Lars Paeger
Lars Paeger
Novo Nordisk Postdoctoral Fellow for Metabolism Research, Karolinska Institutet, Stockholm, Sweden
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Neonatal insulin action impairs hypothalamic neurocircuit formation in response to maternal high-fat feeding
MC Vogt, L Paeger, S Hess, SM Steculorum, M Awazawa, B Hampel, ...
Cell 156 (3), 495-509, 2014
AgRP neurons control systemic insulin sensitivity via myostatin expression in brown adipose tissue
SM Steculorum, J Ruud, I Karakasilioti, H Backes, LE Ruud, K Timper, ...
Cell 165 (1), 125-138, 2016
High-fat feeding promotes obesity via insulin receptor/PI3K-dependent inhibition of SF-1 VMH neurons
T Klöckener, S Hess, BF Belgardt, L Paeger, LAW Verhagen, A Husch, ...
Nature neuroscience 14 (7), 911-918, 2011
Distinct roles for JNK and IKK activation in agouti-related peptide neurons in the development of obesity and insulin resistance
E Tsaousidou, L Paeger, BF Belgardt, M Pal, CM Wunderlich, H Brönneke, ...
Cell reports 9 (4), 1495-1506, 2014
AFG3L2 supports mitochondrial protein synthesis and Purkinje cell survival
ER Almajan, R Richter, L Paeger, P Martinelli, E Barth, T Decker, ...
The Journal of clinical investigation 122 (11), 4048-4058, 2012
Functionally distinct POMC-expressing neuron subpopulations in hypothalamus revealed by intersectional targeting
N Biglari, I Gaziano, J Schumacher, J Radermacher, L Paeger, P Klemm, ...
Nature neuroscience 24 (7), 913-929, 2021
PNOCARC neurons promote hyperphagia and obesity upon high-fat-diet feeding
A Jais, L Paeger, T Sotelo-Hitschfeld, S Bremser, M Prinzensteiner, ...
Neuron 106 (6), 1009-1025. e10, 2020
Hypothalamic UDP increases in obesity and promotes feeding via P2Y6-dependent activation of AgRP neurons
SM Steculorum, L Paeger, S Bremser, N Evers, Y Hinze, M Idzko, ...
Cell 162 (6), 1404-1417, 2015
Antagonistic modulation of NPY/AgRP and POMC neurons in the arcuate nucleus by noradrenalin
L Paeger, I Karakasilioti, J Altmüller, P Frommolt, J Brüning, ...
Elife 6, e25770, 2017
Energy imbalance alters Ca2+ handling and excitability of POMC neurons
L Paeger, A Pippow, S Hess, M Paehler, AC Klein, A Husch, C Pouzat, ...
Elife 6, e25641, 2017
AgRP innervation onto POMC neurons increases with age and is accelerated with chronic high-fat feeding in male mice
AJ Newton, S Hess, L Paeger, MC Vogt, J Fleming Lascano, EA Nillni, ...
Endocrinology 154 (1), 172-183, 2013
Calcium current diversity in physiologically different local interneuron types of the antennal lobe
A Husch, M Paehler, D Fusca, L Paeger, P Kloppenburg
Journal of Neuroscience 29 (3), 716-726, 2009
Distinct Electrophysiological Properties in Subtypes of Nonspiking Olfactory Local Interneurons Correlate With Their Cell Type–Specific Ca2+ Current Profiles
A Husch, M Paehler, D Fusca, L Paeger, P Kloppenburg
Journal of neurophysiology 102 (5), 2834-2845, 2009
Inhibition of P2Y6 signaling in AgRP neurons reduces food intake and improves systemic insulin sensitivity in obesity
SM Steculorum, K Timper, LE Ruud, N Evers, L Paeger, S Bremser, ...
Cell Reports 18 (7), 1587-1597, 2017
Mild impairment of mitochondrial OXPHOS promotes fatty acid utilization in POMC neurons and improves glucose homeostasis in obesity
K Timper, L Paeger, C Sánchez-Lasheras, L Varela, A Jais, H Nolte, ...
Cell reports 25 (2), 383-397. e10, 2018
KATP-Channel-dependent regulation of catecholaminergic neurons controls BAT sympathetic nerve activity and energy homeostasis
S Tovar, L Paeger, S Hess, DA Morgan, AC Hausen, HS Brönneke, ...
Cell metabolism 18 (3), 445-455, 2013
Neuronal actin dynamics, spine density and neuronal dendritic complexity are regulated by CAP2
A Kumar, L Paeger, K Kosmas, P Kloppenburg, AA Noegel, VS Peche
Frontiers in cellular neuroscience 10, 180, 2016
[18F]F-DED PET imaging of reactive astrogliosis in neurodegenerative diseases: preclinical proof of concept and first-in-human data
A Ballweg, C Klaus, L Vogler, S Katzdobler, K Wind, A Zatcepin, SI Ziegler, ...
Journal of Neuroinflammation 20 (1), 68, 2023
Analysis of neuronal Ca2+ handling properties by combining perforated patch clamp recordings and the added buffer approach
S Hess, C Pouzat, L Paeger, A Pippow, P Kloppenburg
Cell Calcium 97, 102411, 2021
Cortical circuit dysfunction in a mouse model of alpha-synucleinopathy in vivo
S Blumenstock, F Sun, C Klaus, P Marinković, C Sgobio, L Paeger, ...
Brain Communications 3 (4), fcab273, 2021
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