Molecular effects of ER alpha-and beta-selective agonists on regulation of energy homeostasis in obese female Wistar rats C Weigt, T Hertrampf, FM Kluxen, U Flenker, F Hülsemann, ... Molecular and cellular endocrinology 377 (1-2), 147-158, 2013 | 85 | 2013 |
ERβ-specific agonists and genistein inhibit proliferation and induce apoptosis in the large and small intestine B Schleipen, T Hertrampf, KH Fritzemeier, FM Kluxen, A Lorenz, ... Carcinogenesis 32 (11), 1675-1683, 2011 | 67 | 2011 |
Cadmium modulates expression of aryl hydrocarbon receptor-associated genes in rat uterus by interaction with the estrogen receptor FM Kluxen, N Höfer, G Kretzschmar, GH Degen, P Diel Archives of toxicology 86, 591-601, 2012 | 56 | 2012 |
Investigations on the estrogenic activity of the metallohormone cadmium in the rat intestine N Höfer, P Diel, J Wittsiepe, M Wilhelm, FM Kluxen, GH Degen Archives of toxicology 84, 541-552, 2010 | 51 | 2010 |
A review of recent advances in benchmark dose methodology SM Jensen, FM Kluxen, C Ritz Risk Analysis 39 (10), 2295-2315, 2019 | 50 | 2019 |
Lifelong exposure to dietary isoflavones reduces risk of obesity in ovariectomized Wistar rats A Kurrat, T Blei, FM Kluxen, DR Mueller, M Piechotta, ST Soukup, ... Molecular nutrition & food research 59 (12), 2407-2418, 2015 | 37 | 2015 |
Genistein modulates the anti-tumor activity of cisplatin in MCF-7 breast and HT-29 colon cancer cells XJ Hu, MY Xie, FM Kluxen, P Diel Archives of toxicology 88, 625-635, 2014 | 36 | 2014 |
The metallohormone cadmium modulates AhR-associated gene expression in the small intestine of rats similar to ethinyl-estradiol FM Kluxen, P Diel, N Höfer, E Becker, GH Degen Archives of toxicology 87, 633-643, 2013 | 29 | 2013 |
Using historical control data in bioassays for regulatory toxicology FM Kluxen, K Weber, C Strupp, SM Jensen, LA Hothorn, JC Garcin, ... Regulatory Toxicology and Pharmacology 125, 105024, 2021 | 24 | 2021 |
Assessment of an extended dataset of in vitro human dermal absorption studies on pesticides to determine default values, opportunities for read-across and influence of dilution … M Aggarwal, P Fisher, A Hüser, FM Kluxen, R Parr-Dobrzanski, M Soufi, ... Regulatory Toxicology and Pharmacology 72 (1), 58-70, 2015 | 24 | 2015 |
Alternatives to statistical decision trees in regulatory (eco-) toxicological bioassays FM Kluxen, LA Hothorn Archives of toxicology 94 (4), 1135-1149, 2020 | 21 | 2020 |
Compounded conservatism in European re-entry worker risk assessment of pesticides FM Kluxen, E Felkers, J Baumann, N Morgan, C Wiemann, F Stauber, ... Regulatory Toxicology and Pharmacology, 104864, 2021 | 20 | 2021 |
bmd: an R package for benchmark dose estimation SM Jensen, FM Kluxen, JC Streibig, N Cedergreen, C Ritz PeerJ 8, e10557, 2020 | 20 | 2020 |
Robust multiple comparisons against a control group with application in toxicology LA Hothorn, FM Kluxen https://arxiv.org/abs/1905.01838, 2019 | 14 | 2019 |
" New statistics" in regulatory toxicology? FM Kluxen Regul. Toxicol. Pharmacol. 117, 104763, 2020 | 12 | 2020 |
Scatter plotting as a simple tool to analyse relative organ to body weight in toxicological bioassays FM Kluxen Archives of toxicology 93 (8), 2409-2420, 2019 | 12 | 2019 |
Metribuzin-induced non-adverse liver changes result in rodent-specific non-adverse thyroid effects via uridine 5′-diphospho-glucuronosyltransferase (UDPGT, UGT) modulation W Bomann, H Tinwell, P Jenkinson, FM Kluxen Regulatory Toxicology and Pharmacology 122, 104884, 2021 | 11 | 2021 |
Dermal absorption study OECD TG 428 mass balance recommendations based on the EFSA database FM Kluxen, S Grégoire, A Schepky, NJ Hewitt, M Klaric, JY Domoradzki, ... Regulatory Toxicology and Pharmacology 108, 104475, 2019 | 9 | 2019 |
Sub-structure-based category formation for the prioritisation of genotoxicity hazard assessment for pesticide residues: Sulphonyl ureas SJ Enoch, Z Hasarova, MTD Cronin, K Bridgwood, S Rao, FM Kluxen, ... Regulatory Toxicology and Pharmacology 129, 105115, 2022 | 8 | 2022 |
Expanding the toxicologist's statistical toolbox: using effect size estimation and dose-response modelling for holistic assessments instead of generic testing FM Kluxen, SM Jensen Regulatory Toxicology and Pharmacology 121, 104871, 2021 | 8 | 2021 |