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James J Douglas
James J Douglas
Verified email at astrazeneca.com
Title
Cited by
Cited by
Year
A scalable and operationally simple radical trifluoromethylation
JW Beatty, JJ Douglas, KP Cole, CRJ Stephenson
Nature communications 6, 2015
3582015
Photoinduced Remote Functionalizations via Iminyl Radical‐Promoted C‐C and C‐H Bond Cleavage Cascades.
EM Dauncey, SP Marcillo, JJ Douglas, NS Sheikh, D Leonori
Angewandte Chemie International Edition, 2017
3462017
Visible light photocatalysis: applications and new disconnections in the synthesis of pharmaceutical agents
JJ Douglas, MJ Sevrin, CRJ Stephenson
Organic Process Research & Development 20 (7), 1134-1147, 2016
3462016
NHCs in asymmetric organocatalysis: recent advances in azolium enolate generation and reactivity
J Douglas, G Churchill, AD Smith
Synthesis 44 (15), 2295-2309, 2012
2882012
Hydroxylamine Derivatives as Nitrogen‐Radical Precursors in Visible‐Light Photochemistry
J Davies, SP Morcillo, JJ Douglas, D Leonori
Chemistry–A European Journal, 2018
2362018
Photochemical Perfluoroalkylation with Pyridine N-Oxides: Mechanistic Insights and Performance on a Kilogram Scale
JW Beatty, JJ Douglas, R Miller, RC McAtee, KP Cole, CRJ Stephenson
Chem 1 (3), 456-472, 2016
2272016
Photoinduced Remote Functionalization of Amides and Amines Using Electrophilic Nitrogen Radicals
SP Morcillo, EM Dauncey, JH Kim, JJ Douglas, NS Sheikh, D Leonori
Angewandte Chemie International Edition, 2018
2122018
Photocatalysis in the Life Science Industry
L Candish, KD Collins, GC Cook, JJ Douglas, A Gómez-Suárez, A Jolit, ...
Chemical Reviews, 2021
2112021
Practical and regioselective amination of arenes using alkyl amines
A Ruffoni, F Juliá, TD Svejstrup, AJ McMillan, JJ Douglas, D Leonori
Nature chemistry, 1, 2019
1962019
A Visible‐Light‐Mediated Radical Smiles Rearrangement and its Application to the Synthesis of a Difluoro‐Substituted Spirocyclic ORL‐1 Antagonist
JJ Douglas, H Albright, MJ Sevrin, KP Cole, CRJ Stephenson
Angewandte Chemie International Edition 54 (49), 14898-14902, 2015
1632015
A photochemical dehydrogenative strategy for aniline synthesis
SU Dighe, F Juliá, A Luridiana, JJ Douglas, D Leonori
Nature 584 (7819), 75-81, 2020
1312020
Isothiourea-mediated asymmetric Michael-lactonisation of trifluoromethylenones: a synthetic and mechanistic study
LC Morrill, J Douglas, T Lebl, AMZ Slawin, DJ Fox, AD Smith
Chemical Science 4 (11), 4146-4155, 2013
1232013
Ligand functionalization as a deactivation pathway in a fac-Ir (ppy) 3-mediated radical addition
JJ Devery III, JJ Douglas, JD Nguyen, KP Cole, RA Flowers II, ...
Chemical Science 6 (1), 537-541, 2015
1082015
Isothiourea-catalyzed asymmetric synthesis of β-lactams and β-amino esters from arylacetic acid derivatives and N-sulfonylaldimines
SR Smith, J Douglas, H Prevet, P Shapland, AMZ Slawin, AD Smith
The Journal of organic chemistry 79 (4), 1626-1639, 2014
932014
Photoredox Catalysis in a Complex Pharmaceutical Setting: Toward the Preparation of JAK2 Inhibitor LY2784544
JJ Douglas, KP Cole, CRJ Stephenson
The Journal of organic chemistry 79 (23), 11631-11643, 2014
902014
Copper-catalysed amination of alkyl iodides enabled by halogen-atom transfer
B Górski, AL Barthelemy, JJ Douglas, F Juliá, D Leonori
Nature Catalysis, 1-8, 2021
892021
NHC-Promoted asymmetric β-lactone formation from arylalkylketenes and electron-deficient benzaldehydes or pyridinecarboxaldehydes
J Douglas, JE Taylor, G Churchill, AMZ Slawin, AD Smith
The Journal of organic chemistry 78 (8), 3925-3938, 2013
752013
A Dual Photoredox-Nickel Strategy for Remote Functionalization via Iminyl Radicals: Radical Ring-Opening–Arylation,–Vinylation and–Alkylation Cascades
E Dauncey, SU Dighe, JJ Douglas, D Leonori
Chemical Science, 2019
742019
Stereospecific asymmetric N-heterocyclic carbene (NHC)-catalyzed redox synthesis of trifluoromethyl dihydropyranones and mechanistic insights
AT Davies, JE Taylor, J Douglas, CJ Collett, LC Morrill, C Fallan, ...
The Journal of organic chemistry 78 (18), 9243-9257, 2013
732013
Enabling Novel Photoredox Reactivity via Photocatalyst Selection
JJ Douglas, JD Nguyen, KP Cole, CRJ Stephenson
Aldrichimica Acta 47 (1), 15-25, 2014
572014
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