molecular microbiology and biotechnology 3 (3), 483-489, 2001 | 116 | 2001 |
| How many modes of action should an antibiotic have? H Brötz-Oesterhelt, NA Brunner Current opinion in pharmacology 8 (5), 564-573, 2008 | 106 | 2008 |
| Cloning, sequencing and production of the lantibiotic mersacidin G Bierbaum, H Brötz, KP Koller, HG Sahl FEMS microbiology letters 127 (1-2), 121-126, 1995 | 102 | 1995 |
| Medicinal chemistry optimization of acyldepsipeptides of the enopeptin class antibiotics B Hinzen, S Raddatz, H Paulsen, T Lampe, A Schumacher, D Häbich, ... ChemMedChem: Chemistry Enabling Drug Discovery 1 (7), 689-693, 2006 | 95 | 2006 |
| AAA+ chaperones and acyldepsipeptides activate the ClpP protease via conformational control M Gersch, K Famulla, M Dahmen, C Göbl, I Malik, K Richter, VS Korotkov, ... Nature communications 6 (1), 1-12, 2015 | 86 | 2015 |
Hans Georg SahlUniversität BonnBestätigte E-Mail-Adresse bei uni-bonn.de
