| Synthesis, biological evaluation, and computational studies of Tri-and tetracyclic nitrogen-bridgehead compounds as potent dual-acting AChE inhibitors and h H3 receptor antagonists FH Darras, S Pockes, G Huang, S Wehle, A Strasser, HJ Wittmann, ... ACS chemical neuroscience 5 (3), 225-242, 2014 | 74 | 2014 |
| The dual-acting AChE inhibitor and H3 receptor antagonist UW-MD-72 reverses amnesia induced by scopolamine or dizocilpine in passive avoidance paradigm in rats B Sadek, N Khan, FH Darras, S Pockes, M Decker Physiology & behavior 165, 383-391, 2016 | 36 | 2016 |
| Highly Potent, Stable, and Selective Dimeric Hetarylpropylguanidine-Type Histamine H2 Receptor Agonists† S Pockes, D Wifling, M Keller, A Buschauer, S Elz ACS omega 3 (3), 2865-2882, 2018 | 20 | 2018 |
| A dynamic, split-luciferase-based mini-G protein sensor to functionally characterize ligands at all four histamine receptor subtypes C Höring, U Seibel, K Tropmann, L Grätz, D Mönnich, S Pitzl, G Bernhardt, ... International Journal of Molecular Sciences 21 (22), 8440, 2020 | 18 | 2020 |
| Development of a Conformational Histamine H3 Receptor Biosensor for the Synchronous Screening of Agonists and Inverse Agonists H Schihada, X Ma, U Zabel, HF Vischer, G Schulte, R Leurs, S Pockes, ... ACS sensors 5 (6), 1734-1742, 2020 | 16 | 2020 |
| A Versatile Sub-Nanomolar Fluorescent Ligand Enables NanoBRET Binding Studies and Single-Molecule Microscopy at the Histamine H3 Receptor N Rosier, L Grätz, H Schihada, J Möller, A Isbilir, LJ Humphrys, M Nagl, ... Journal of Medicinal Chemistry 64 (15), 11695-11708, 2021 | 13 | 2021 |
| A Split Luciferase Complementation Assay for the Quantification of β-Arrestin2 Recruitment to Dopamine D2-Like Receptors L Forster, L Grätz, D Mönnich, G Bernhardt, S Pockes International Journal of Molecular Sciences 21 (17), 6103, 2020 | 13 | 2020 |
| NanoBRET binding assay for histamine H2 receptor ligands using live recombinant HEK293T cells L Grätz, K Tropmann, M Bresinsky, C Müller, G Bernhardt, S Pockes Scientific Reports 10 (1), 1-10, 2020 | 13 | 2020 |
| Structural and Molecular Insight into Piperazine and Piperidine Derivatives as Histamine H3 and Sigma-1 Receptor Antagonists with Promising Antinociceptive … K Szczepańska, S Podlewska, M Dichiara, D Gentile, V Patamia, N Rosier, ... ACS Chemical Neuroscience 13 (1), 1-15, 2021 | 10 | 2021 |
| Cardiac effects of novel histamine H2 receptor agonists U Gergs, ML Büxel, M Bresinsky, U Kirchhefer, C Fehse, C Höring, ... Journal of Pharmacology and Experimental Therapeutics 379 (3), 223-234, 2021 | 10 | 2021 |
| Structural modifications in the distal, regulatory region of histamine H3 receptor antagonists leading to the identification of a potent anti-obesity agent K Szczepańska, S Pockes, S Podlewska, C Höring, K Mika, G Latacz, ... European Journal of Medicinal Chemistry 213, 113041, 2021 | 10 | 2021 |
| Light‐Switchable Antagonists for the Histamine H1 Receptor at the Isolated Guinea Pig Ileum K Rustler, S Pockes, B König ChemMedChem 14 (6), 636-644, 2019 | 8 | 2019 |
| Structure-based design and biological evaluation of novel caspase-2 inhibitors based on the peptide AcVDVAD-CHO and the caspase-2-mediated tau cleavage sequence YKPVD314 M Bresinsky, JM Strasser, B Vallaster, P Liu, WM McCue, J Fuller, ... ACS Pharmacology & Translational Science 5 (1), 20-40, 2022 | 6 | 2022 |
| Pharmacological characterization of a new series of carbamoylguanidines reveals potent agonism at the H2R and D3R S Biselli, M Bresinsky, K Tropmann, L Forster, C Honisch, A Buschauer, ... European Journal of Medicinal Chemistry 214, 113190, 2021 | 6 | 2021 |
| Discovery of a G Protein-Biased Radioligand for the Histamine H2 Receptor with Reversible Binding Properties K Tropmann, C Höring, N Plank, S Pockes Journal of Medicinal Chemistry 63 (21), 13090-13102, 2020 | 5 | 2020 |
| Abolishing Dopamine D2long/D3 Receptor Affinity of Subtype-Selective Carbamoylguanidine-Type Histamine H2 Receptor Agonists K Tropmann, M Bresinsky, L Forster, D Mönnich, A Buschauer, ... Journal of Medicinal Chemistry 64 (12), 8684-8709, 2021 | 4 | 2021 |
| Structure‐Activity Relationship of Hetarylpropylguanidines Aiming at the Development of Selective Histamine Receptor Ligands† S Pockes, D Wifling, A Buschauer, S Elz ChemistryOpen 8 (3), 285-297, 2019 | 3 | 2019 |
| Caspase-2 inhibitor blocks Tau truncation and restores excitatory neurotransmission in neurons modeling FTDP-17 tauopathy G Singh, P Liu, KR Yao, JM Strasser, C Hlynialuk, K Leinonen-Wright, ... ACS chemical neuroscience 13 (10), 1549-1557, 2022 | 2 | 2022 |
| Characterization of caspase‐2 inhibitors based on specific sites of caspase‐2‐mediated proteolysis M Bresinsky, JM Strasser, A Hubmann, B Vallaster, WM McCue, J Fuller, ... Archiv der Pharmazie 355 (9), 2200095, 2022 | 1 | 2022 |
| Investigating the ligand agonism and antagonism at the D2long receptor by dynamic mass redistribution L Forster, S Pockes Scientific Reports 12 (1), 9637, 2022 | 1 | 2022 |
