Frank J Bruggeman

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Hans WesterhoffUniversity of Amsterdam, VU University Amsterdam, University of ManchesterVerified email at manchester.ac.uk
Bas TeusinkProfessor of Systems Biology, VU University AmsterdamVerified email at vu.nl
Fred C. BoogerdMolecular Cell Biology, VU University Amsterdam, Assistant ProfessorVerified email at vu.nl
Robert PlanqueAssociate Prof, Dept of Mathematics, Vrije Universiteit AmsterdamVerified email at vu.nl
Brett G. OlivierVU AmsterdamVerified email at vu.nl
Snoep JLStellenbosch University; Manchester University; Vrije Universiteit AmsterdamVerified email at sun.ac.za
Boris KholodenkoProfessor of Systems Biology, University College DublinVerified email at ucd.ie
Jorrit HornbergAstraZenecaVerified email at astrazeneca.com
Barbara BakkerProfessor of Medical Systems Biololy, University of Groningen, University Medical Centre GroningenVerified email at umcg.nl
Douwe MolenaarVU University AmsterdamVerified email at vu.nl
Johan van HeerdenPhD student, Vrije Universiteit of AmsterdamVerified email at vu.nl
Alexey KolodkinLuxembourg Centre for Systems Biomedicine (Luxembourg)Verified email at uni.lu
Meike T WortelAssistant Professor, SILS, University of AmsterdamVerified email at uva.nl
Jan B. HoekProfessor, Thomas Jefferson UniversityVerified email at jefferson.edu
Timo MaarleveldCentrum Wiskunde InformaticaVerified email at cwi.nl
Daan H. de GrootPostdoc Computational Systems Biology, Biozentrum, Universitaet BaselVerified email at unibas.ch
Jan-Hendrik HofmeyrStellenbosch UniversityVerified email at sun.ac.za
Evert BosdrieszAssistant professor bioinformatics, Vrije Universiteit AmsterdamVerified email at vu.nl
Eduardo SontagNortheastern University ECE and BioEVerified email at northeastern.edu
Anatoly KiyatkinYale UniversityVerified email at yale.edu

Frank J Bruggeman

Professor, VU University

Verified email at vu.nl - Homepage

Systems biology computational biology biophysics


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The nature of systems biology FJ Bruggeman, HV Westerhoff TRENDS in Microbiology 15 (1), 45-50, 2007	606	2007
Cancer: a systems biology disease JJ Hornberg, FJ Bruggeman, HV Westerhoff, J Lankelma Biosystems 83 (2-3), 81-90, 2006	457	2006
Untangling the wires: a strategy to trace functional interactions in signaling and gene networks BN Kholodenko, A Kiyatkin, FJ Bruggeman, E Sontag, HV Westerhoff, ... Proceedings of the National Academy of Sciences 99 (20), 12841-12846, 2002	456	2002
Lost in transition: start-up of glycolysis yields subpopulations of nongrowing cells JH van Heerden, MT Wortel, FJ Bruggeman, JJ Heijnen, YJM Bollen, ... Science 343 (6174), 2014	252	2014
Systems biology: philosophical foundations F Boogerd, FJ Bruggeman, JHS Hofmeyr, HV Westerhoff Elsevier, 2007	229	2007
Control of MAPK signalling: from complexity to what really matters JJ Hornberg, B Binder, FJ Bruggeman, B Schoeberl, R Heinrich, ... Oncogene 24 (36), 5533-5542, 2005	221	2005
Emergence and its place in nature: A case study of biochemical networks FC Boogerd, FJ Bruggeman, RC Richardson, A Stephan, HV Westerhoff Synthese 145 (1), 131-164, 2005	217	2005
Principles behind the multifarious control of signal transduction: ERK phosphorylation and kinase/phosphatase control JJ Hornberg, FJ Bruggeman, B Binder, CR Geest, AJMB De Vaate, ... The FEBS journal 272 (1), 244-258, 2005	217	2005
Towards building the silicon cell: a modular approach JL Snoep, F Bruggeman, BG Olivier, HV Westerhoff Biosystems 83 (2-3), 207-216, 2006	162	2006
Effects of sequestration on signal transduction cascades N Blüthgen, FJ Bruggeman, S Legewie, H Herzel, HV Westerhoff, ... The FEBS journal 273 (5), 895-906, 2006	159	2006
Modular response analysis of cellular regulatory networks FJ Bruggeman, HV Westerhoff, JB Hoek, BN Kholodenko Journal of theoretical biology 218 (4), 507-520, 2002	153	2002
Community flux balance analysis for microbial consortia at balanced growth RA Khandelwal, BG Olivier, WFM Röling, B Teusink, FJ Bruggeman PloS one 8 (5), e64567, 2013	147	2013
How fast‐growing bacteria robustly tune their ribosome concentration to approximate growth‐rate maximization E Bosdriesz, D Molenaar, B Teusink, FJ Bruggeman The FEBS journal 282 (10), 2029-2044, 2015	139	2015
Calcium sensing receptor signalling in physiology and cancer SC Brennan, U Thiem, S Roth, A Aggarwal, IS Fetahu, S Tennakoon, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1833 (7), 1732-1744, 2013	137	2013
Elongation dynamics shape bursty transcription and translation M Dobrzyński, FJ Bruggeman Proceedings of the National Academy of Sciences 106 (8), 2583-2588, 2009	128	2009
Systems biology towards life in silico: mathematics of the control of living cells HV Westerhoff, A Kolodkin, R Conradie, SJ Wilkinson, FJ Bruggeman, ... Journal of mathematical biology 58 (1), 7-34, 2009	99	2009
The volumes and transcript counts of single cells reveal concentration homeostasis and capture biological noise H Kempe, A Schwabe, F Crémazy, PJ Verschure, FJ Bruggeman Molecular biology of the cell 26 (4), 797-804, 2015	94	2015
Systems biology: the elements and principles of life HV Westerhoff, C Winder, H Messiha, E Simeonidis, M Adamczyk, ... FEBS letters 583 (24), 3882-3890, 2009	90	2009
Noise management by molecular networks FJ Bruggeman, N Blüthgen, HV Westerhoff PLoS computational biology 5 (9), e1000506, 2009	89	2009
Optimal flux spaces of genome-scale stoichiometric models are determined by a few subnetworks SM Kelk, BG Olivier, L Stougie, FJ Bruggeman Scientific reports 2 (1), 1-7, 2012	86	2012

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