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ALI EL-KASABY
ALI EL-KASABY
Medical university of Vienna Austria
Verified email at meduniwien.ac.at
Title
Cited by
Cited by
Year
The serotonin transporter is an exclusive client of the coat protein complex II (COPII) component SEC24C
S Sucic, A El-Kasaby, O Kudlacek, S Sarker, HH Sitte, P Marin, ...
Journal of Biological Chemistry 286 (18), 16482-16490, 2011
1112011
Mutations in the carboxyl-terminal SEC24 binding motif of the serotonin transporter impair folding of the transporter
A El-Kasaby, H Just, E Malle, PC Stolt-Bergner, HH Sitte, M Freissmuth, ...
Journal of biological chemistry 285 (50), 39201-39210, 2010
752010
Switching the clientele
S Sucic, F Koban, A El-Kasaby, O Kudlacek, T Stockner, HH Sitte, ...
Journal of Biological Chemistry 288 (8), 5330-5341, 2013
612013
A salt bridge linking the first intracellular loop with the C terminus facilitates the folding of the serotonin transporter
F Koban, A El-Kasaby, C Häusler, T Stockner, BM Simbrunner, HH Sitte, ...
Journal of Biological Chemistry 290 (21), 13263-13278, 2015
482015
A cytosolic relay of heat shock proteins HSP70-1A and HSP90β monitors the folding trajectory of the serotonin transporter
A El-Kasaby, F Koban, HH Sitte, M Freissmuth, S Sucic
Journal of Biological Chemistry 289 (42), 28987-29000, 2014
482014
Pharmacochaperoning in a Drosophila model system rescues human dopamine transporter variants associated with infantile/juvenile parkinsonism
HMM Asjad, A Kasture, A El-Kasaby, M Sackel, T Hummel, M Freissmuth, ...
Journal of Biological Chemistry 292 (47), 19250-19265, 2017
432017
Functional Rescue of a Misfolded Drosophila melanogaster Dopamine Transporter Mutant Associated with a Sleepless Phenotype by Pharmacological Chaperones*♦
A Kasture, A El-Kasaby, D Szöllősi, HMM Asjad, A Grimm, T Stockner, ...
Journal of Biological Chemistry 291 (40), 20876-20890, 2016
412016
Functional and biochemical consequences of disease variants in neurotransmitter transporters: a special emphasis on folding and trafficking deficits
S Bhat, A El-Kasaby, M Freissmuth, S Sucic
Pharmacology & therapeutics 222, 107785, 2021
352021
Rescue by 4-phenylbutyrate of several misfolded creatine transporter-1 variants linked to the creatine transporter deficiency syndrome
A El-Kasaby, A Kasture, F Koban, M Hotka, HMM Asjad, H Kubista, ...
Neuropharmacology 161, 107572, 2019
342019
Conformational state interactions provide clues to the pharmacochaperone potential of serotonin transporter partial substrates
S Bhat, PS Hasenhuetl, A Kasture, A El-Kasaby, MH Baumann, ...
Journal of Biological Chemistry 292 (40), 16773-16786, 2017
312017
The creatine transporter unfolded: a knotty premise in the cerebral creatine deficiency syndrome
CV Farr, A El-Kasaby, M Freissmuth, S Sucic
Frontiers in Synaptic Neuroscience 12, 588954, 2020
302020
Tropane-based ibogaine analog rescues folding-deficient serotonin and dopamine transporters
S Bhat, DA Guthrie, A Kasture, A El-Kasaby, J Cao, A Bonifazi, T Ku, ...
ACS Pharmacology & Translational Science 4 (2), 503-516, 2020
212020
The N terminus specifies the switch between transport modes of the human serotonin transporter
C Kern, FA Erdem, A El-Kasaby, W Sandtner, M Freissmuth, S Sucic
Journal of Biological Chemistry 292 (9), 3603-3613, 2017
202017
Functional impact of the G279S substitution in the adenosine A1-receptor (A1R-G279S7. 44), a mutation associated with Parkinson’s disease
S Nasrollahi-Shirazi, D Szöllösi, Q Yang, E Muratspahic, A El-Kasaby, ...
Molecular pharmacology 98 (3), 250-266, 2020
162020
Binding and neutralization of C. difficile toxins A and B by purified clinoptilolite-tuff
C Ranftler, D Nagl, A Sparer, A Röhrich, M Freissmuth, A El-Kasaby, ...
PLoS One 16 (5), e0252211, 2021
132021
When transporters fail to be transported: how to rescue folding-deficient SLC6 transporters
S Sucic, A Kasture, HMM Asjad, C Kern, A El-Kasaby, M Freissmuth
Journal of neurology & neuromedicine 1 (9), 34, 2016
122016
Thermal unfolding of the human serotonin transporter: differential effect by stabilizing and destabilizing mutations and cholesterol on thermodynamic and kinetic stability
M Ponleitner, D Szöllősi, A El-Kasaby, F Koban, M Freissmuth, T Stockner
Molecular Pharmacology 101 (2), 95-105, 2022
82022
Cooperative binding of substrate and ions drives forward cycling of the human creatine transporter-1
CV Farr, A El-Kasaby, FA Erdem, S Sucic, M Freissmuth, W Sandtner
Frontiers in Physiology 13, 919439, 2022
52022
Drosophila melanogaster as a model for unraveling unique molecular features of epilepsy elicited by human GABA transporter 1 variants
AS Kasture, FP Fischer, L Kunert, ML Burger, AC Burgstaller, A El-Kasaby, ...
Frontiers in Neuroscience 16, 1074427, 2023
42023
(+)-Catharanthine and (-)-18-methoxycoronaridine induce antidepressant-like activity in mice by differently recruiting serotonergic and norepinephrinergic neurotransmission
HR Arias, P De Deurwaerdère, A El-Kasaby, G Di Giovanni, S Eom, ...
European Journal of Pharmacology 939, 175454, 2023
32023
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