Identification of a novel mode of complement activation on stimulated platelets mediated by properdin and C3 (H2O) G Saggu, C Cortes, HN Emch, G Ramirez, RG Worth, VP Ferreira The Journal of Immunology 190 (12), 6457-6467, 2013 | 97 | 2013 |
Local release of properdin in the cellular microenvironment: role in pattern recognition and amplification of the alternative pathway of complement C Cortes, JA Ohtola, G Saggu, VP Ferreira Frontiers in immunology 3, 412, 2013 | 93 | 2013 |
Protection from septic peritonitis by rapid neutrophil recruitment through omental high endothelial venules K Buscher, H Wang, X Zhang, P Striewski, B Wirth, G Saggu, ... Nature communications 7 (1), 10828, 2016 | 72 | 2016 |
Low-dose recombinant properdin provides substantial protection against Streptococcus pneumoniae and Neisseria meningitidis infection YM Ali, A Hayat, BM Saeed, KS Haleem, S Alshamrani, HI Kenawy, ... Proceedings of the National Academy of Sciences 111 (14), 5301-5306, 2014 | 56 | 2014 |
Cis interaction between sialylated FcγRIIA and the αI-domain of Mac-1 limits antibody-mediated neutrophil recruitment G Saggu, K Okubo, Y Chen, R Vattepu, N Tsuboi, F Rosetti, X Cullere, ... Nature communications 9 (1), 5058, 2018 | 51 | 2018 |
Neutrophil FcγRIIA promotes IgG-mediated glomerular neutrophil capture via Abl/Src kinases H Nishi, K Furuhashi, X Cullere, G Saggu, MJ Miller, Y Chen, F Rosetti, ... The Journal of clinical investigation 127 (10), 3810-3826, 2017 | 49 | 2017 |
Properdin-mediated C5a production enhances stable binding of platelets to granulocytes in human whole blood AZ Blatt, G Saggu, KV Kulkarni, C Cortes, JM Thurman, D Ricklin, ... The Journal of Immunology 196 (11), 4671-4680, 2016 | 34 | 2016 |
Increased lymphocyte activation and atherosclerosis in CD47-deficient mice D Engelbertsen, A Autio, RAF Verwilligen, MAC Depuydt, G Newton, ... Scientific Reports 9 (1), 10608, 2019 | 32 | 2019 |
PKC-δ activation in neutrophils promotes fungal clearance X Li, X Cullere, H Nishi, G Saggu, E Durand, MK Mansour, JM Tam, ... Journal of Leucocyte Biology 100 (3), 581-588, 2016 | 32 | 2016 |
ATF3 and CH25H regulate effector trogocytosis and anti-tumor activities of endogenous and immunotherapeutic cytotoxic T lymphocytes Z Lu, N McBrearty, J Chen, VS Tomar, H Zhang, G De Rosa, A Tan, ... Cell metabolism 34 (9), 1342-1358. e7, 2022 | 21 | 2022 |
Factor H C-terminal domains are critical for regulation of platelet/granulocyte aggregate formation AZ Blatt, G Saggu, C Cortes, AP Herbert, D Kavanagh, D Ricklin, ... Frontiers in immunology 8, 305027, 2017 | 20 | 2017 |
Protection of regulatory T cells from fragility and inactivation in the tumor microenvironment H Zhang, VS Tomar, J Li, R Basavaraja, F Yan, J Gui, N McBrearty, ... Cancer immunology research 10 (12), 1490-1505, 2022 | 5 | 2022 |
The Role of Properdin in Killing of Non-Pathogenic Leptospira biflexa APG Martinez, PAE Abreu, S de Arruda Vasconcellos, PL Ho, VP Ferreira, ... Frontiers in Immunology 11, 572562, 2020 | 5 | 2020 |
Inhibitory affinity modulation of FcγRIIA ligand binding by glycosphingolipids by inside-out signaling K Okubo, MD Brenner, X Cullere, G Saggu, ML Patchen, N Bose, S Mihori, ... Cell reports 35 (7), 2021 | 4 | 2021 |
Humoral Pathogenesis: Fcγ Receptors in Autoimmunity and End-Organ Damage T Ernandez, G Saggu, TN Mayadas Systemic lupus erythematosus, 159-184, 2016 | 2 | 2016 |
Role of complement regulatory protein properdin in complement activation on platelets and in the formation of platelet-leukocyte aggregates G Saggu The University of Toledo, 2014 | 2 | 2014 |
Identification of a novel mode of complement activation on stimulated platelets mediated by properdin G Saggu, C Cortes, HN Emch, G Ramirez, RG Worth, VP Ferreira Immunobiology 11 (217), 1175-1176, 2012 | 1 | 2012 |
The Role of Properdin in Killing of APG Martinez, PAE Abreu, S de Arruda Vasconcellos, PL Ho, VP Ferreira, ... The Role of Complement in Microbial Infections, 2021 | | 2021 |
Fcγ receptors in autoimmunity and end-organ damage T Ernandez, K Okubo, G Saggu, TN Mayadas Systemic Lupus Erythematosus, 179-195, 2021 | | 2021 |
PKC-δ activation in neutrophils promotes fungal clearance. LX Li Xun, X Cullere, H Nishi, G Saggu, E Durand, MK Mansour, JM Tam, ... | | 2016 |