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Andrew Gerard Cairns
Andrew Gerard Cairns
Principal Scientist, Lifearc
Bestätigte E-Mail-Adresse bei lifearc.org
Titel
Zitiert von
Zitiert von
Jahr
Selective uncoupling of individual mitochondria within a cell using a mitochondria-targeted photoactivated protonophore
S Chalmers, ST Caldwell, C Quin, TA Prime, AM James, AG Cairns, ...
Journal of the American Chemical Society 134 (2), 758-761, 2012
1302012
Individuals with higher metabolic rates have lower levels of reactive oxygen species in vivo
K Salin, SK Auer, AM Rudolf, GJ Anderson, AG Cairns, W Mullen, ...
Biology letters 11 (9), 20150538, 2015
1172015
MitoNeoD: A Mitochondria-Targeted Superoxide Probe
MM Shchepinova, AG Cairns, TA Prime, A Logan, AM James, AR Hall, ...
Cell chemical biology 24 (10), 1285-1298. e12, 2017
752017
Chemical disarming of isoniazid resistance in Mycobacterium tuberculosis
K Flentie, GA Harrison, H Tükenmez, J Livny, JAD Good, S Sarkar, ...
Proceedings of the National Academy of Sciences 116 (21), 10510-10517, 2019
552019
Translation of Diverse Aramid- and 1,3-Dicarbonyl-peptides by Wild Type Ribosomes in Vitro
O Ad, KS Hoffman, AG Cairns, AL Featherston, SJ Miller, D Söll, ...
ACS central science 5 (7), 1289-1294, 2019
472019
The influence of precursor source and thermal parameters upon the formation of beta-phase molybdenum nitride
AG Cairns, JG Gallagher, JSJ Hargreaves, D Mckay, E Morrison, JL Rico, ...
Journal of Alloys and Compounds 479 (1-2), 851-854, 2009
372009
Structure-Based Design of Inhibitors Targeting PrfA, the Master Virulence Regulator of Listeria monocytogenes
M Kulen, M Lindgren, S Hansen, AG Cairns, C Grundstrom, A Begum, ...
Journal of medicinal chemistry 61 (9), 4165-4175, 2018
272018
The effect of low levels of dopants upon the formation and properties of beta-phase molybdenum nitride
AG Cairns, JG Gallagher, JSJ Hargreaves, D Mckay, JL Rico, K Wilson
Journal of Solid State Chemistry 183 (3), 613-619, 2010
272010
Targeting mitochondria with small molecules: the preparation of MitoB and MitoP as exomarkers of mitochondrial hydrogen peroxide
AG Cairns, SJ McQuaker, MP Murphy, RC Hartley
Mitochondrial Medicine: Volume II, Manipulating Mitochondrial Function, 25-50, 2015
262015
Pyridine-Fused 2-Pyridones via Povarov and A3 Reactions: Rapid Generation of Highly Functionalized Tricyclic Heterocycles Capable of Amyloid Fibril Binding
P Singh, DE Adolfsson, J Ådén, AG Cairns, C Bartens, K Brännström, ...
The Journal of organic chemistry 84 (7), 3887-3903, 2019
232019
Viral mimetic priming enhances α-synuclein-induced degeneration: Implications for Parkinson’s disease
LK Olsen, AG Cairns, J Ådén, N Moriarty, S Cabre, VR Alamilla, ...
Brain, behavior, and immunity 80, 525-535, 2019
202019
Using the MitoB method to assess levels of reactive oxygen species in ecological studies of oxidative stress
K Salin, SK Auer, EM Villasevil, GJ Anderson, AG Cairns, W Mullen, ...
Scientific Reports 7 (1), 41228, 2017
202017
Expanding the palette of phenanthridinium cations
AG Cairns, HM Senn, MP Murphy, RC Hartley
Chemistry-A European Journal 20 (13), 3742-3751, 2014
182014
Synthesis of Densely Functionalized N-Alkenyl 2-Pyridones via Benzyne-Induced Ring Opening of Thiazolino-Fused 2-Pyridones
P Singh, AG Cairns, DE Adolfsson, J Ådén, UH Sauer, F Almqvist
Organic letters 21 (17), 6946-6950, 2019
172019
Regio- and Stereoselective Alkylation of Pyridine-N-oxides: Synthesis of Substituted Piperidines and Pyridines
DK Barange, MT Johnson, AG Cairns, R Olsson, F Almqvist
Organic letters 18 (24), 6228-6231, 2016
102016
Methyl sulfonamide substituents improve the pharmacokinetic properties of bicyclic 2-pyridone based Chlamydia trachomatis inhibitors
M Kulén, C Núñez-Otero, AG Cairns, J Silver, AEG Lindgren, E Wede, ...
MedChemComm 10 (11), 1966-1987, 2019
62019
Increased Brain Exposure of an Alpha-Synuclein Fibrillization Modulator by Utilization of an Activated Ester Prodrug Strategy
AG Cairns, A Vazquez-Romero, M Mahdi Moein, J Ådén, CS Elmore, ...
ACS Chemical Neuroscience 9 (11), 2542-2547, 2018
62018
3-Fluorobenzoic acid–4-acetylpyridine (1/1) at 100 K
GA Craig, LH Thomas, MS Adam, A Ballantyne, A Cairns, SC Cairns, ...
Acta Crystallographica Section E: Structure Reports Online 65 (2), o380-o380, 2009
62009
The Small Molecule Alpha-Synuclein Aggregator, FN075, Enhances Alpha-Synuclein Pathology in Subclinical AAV Rat Models
R Kelly, AG Cairns, J Ådén, F Almqvist, AP Bemelmans, E Brouillet, ...
Biomolecules 11 (11), 1685, 2021
52021
Synthesis of an azido-tagged low affinity ratiometric calcium sensor
ST Caldwell, AG Cairns, M Olson, S Chalmers, M Sandison, W Mullen, ...
Tetrahedron 71 (51), 9571-9578, 2015
52015
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