| Large shifts in pKa values of lysine residues buried inside a protein DG Isom, CA Castañeda, BR Cannon, B García-Moreno E Proceedings of the National Academy of Sciences 108 (13), 5260-5265, 2011 | 487 | 2011 |
| Ubiquitin modulates liquid-liquid phase separation of UBQLN2 via disruption of multivalent interactions TP Dao, RM Kolaitis, HJ Kim, K O’Donovan, B Martyniak, E Colicino, ... Molecular cell 69 (6), 965-978. e6, 2018 | 290 | 2018 |
| Charges in the hydrophobic interior of proteins DG Isom, CA Castañeda, BR Cannon, PD Velu, B García-Moreno E Proceedings of the National Academy of Sciences 107 (37), 16096-16100, 2010 | 255 | 2010 |
| Molecular determinants of the pKa values of Asp and Glu residues in staphylococcal nuclease CA Castaneda, CA Fitch, A Majumdar, V Khangulov, JL Schlessman, ... Proteins: Structure, Function, and Bioinformatics 77 (3), 570-588, 2009 | 180 | 2009 |
| High tolerance for ionizable residues in the hydrophobic interior of proteins DG Isom, BR Cannon, CA Castañeda, A Robinson, B García-Moreno E Proceedings of the National Academy of Sciences 105 (46), 17784-17788, 2008 | 165 | 2008 |
| Mapping and initial analysis of human subtelomeric sequence assemblies H Riethman, A Ambrosini, C Castaneda, J Finklestein, XL Hu, U Mudunuri, ... Genome research 14 (1), 18-28, 2004 | 158 | 2004 |
| The pKa values of acidic and basic residues buried at the same internal location in a protein are governed by different factors MJ Harms, CA Castañeda, JL Schlessman, GR Sue, DG Isom, ... Journal of molecular biology 389 (1), 34-47, 2009 | 155 | 2009 |
| Recovering a representative conformational ensemble from underdetermined macromolecular structural data K Berlin, CA Castaneda, D Schneidman-Duhovny, A Sali, A Nava-Tudela, ... Journal of the American Chemical Society 135 (44), 16595-16609, 2013 | 120 | 2013 |
| Nonenzymatic assembly of natural polyubiquitin chains of any linkage composition and isotopic labeling scheme C Castañeda, J Liu, A Chaturvedi, U Nowicka, TA Cropp, D Fushman Journal of the American Chemical Society 133 (44), 17855-17868, 2011 | 101 | 2011 |
| ALS-linked mutations affect UBQLN2 oligomerization and phase separation in a position-and amino acid-dependent manner TP Dao, B Martyniak, AJ Canning, Y Lei, EG Colicino, MS Cosgrove, ... Structure 27 (6), 937-951. e5, 2019 | 84 | 2019 |
| DNA-damage-inducible 1 protein (Ddi1) contains an uncharacteristic ubiquitin-like domain that binds ubiquitin U Nowicka, D Zhang, O Walker, D Krutauz, CA Castañeda, A Chaturvedi, ... Structure 23 (3), 542-557, 2015 | 79 | 2015 |
| Unique structural, dynamical, and functional properties of k11-linked polyubiquitin chains CA Castañeda, TR Kashyap, MA Nakasone, S Krueger, D Fushman Structure 21 (7), 1168-1181, 2013 | 78 | 2013 |
| Linkage via K27 bestows ubiquitin chains with unique properties among polyubiquitins CA Castaneda, EK Dixon, O Walker, A Chaturvedi, MA Nakasone, ... Structure 24 (3), 423-436, 2016 | 64 | 2016 |
| Linkage-specific conformational ensembles of non-canonical polyubiquitin chains CA Castañeda, A Chaturvedi, CM Camara, JE Curtis, S Krueger, ... Physical Chemistry Chemical Physics 18 (8), 5771-5788, 2016 | 63 | 2016 |
| Direct evidence for deprotonation of a lysine side chain buried in the hydrophobic core of a protein Y Takayama, CA Castañeda, M Chimenti, B García-Moreno, J Iwahara Journal of the American Chemical Society 130 (21), 6714-6715, 2008 | 63 | 2008 |
| Single amino acid substitutions in stickers, but not spacers, substantially alter UBQLN2 phase transitions and dense phase material properties Y Yang, HB Jones, TP Dao, CA Castañeda The Journal of Physical Chemistry B 123 (17), 3618-3629, 2019 | 61 | 2019 |
| Structural origins of high apparent dielectric constants experienced by ionizable groups in the hydrophobic core of a protein MS Chimenti, CA Castañeda, A Majumdar Journal of molecular biology 405 (2), 361-377, 2011 | 47 | 2011 |
| Structural and thermodynamic consequences of burial of an artificial ion pair in the hydrophobic interior of a protein AC Robinson, CA Castañeda, JL Schlessman, B García-Moreno E Proceedings of the National Academy of Sciences 111 (32), 11685-11690, 2014 | 41 | 2014 |
| Nonenzymatic assembly of branched polyubiquitin chains for structural and biochemical studies EK Dixon, CA Castañeda, TR Kashyap, Y Wang, D Fushman Bioorganic & medicinal chemistry 21 (12), 3421-3429, 2013 | 41 | 2013 |
| Controlled enzymatic synthesis of natural-linkage, defined-length polyubiquitin chains using lysines with removable protecting groups CA Castañeda, J Liu, TR Kashyap, RK Singh, D Fushman, TA Cropp Chemical communications 47 (7), 2026-2028, 2011 | 37 | 2011 |
David FushmanVerified email at umd.edu
