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Yevhen Akimov
Yevhen Akimov
Institute For Molecular Medicine Finland
Verified email at helsinki.fi
Title
Cited by
Cited by
Year
Antiviral properties of chemical inhibitors of cellular anti-apoptotic Bcl-2 proteins
D Bulanova, A Ianevski, A Bugai, Y Akimov, S Kuivanen, H Paavilainen, ...
Viruses 9 (10), 271, 2017
442017
Network pharmacology modeling identifies synergistic Aurora B and ZAK interaction in triple-negative breast cancer
J Tang, P Gautam, A Gupta, L He, S Timonen, Y Akimov, W Wang, ...
NPJ systems biology and applications 5 (1), 20, 2019
282019
Re-defining synthetic lethality by phenotypic profiling for precision oncology
Y Akimov, T Aittokallio
Cell chemical biology 28 (3), 246-256, 2021
192021
Improved detection of differentially represented DNA barcodes for high‐throughput clonal phenomics
Y Akimov, D Bulanova, S Timonen, K Wennerberg, T Aittokallio
Molecular Systems Biology 16 (3), e9195, 2020
192020
Orphan G protein-coupled receptor GPRC5A modulates integrin β1-mediated epithelial cell adhesion
DR Bulanova, YA Akimov, A Rokka, TD Laajala, T Aittokallio, P Kouvonen, ...
Cell adhesion & migration 11 (5-6), 434-446, 2017
192017
Chemical, physical and biological triggers of evolutionary conserved Bcl-xL-mediated apoptosis
A Ianevski, E Kulesskiy, K Krpina, G Lou, Y Aman, A Bugai, K Aasumets, ...
Cancers 12 (6), 1694, 2020
172020
Seed-effect modeling improves the consistency of genome-wide loss-of-function screens and identifies synthetic lethal vulnerabilities in cancer cells
A Jaiswal, G Peddinti, Y Akimov, K Wennerberg, S Kuznetsov, J Tang, ...
Genome medicine 9, 1-15, 2017
172017
Genetic and functional implications of an exonic TRIM55 variant in heart failure
J Heliste, H Chheda, I Paatero, TA Salminen, Y Akimov, J Paavola, ...
Journal of Molecular and Cellular Cardiology 138, 222-233, 2020
102020
Multi‐modal meta‐analysis of cancer cell line omics profiles identifies ECHDC1 as a novel breast tumor suppressor
A Jaiswal, P Gautam, EA Pietilä, S Timonen, N Nordström, Y Akimov, ...
Molecular systems biology 17 (3), e9526, 2021
92021
DNA barcode-guided lentiviral CRISPRa tool to trace and isolate individual clonal lineages in heterogeneous cancer cell populations
Y Akimov, D Bulanova, M Abyzova, K Wennerberg, T Aittokallio
Biorxiv, 622506, 2019
62019
Network pharmacology modeling identifies synergistic Aurora B and ZAK interaction in triple‑negative breast cancer. NPJ Syst Biol Appl. 2019; 5: 20
J Tang, P Gautam, A Gupta, L He, S Timonen, Y Akimov, W Wang, ...
5
CRISPRi screening reveals regulators of tau pathology shared between exosomal and vesicle-free tau
JC Polanco, Y Akimov, A Fernandes, A Briner, GR Hand, M van Roijen, ...
Life Science Alliance 6 (1), 2023
32023
A synthetic lethal dependency on casein kinase 2 in response to replication-perturbing drugs in RB1-deficient ovarian and breast cancer cells
D Bulanova, Y Akimov, W Senkowski, J Oikkonen, L Gall-Mas, S Timonen, ...
bioRxiv, 2022.11. 14.516369, 2022
22022
P1228: GENOME-WIDE CRISPR-CAS9 SCREENING IDENTIFIES THERAPEUTIC TARGETS FOR MATURE T-CELL MALIGNANCIES
S Timonen, VR Gasparini, E Piekkari, O Dufva, S Awad, Y Akimov, ...
HemaSphere 7 (S3), e0412416, 2023
2023
Genome-wide CRISPRi screening reveals regulators of Alzheimer’s tau pathology shared between exosomal and vesicle-free tau seeds
JC Polanco, Y Akimov, A Fernandes, GR Hand, A Briner, M van Roijen, ...
bioRxiv, 2022.04. 26.489622, 2022
2022
A method to identify physical, chemical and biological factors that trigger Bcl-xL-mediated apoptosis
A Ianevski, E Kulesskiy, K Krpina, G Lou, Y Aman, A Bugai, K Aasumets, ...
bioRxiv, 2020.01. 13.904714, 2020
2020
A novel exonic variant in TRIM55 gene predisposes to heart failure
J Heliste, H Chheda, Y Akimov, I Paatero, K Elenius, T Aittokallio
EUROPEAN HEART JOURNAL 40, 655-655, 2019
2019
1179 A novel exonic variant in TRIM55 gene predisposes to heart failure
J Heliste, H Chheda, Y Akimov, I Paatero, K Elenius, T Aittokallio
European Heart Journal 40 (Supplement_1), ehz748. 0021, 2019
2019
Identification of internal tandem duplication within the FLT3 gene from AML patient next-generation sequence data
Y Akimov, S Eldfors, D Malani, T Aittokallio, C Heckman
Cancer Research 78 (13_Supplement), 3277-3277, 2018
2018
Landscape of somatic mutations in drug-resistant acute myeloid leukemia
S Eldfors, M Kontro, Y Akimov, O Kallioniemi, K Porkka, C Heckman
Cancer Research 77 (13_Supplement), 424-424, 2017
2017
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