| Identification of neutral tumor evolution across cancer types MJ Williams, B Werner, CP Barnes, TA Graham, A Sottoriva Nature genetics 48 (3), 238, 2016 | 293 | 2016 |
| Quantification of subclonal selection in cancer from bulk sequencing data MJ Williams, B Werner, T Heide, C Curtis, CP Barnes, A Sottoriva, ... Nature genetics 50 (6), 895, 2018 | 62 | 2018 |
| Dynamics of mutant cells in hierarchical organized tissues B Werner, D Dingli, T Lenaerts, JM Pacheco, A Traulsen PLoS computational biology 7 (12), e1002290, 2011 | 55 | 2011 |
| Longitudinal liquid biopsy and mathematical modeling of clonal evolution forecast time to treatment failure in the PROSPECT-C phase II colorectal cancer clinical trial KH Khan, D Cunningham, B Werner, G Vlachogiannis, I Spiteri, T Heide, ... Cancer discovery 8 (10), 1270-1285, 2018 | 49 | 2018 |
| A deterministic model for the occurrence and dynamics of multiple mutations in hierarchically organized tissues B Werner, D Dingli, A Traulsen Journal of The Royal Society Interface 10 (85), 20130349, 2013 | 39 | 2013 |
| The cancer stem cell fraction in hierarchically organized tumors can be estimated using mathematical modeling and patient-specific treatment trajectories B Werner, JG Scott, A Sottoriva, ARA Anderson, A Traulsen, PM Altrock Cancer research 76 (7), 1705-1713, 2016 | 38 | 2016 |
| Reconstructing the in vivo dynamics of hematopoietic stem cells from telomere length distributions B Werner, F Beier, S Hummel, S Balabanov, L Lassay, T Orlikowsky, ... eLife, e08687v2, 2015 | 37 | 2015 |
| Dynamics of leukemia stem-like cell extinction in acute promyelocytic leukemia B Werner, RE Gallagher, EM Paietta, MR Litzow, MS Tallman, PH Wiernik, ... Cancer research 74 (19), 5386-5396, 2014 | 18 | 2014 |
| Should tissue structure suppress or amplify selection to minimize cancer risk? L Hindersin, B Werner, D Dingli, A Traulsen Biology direct 11 (1), 41, 2016 | 15 | 2016 |
| Self-tolerance in a minimal model of the idiotypic network R Schulz, BD Werner, U Behn Frontiers in immunology 5, 86, 2014 | 15 | 2014 |
| Dynamical trade-offs arise from antagonistic coevolution and decrease intraspecific diversity W Huang, A Traulsen, B Werner, T Hiltunen, L Becks Nature communications 8 (1), 2059, 2017 | 13 | 2017 |
| Dynamics of resistance development to imatinib under increasing selection pressure: a combination of mathematical models and in vitro data B Werner, D Lutz, TH Brümmendorf, A Traulsen, S Balabanov PLoS One 6 (12), e28955, 2011 | 13 | 2011 |
| Carbon dating cancer: defining the chronology of metastatic progression in colorectal cancer H Lote, I Spiteri, L Ermini, A Vatsiou, A Roy, A McDonald, N Maka, ... Annals of Oncology 28 (6), 1243-1249, 2017 | 12 | 2017 |
| Detecting truly clonal alterations from multi-region profiling of tumours B Werner, A Traulsen, A Sottoriva, D Dingli Scientific reports 7, 44991, 2017 | 12 | 2017 |
| The impact of random frequency-dependent mutations on the average population fitness W Huang, B Werner, A Traulsen BMC Evolutionary Biology 12 (1), 160, 2012 | 11 | 2012 |
| Reply to ‘Neutral tumor evolution?’ T Heide, L Zapata, MJ Williams, B Werner, G Caravagna, CP Barnes, ... Nature genetics 50 (12), 1633, 2018 | 7 | 2018 |
| Evolutionary dynamics of residual disease in human glioblastoma I Spiteri, G Caravagna, GD Cresswell, A Vatsiou, D Nichol, A Acar, ... Annals of Oncology 30 (3), 456-463, 2018 | 7 | 2018 |
| Variation of mutational burden in healthy human tissues suggests non-random strand segregation and allows measuring somatic mutation rates B Werner, A Sottoriva PLoS computational biology 14 (6), e1006233, 2018 | 7 | 2018 |
| Ontogenic growth as the root of fundamental differences between childhood and adult cancer B Werner, A Traulsen, D Dingli Stem Cells 34 (3), 543-550, 2016 | 6 | 2016 |
| Replicative cellular age distributions in compartmentalized tissues MA Böttcher, D Dingli, B Werner, A Traulsen Journal of The Royal Society Interface 15 (145), 20180272, 2018 | 5 | 2018 |
Andrea SottorivaThe Institute of Cancer ResearchVerified email at icr.ac.uk
