| Mass spectrometry-based metabolomics: a guide for annotation, quantification and best reporting practices S Alseekh, A Aharoni, Y Brotman, K Contrepois, J D’Auria, J Ewald, ... Nature methods 18 (7), 747-756, 2021 | 462 | 2021 |
| Systematic identification of allosteric protein-metabolite interactions that control enzyme activity in vivo H Link, K Kochanowski, U Sauer Nature biotechnology 31 (4), 357-361, 2013 | 266 | 2013 |
| Real-time metabolome profiling of the metabolic switch between starvation and growth H Link, T Fuhrer, L Gerosa, N Zamboni, U Sauer Nature methods 12 (11), 1091-1097, 2015 | 242 | 2015 |
| Transcriptional regulation is insufficient to explain substrate‐induced flux changes in Bacillus subtilis V Chubukov, M Uhr, L Le Chat, RJ Kleijn, M Jules, H Link, S Aymerich, ... Molecular systems biology 9 (1), 709, 2013 | 205 | 2013 |
| Reserve flux capacity in the pentose phosphate pathway enables Escherichia coli's rapid response to oxidative stress D Christodoulou, H Link, T Fuhrer, K Kochanowski, L Gerosa, U Sauer Cell systems 6 (5), 569-578. e7, 2018 | 184 | 2018 |
| Advancing metabolic models with kinetic information H Link, D Christodoulou, U Sauer Current opinion in biotechnology 29, 8-14, 2014 | 120 | 2014 |
| Evaluation of artificial neural networks for modelling and optimization of medium composition with a genetic algorithm E Franco-Lara, H Link, D Weuster-Botz Process Biochemistry 41 (10), 2200-2206, 2006 | 100 | 2006 |
| Growth-rate dependent resource investment in bacterial motile behavior quantitatively follows potential benefit of chemotaxis B Ni, R Colin, H Link, RG Endres, V Sourjik Proceedings of the National Academy of Sciences 117 (1), 595-601, 2020 | 92 | 2020 |
| Allosteric feedback inhibition enables robust amino acid biosynthesis in E. coli by enforcing enzyme overabundance T Sander, N Farke, C Diehl, M Kuntz, T Glatter, H Link Cell systems 8 (1), 66-75. e8, 2019 | 91 | 2019 |
| Systematic identification of metabolites controlling gene expression in E. coli M Lempp, N Farke, M Kuntz, SA Freibert, R Lill, H Link Nature communications 10 (1), 4463, 2019 | 88 | 2019 |
| Leakage of adenylates during cold methanol/glycerol quenching of Escherichia coli H Link, B Anselment, D Weuster-Botz Metabolomics 4, 240-247, 2008 | 80 | 2008 |
| Breakdown of Vibrio cholerae biofilm architecture induced by antibiotics disrupts community barrier function F Díaz-Pascual, R Hartmann, M Lempp, L Vidakovic, B Song, H Jeckel, ... Nature microbiology 4 (12), 2136-2145, 2019 | 75 | 2019 |
| Time-optimized isotope ratio LC–MS/MS for high-throughput quantification of primary metabolites JC Guder, T Schramm, T Sander, H Link Analytical Chemistry 89 (3), 1624-1631, 2017 | 64 | 2017 |
| A dynamic pathway analysis approach reveals a limiting futile cycle in N-acetylglucosamine overproducing Bacillus subtilis Y Liu, H Link, L Liu, G Du, J Chen, U Sauer Nature communications 7 (1), 11933, 2016 | 58 | 2016 |
| Multi-omics analysis of CRISPRi-knockdowns identifies mechanisms that buffer decreases of enzymes in E. coli metabolism S Donati, M Kuntz, V Pahl, N Farke, D Beuter, T Glatter, JV Gomes-Filho, ... Cell systems 12 (1), 56-67. e6, 2021 | 57 | 2021 |
| Genetic algorithm for multi-objective experimental optimization H Link, D Weuster-Botz Bioprocess and biosystems engineering 29, 385-390, 2006 | 52 | 2006 |
| Quorum sensing and metabolic state of the host control lysogeny-lysis switch of bacteriophage T1 L Laganenka, T Sander, A Lagonenko, Y Chen, H Link, V Sourjik MBio 10 (5), 10.1128/mbio. 01884-19, 2019 | 50 | 2019 |
| Adaptation of Bacillus subtilis to Life at Extreme Potassium Limitation J Gundlach, C Herzberg, D Hertel, A Thürmer, R Daniel, H Link, J Stülke MBio 8 (4), 10.1128/mbio. 00861-17, 2017 | 49 | 2017 |
| Spatial alanine metabolism determines local growth dynamics of Escherichia coli colonies F Díaz-Pascual, M Lempp, K Nosho, H Jeckel, JK Jo, K Neuhaus, ... Elife 10, e70794, 2021 | 43 | 2021 |
| Metabolism of non-growing bacteria M Lempp, P Lubrano, G Bange, H Link Biological Chemistry 401 (12), 1479-1485, 2020 | 43 | 2020 |
