GLUT1 mutations are a cause of paroxysmal exertion-induced dyskinesias and induce hemolytic anemia by a cation leak YG Weber, A Storch, TV Wuttke, K Brockmann, J Kempfle, S Maljevic, ... The Journal of clinical investigation 118 (6), 2157-2168, 2008 | 389 | 2008 |
Paroxysmal exercise-induced dyskinesia and epilepsy is due to mutations in SLC2A1, encoding the glucose transporter GLUT1 A Suls, P Dedeken, K Goffin, H Van Esch, P Dupont, D Cassiman, ... Brain 131 (7), 1831-1844, 2008 | 380 | 2008 |
The new anticonvulsant retigabine favors voltage-dependent opening of the Kv7. 2 (KCNQ2) channel by binding to its activation gate TV Wuttke, G Seebohm, S Bail, S Maljevic, H Lerche Molecular pharmacology 67 (4), 1009-1017, 2005 | 310 | 2005 |
Early‐onset absence epilepsy caused by mutations in the glucose transporter GLUT1 A Suls, SA Mullen, YG Weber, K Verhaert, B Ceulemans, R Guerrini, ... Annals of Neurology: Official Journal of the American Neurological …, 2009 | 303 | 2009 |
A community-based transcriptomics classification and nomenclature of neocortical cell types R Yuste, M Hawrylycz, N Aalling, A Aguilar-Valles, D Arendt, ... Nature neuroscience 23 (12), 1456-1468, 2020 | 199 | 2020 |
Nervous system KV7 disorders: breakdown of a subthreshold brake S Maljevic, TV Wuttke, H Lerche The Journal of physiology 586 (7), 1791-1801, 2008 | 193 | 2008 |
KV7 channelopathies S Maljevic, TV Wuttke, G Seebohm, H Lerche Pflügers Archiv-European Journal of Physiology 460, 277-288, 2010 | 143 | 2010 |
Peripheral nerve hyperexcitability due to dominant-negative KCNQ2 mutations TV Wuttke, K Jurkat-Rott, W Paulus, M Garncarek, F Lehmann-Horn, ... Neurology 69 (22), 2045-2053, 2007 | 137 | 2007 |
Paroxysmal choreoathetosis/spasticity (DYT9) is caused by a GLUT1 defect YG Weber, C Kamm, A Suls, J Kempfle, K Kotschet, R Schüle, TV Wuttke, ... Neurology 77 (10), 959-964, 2011 | 119 | 2011 |
Mutations in GABRB3 From febrile seizures to epileptic encephalopathies RS Møller, TV Wuttke, I Helbig, C Marini, KM Johannesen, EH Brilstra, ... Neurology 88 (5), 483-492, 2017 | 113 | 2017 |
Predictors of preoperative and early postoperative seizures in patients with intra‐axial primary and metastatic brain tumors: a retrospective observational single center study M Skardelly, E Brendle, S Noell, F Behling, TV Wuttke, J Schittenhelm, ... Annals of Neurology 78 (6), 917-928, 2015 | 79 | 2015 |
Long-term adult human brain slice cultures as a model system to study human CNS circuitry and disease N Schwarz, B Uysal, M Welzer, JC Bahr, N Layer, H Löffler, K Stanaitis, ... Elife 8, e48417, 2019 | 67 | 2019 |
Human Cerebrospinal fluid promotes long-term neuronal viability and network function in human neocortical organotypic brain slice cultures N Schwarz, UBS Hedrich, H Schwarz, H PA, N Dammeier, E Auffenberg, ... Scientific reports 7 (1), 12249, 2017 | 67 | 2017 |
Differential roles of S6 domain hinges in the gating of KCNQ potassium channels G Seebohm, N Strutz-Seebohm, ON Ureche, R Baltaev, A Lampert, ... Biophysical journal 90 (6), 2235-2244, 2006 | 60 | 2006 |
Retigabine/Ezogabine, a KCNQ/KV7 channel opener: pharmacological and clinical data G Orhan, TV Wuttke, AT Nies, M Schwab, H Lerche Expert opinion on pharmacotherapy 13 (12), 1807-1816, 2012 | 54 | 2012 |
Risk factors of preoperative and early postoperative seizures in patients with meningioma: a retrospective single-center cohort study M Skardelly, C Rother, S Noell, F Behling, TV Wuttke, J Schittenhelm, ... World Neurosurgery 97, 538-546, 2017 | 42 | 2017 |
Neutralization of a negative charge in the S1–S2 region of the KV7. 2 (KCNQ2) channel affects voltage‐dependent activation in neonatal epilepsy TV Wuttke, J Penzien, M Fauler, G Seebohm, F Lehmann‐Horn, H Lerche, ... The Journal of physiology 586 (2), 545-555, 2008 | 42 | 2008 |
Novel anticonvulsant drugs targeting voltage-dependent ion channels TV Wuttke, H Lerche Expert Opinion on Investigational Drugs 15 (10), 1167-1177, 2006 | 41 | 2006 |
Hyperexcitable interneurons trigger cortical spreading depression in an Scn1a migraine model E Auffenberg, UBS Hedrich, R Barbieri, D Miely, B Groschup, TV Wuttke, ... The Journal of clinical investigation 131 (21), 2021 | 38 | 2021 |
Frame-based and robot-assisted insular stereo-electroencephalography via an anterior or posterior oblique approach K Machetanz, F Grimm, TV Wuttke, J Kegele, H Lerche, M Tatagiba, ... Journal of Neurosurgery 135 (5), 1477-1486, 2021 | 23 | 2021 |