Follow
Dr Menuka Karki
Dr Menuka Karki
Harvard Medical School, Harvard University
Verified email at hms.harvard.edu
Title
Cited by
Cited by
Year
Comprehensive molecular characterization identifies distinct genomic and immune hallmarks of renal medullary carcinoma
P Msaouel, GG Malouf, X Su, H Yao, DN Tripathi, M Soeung, J Gao, ...
Cancer Cell 37 (5), 720-734. e13, 2020
882020
Exploring natural product chemistry and biology with multicomponent reactions. 5. Discovery of a novel tubulin-targeting scaffold derived from the rigidin family of marine …
LV Frolova, IV Magedov, AE Romero, M Karki, I Otero, K Hayden, ...
Journal of medicinal chemistry 56 (17), 6886-6900, 2013
602013
SETD2 Haploinsufficiency for Microtubule Methylation Is an Early Driver of Genomic Instability in Renal Cell Carcinoma
YC Chiang, IY Park, EA Terzo, DN Tripathi, FM Mason, CC Fahey, M Karki, ...
Cancer research 78 (12), 3135-3146, 2018
562018
Precocious centriole disengagement and centrosome fragmentation induced by mitotic delay
M Karki, N Keyhaninejad, CB Shuster
Nature communications 8 (1), 15803, 2017
402017
The Huntingtin-interacting protein SETD2/HYPB is an actin lysine methyltransferase
RNH Seervai, RK Jangid, M Karki, DN Tripathi, SY Jung, SE Kearns, ...
Science advances 6 (40), eabb7854, 2020
332020
Synthetic and Biological Studies of Tubulin Targeting C2‐Substituted 7‐Deazahypoxanthines Derived from Marine Alkaloid Rigidins
R Scott, M Karki, MR Reisenauer, R Rodrigues, R Dasari, WR Smith, ...
ChemMedChem 9 (7), 1428-1435, 2014
332014
Somatic mutations in planar cell polarity genes in neural tissue from human fetuses with neural tube defects
T Tian, Y Lei, Y Chen, M Karki, L Jin, RH Finnell, L Wang, A Ren
Human genetics 139, 1299-1314, 2020
242020
A cytoskeletal function for PBRM1 reading methylated microtubules
M Karki, RK Jangid, R Anish, RNH Seervai, JP Bertocchio, T Hotta, ...
Science advances 7 (14), eabf2866, 2021
222021
Neuronal SETD2 activity links microtubule methylation to an anxiety-like phenotype in mice
M Koenning, X Wang, M Karki, RK Jangid, S Kearns, DN Tripathi, ...
Brain 144 (8), 2527-2540, 2021
132021
Reengineered epipodophyllotoxin
IV Magedov, NM Evdokimov, M Karki, AS Peretti, DT Lima, LV Frolova, ...
Chemical communications 48 (84), 10416-10418, 2012
112012
Bexarotene – a novel modulator of AURKA and the primary cilium in VHL-deficient cells
P Chowdhury, RT Powell, C Stephan, IP Uray, T Talley, M Karki, ...
Journal of cell science 131 (24), jcs219923, 2018
82018
FKBP8 variants are risk factors for spina bifida
T Tian, X Cao, SE Kim, YL Lin, JW Steele, RM Cabrera, M Karki, W Yang, ...
Human molecular genetics 29 (18), 3132-3144, 2020
42020
Neddylation inhibition sensitises renal medullary carcinoma tumours to platinum chemotherapy
DD Shapiro, NM Zacharias, DN Tripathi, M Karki, JP Bertocchio, ...
Clinical and Translational Medicine 13 (5), e1267, 2023
32023
CIC missense variants contribute to susceptibility for spina bifida
X Han, X Cao, V Aguiar‐Pulido, W Yang, M Karki, PAP Ramirez, ...
Human mutation 43 (12), 2021-2032, 2022
22022
SETD2 is an actin lysine methyltransferase
RNH Seervai, RK Jangid, M Karki, DN Tripathi, SY Jung, SE Kearns, ...
bioRxiv, 2020.04. 13.034629, 2020
12020
Direct detection of rpoB and katG gene mutations of Mycobacterium tuberculosis in clinical samples
S Pandey, A Lamichhane, A Byanjankar, A Kharel, C Rai, SP Lekhak, ...
Asian Pacific Journal of Tropical Biomedicine 7 (8), 698-701, 2017
12017
Hyperprogression due to myeloid mimicry in renal medullary carcinoma treated with nivolumab plus ipilimumab
M Soeung, X Yan, L Zhang, L Perelli, J Chen, BS Tidwell, H Khan, CN Le, ...
Cancer Research 84 (6_Supplement), 2702-2702, 2024
2024
A cytoskeletal function for PBRM1: reading methylated microtubules to maintain genomic stability
M Karki, R Jangid, R Anish, RN Seervai, JP Bertocchio, T Hotta, ...
Cancer Research 81 (13_Supplement), 2042-2042, 2021
2021
Regulation of Mitotic Centrosome Integrity and Cytokinesis in Cultured Human Cells
M Karki
New Mexico State University, 2017
2017
Prolonged prometaphase arrest induces centriole disengagement and centrosome fragmentation in cultured human cells.
M Karki, N Keyhaninejad, CB Shuster
MOLECULAR BIOLOGY OF THE CELL 26, 2015
2015
The system can't perform the operation now. Try again later.
Articles 1–20