Broad-spectrum antivirals against 3C or 3C-like proteases of picornaviruses, noroviruses, and coronaviruses Y Kim, S Lovell, KC Tiew, SR Mandadapu, KR Alliston, KP Battaile, ... Journal of virology 86 (21), 11754-11762, 2012 | 362 | 2012 |
Potent inhibition of feline coronaviruses with peptidyl compounds targeting coronavirus 3C-like protease Y Kim, SR Mandadapu, WC Groutas, KO Chang Antiviral research 97 (2), 161-168, 2013 | 86 | 2013 |
Potent inhibition of norovirus 3CL protease by peptidyl α-ketoamides and α-ketoheterocycles SR Mandadapu, PM Weerawarna, MR Gunnam, KR Alliston, ... Bioorganic & medicinal chemistry letters 22 (14), 4820-4826, 2012 | 77 | 2012 |
Design, synthesis, and evaluation of inhibitors of Norwalk virus 3C protease KC Tiew, G He, S Aravapalli, SR Mandadapu, MR Gunnam, KR Alliston, ... Bioorganic & medicinal chemistry letters 21 (18), 5315-5319, 2011 | 67 | 2011 |
Structure-guided design and optimization of dipeptidyl inhibitors of norovirus 3CL protease. Structure–activity relationships and biochemical, X-ray crystallographic, cell … AC Galasiti Kankanamalage, Y Kim, PM Weerawarna, RAZ Uy, ... Journal of medicinal chemistry 58 (7), 3144-3155, 2015 | 66 | 2015 |
Macrocyclic inhibitors of 3C and 3C-like proteases of picornavirus, norovirus, and coronavirus SR Mandadapu, PM Weerawarna, AM Prior, RAZ Uy, S Aravapalli, ... Bioorganic & medicinal chemistry letters 23 (13), 3709-3712, 2013 | 59 | 2013 |
Inhibition of norovirus 3CL protease by bisulfite adducts of transition state inhibitors SR Mandadapu, MR Gunnam, KC Tiew, RAZ Uy, AM Prior, KR Alliston, ... Bioorganic & medicinal chemistry letters 23 (1), 62-65, 2013 | 58 | 2013 |
Inhibition of noroviruses by piperazine derivatives D Dou, G He, SR Mandadapu, S Aravapalli, Y Kim, KO Chang, ... Bioorganic & medicinal chemistry letters 22 (1), 377-379, 2012 | 56 | 2012 |
Antifungal activity of a series of 1, 2-benzisothiazol-3 (2H)-one derivatives D Dou, D Alex, B Du, KC Tiew, S Aravapalli, SR Mandadapu, ... Bioorganic & medicinal chemistry 19 (19), 5782-5787, 2011 | 41 | 2011 |
Potent inhibition of norovirus by dipeptidyl α-hydroxyphosphonate transition state mimics SR Mandadapu, MR Gunnam, ACG Kankanamalage, RAZ Uy, KR Alliston, ... Bioorganic & medicinal chemistry letters 23 (21), 5941-5944, 2013 | 36 | 2013 |
Potent inhibition of Norwalk virus by cyclic sulfamide derivatives D Dou, KC Tiew, G He, SR Mandadapu, S Aravapalli, KR Alliston, Y Kim, ... Bioorganic & medicinal chemistry 19 (20), 5975-5983, 2011 | 35 | 2011 |
Cyclosulfamide-based derivatives as inhibitors of noroviruses D Dou, SR Mandadapu, KR Alliston, Y Kim, KO Chang, WC Groutas European journal of medicinal chemistry 47, 59-64, 2012 | 33 | 2012 |
Design and synthesis of inhibitors of noroviruses by scaffold hopping D Dou, SR Mandadapu, KR Alliston, Y Kim, KO Chang, WC Groutas Bioorganic & medicinal chemistry 19 (19), 5749-5755, 2011 | 33 | 2011 |
Potent norovirus inhibitors based on the acyclic sulfamide scaffold D Dou, KC Tiew, SR Mandadapu, MR Gunnam, KR Alliston, Y Kim, ... Bioorganic & medicinal chemistry 20 (6), 2111-2118, 2012 | 25 | 2012 |
A new natural product analog of blasticidin S reveals cellular uptake facilitated by the NorA multidrug transporter JR Davison, KM Lohith, X Wang, K Bobyk, SR Mandadapu, SL Lee, ... Antimicrobial agents and chemotherapy 61 (6), 10.1128/aac. 02635-16, 2017 | 18 | 2017 |
Catalyst-and Solvent-Free Synthesis of α-Amino Polyfluoroalkylphosphonates from Bis (fluoroalkyl) Phosphonates and Aldimines SN Arbuzova, NK Gusarova, TI Kazantseva, SI Verkhoturova, ... Synthesis 52 (10), 1531-1540, 2020 | 9 | 2020 |
Design of HIV coreceptor derived peptides that inhibit viral entry at submicromolar concentrations KD Bobyk, SR Mandadapu, K Lohith, C Guzzo, A Bhargava, P Lusso, ... Molecular pharmaceutics 14 (8), 2681-2689, 2017 | 8 | 2017 |
Design and synthesis of small molecule-sulfotyrosine mimetics that inhibit HIV-1 entry C Dogo-Isonagie, SL Lee, K Lohith, H Liu, SR Mandadapu, S Lusvarghi, ... Bioorganic & medicinal chemistry 24 (8), 1718-1728, 2016 | 8 | 2016 |
Uncovering the biosynthetic origins of cyclic phenolic natural products in pelagophyte algae. J Davison, S Mandadapu, C Bewley Natural Product Discovery and Development in the Genomic Era, 2018 | | 2018 |
Design of HIV co-receptor derived peptides that inhibit viral entry at submicromolar concentrations SR Mandadapu, K Bobyk, K Lohith, C Bewley ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 254, 2017 | | 2017 |