| Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system B Zetsche, JS Gootenberg, OO Abudayyeh, IM Slaymaker, KS Makarova, ... Cell 163 (3), 759-771, 2015 | 3793 | 2015 |
| Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex S Konermann, MD Brigham, AE Trevino, J Joung, OO Abudayyeh, ... Nature 517 (7536), 583-588, 2015 | 2426 | 2015 |
| Nucleic acid detection with CRISPR-Cas13a/C2c2 JS Gootenberg, OO Abudayyeh, JW Lee, P Essletzbichler, AJ Dy, J Joung, ... Science 356 (6336), 438-442, 2017 | 2023 | 2017 |
| C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector OO Abudayyeh, JS Gootenberg, S Konermann, J Joung, IM Slaymaker, ... Science 353 (6299), aaf5573, 2016 | 1654 | 2016 |
| Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6 JS Gootenberg, OO Abudayyeh, MJ Kellner, J Joung, JJ Collins, F Zhang Science 360 (6387), 439-444, 2018 | 1418 | 2018 |
| RNA targeting with CRISPR–Cas13 OO Abudayyeh, JS Gootenberg, P Essletzbichler, S Han, J Joung, ... Nature 550 (7675), 280-284, 2017 | 1354 | 2017 |
| RNA editing with CRISPR-Cas13 DBT Cox, JS Gootenberg, OO Abudayyeh, B Franklin, MJ Kellner, J Joung, ... Science 358 (6366), 1019-1027, 2017 | 1290 | 2017 |
| Discovery and functional characterization of diverse class 2 CRISPR-Cas systems S Shmakov, OO Abudayyeh, KS Makarova, YI Wolf, JS Gootenberg, ... Molecular cell 60 (3), 385-397, 2015 | 1089 | 2015 |
| Field-deployable viral diagnostics using CRISPR-Cas13 C Myhrvold, CA Freije, JS Gootenberg, OO Abudayyeh, HC Metsky, ... Science 360 (6387), 444-448, 2018 | 863 | 2018 |
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| Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening J Joung, S Konermann, JS Gootenberg, OO Abudayyeh, RJ Platt, ... Nature protocols 12 (4), 828-863, 2017 | 789 | 2017 |
| Multiplex gene editing by CRISPR–Cpf1 using a single crRNA array B Zetsche, M Heidenreich, P Mohanraju, I Fedorova, J Kneppers, ... Nature biotechnology 35 (1), 31-34, 2017 | 753 | 2017 |
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| SHERLOCK: nucleic acid detection with CRISPR nucleases MJ Kellner, JG Koob, JS Gootenberg, OO Abudayyeh, F Zhang Nature protocols 14 (10), 2986-3012, 2019 | 670 | 2019 |
| A Melanoma Cell State Distinction Influences Sensitivity to MAPK Pathway InhibitorsMelanoma Cell State Affects Intrinsic MAPK Inhibitor Resistance DJ Konieczkowski, CM Johannessen, O Abudayyeh, JW Kim, ZA Cooper, ... Cancer discovery 4 (7), 816-827, 2014 | 490 | 2014 |
| Cas13b is a type VI-B CRISPR-associated RNA-guided RNase differentially regulated by accessory proteins Csx27 and Csx28 AA Smargon, DBT Cox, NK Pyzocha, K Zheng, IM Slaymaker, ... Molecular cell 65 (4), 618-630. e7, 2017 | 461 | 2017 |
| Detection of SARS-CoV-2 with SHERLOCK one-pot testing J Joung, A Ladha, M Saito, NG Kim, AE Woolley, M Segel, RPJ Barretto, ... New England Journal of Medicine 383 (15), 1492-1494, 2020 | 415 | 2020 |
| CRISPR enzymes and systems F Zhang, B Zetsche, I Slaymaker, J Gootenberg, OO Abudayyeh US Patent 9,790,490, 2017 | 374 | 2017 |
| Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood J Joung, JM Engreitz, S Konermann, OO Abudayyeh, VK Verdine, F Aguet, ... Nature 548 (7667), 343-346, 2017 | 341 | 2017 |
| Clinical validation of a Cas13-based assay for the detection of SARS-CoV-2 RNA M Patchsung, K Jantarug, A Pattama, K Aphicho, S Suraritdechachai, ... Nature biomedical engineering 4 (12), 1140-1149, 2020 | 337 | 2020 |
Jonathan S. GootenbergMcGovern Fellow, MITVerified email at mit.edu
