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NIGEL GREIG
NIGEL GREIG
Chief, Drug Design & Development Section, National Institute on Aging, NIH
Verified email at grc.nia.nih.gov
Title
Cited by
Cited by
Year
Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease
EF Fang, Y Hou, K Palikaras, BA Adriaanse, JS Kerr, B Yang, S Lautrup, ...
Nature neuroscience 22 (3), 401-412, 2019
11472019
Selective butyrylcholinesterase inhibition elevates brain acetylcholine, augments learning and lowers Alzheimer β-amyloid peptide in rodent
NH Greig, T Utsuki, DK Ingram, Y Wang, G Pepeu, C Scali, QS Yu, ...
Proceedings of the National Academy of Sciences 102 (47), 17213-17218, 2005
7952005
Mitophagy and Alzheimer’s disease: cellular and molecular mechanisms
JS Kerr, BA Adriaanse, NH Greig, MP Mattson, MZ Cader, VA Bohr, ...
Trends in neurosciences 40 (3), 151-166, 2017
6652017
Exenatide once weekly versus placebo in Parkinson's disease: a randomised, double-blind, placebo-controlled trial
D Athauda, K Maclagan, SS Skene, M Bajwa-Joseph, D Letchford, ...
The Lancet 390 (10103), 1664-1675, 2017
6632017
An iron-responsive element type II in the 5′-untranslated region of the Alzheimer's amyloid precursor protein transcript
JT Rogers, JD Randall, CM Cahill, PS Eder, X Huang, H Gunshin, L Leiter, ...
Journal of Biological Chemistry 277 (47), 45518-45528, 2002
6532002
GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism
Y Li, TA Perry, MS Kindy, BK Harvey, D Tweedie, HW Holloway, K Powers, ...
Proceedings of the National Academy of Sciences 106 (4), 1285-1290, 2009
6392009
Drug discovery and development: Role of basic biological research
RC Mohs, NH Greig
Alzheimer's & Dementia: Translational Research & Clinical Interventions 3 (4 …, 2017
6132017
A new therapeutic target in Alzheimer's disease treatment: attention to butyrylcholinesterase
NH Greig, T Utsuki, Q Yu, X Zhu, HW Holloway, TA Perry, B Lee, ...
Current medical research and opinion 17 (3), 159-165, 2001
5692001
Butyrylcholinesterase: an important new target in Alzheimer's disease therapy
NH Greig, DK Lahiri, K Sambamurti
International psychogeriatrics 14 (S1), 77-91, 2002
4972002
Running-induced systemic cathepsin B secretion is associated with memory function
HY Moon, A Becke, D Berron, B Becker, N Sah, G Benoni, E Janke, ...
Cell metabolism 24 (2), 332-340, 2016
4912016
Exendin-4 decelerates food intake, weight gain, and fat deposition in Zucker rats
M Szayna, ME Doyle, JA Betkey, HW Holloway, RGS Spencer, NH Greig, ...
Endocrinology 141 (6), 1936-1941, 2000
4372000
Protection and reversal of excitotoxic neuronal damage by glucagon-like peptide-1 and exendin-4
TA Perry, NJ Haughey, MP Mattson, JM Egan, NH Greig
Journal of Pharmacology and Experimental Therapeutics 302 (3), 881-888, 2002
4262002
Cholinesterases: roles in the brain during health and disease
CG Ballard, NH Greig, AL Guillozet-Bongaarts, A Enz, S Darvesh
Current Alzheimer Research 2 (3), 307-318, 2005
4162005
Glucagon‐like peptide‐1 decreases endogenous amyloid‐β peptide (Aβ) levels and protects hippocampal neurons from death induced by Aβ and iron
TA Perry, DK Lahiri, K Sambamurti, D Chen, MP Mattson, JM Egan, ...
Journal of neuroscience research 72 (5), 603-612, 2003
4102003
N-methyl D-aspartate (NMDA) receptor antagonists and memantine treatment for Alzheimer’s disease, vascular dementia and Parkinson’s disease
D Olivares, V K Deshpande, Y Shi, D K Lahiri, N H Greig, J T Rogers, ...
Current Alzheimer Research 9 (6), 746-758, 2012
4082012
A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid β‐peptide
C Culmsee, X Zhu, QS Yu, SL Chan, S Camandola, Z Guo, NH Greig, ...
Journal of neurochemistry 77 (1), 220-228, 2001
3942001
Amyloid-beta protein clearance and degradation (ABCD) pathways and their role in Alzheimer’s disease
R J Baranello, K L Bharani, V Padmaraju, N Chopra, D K Lahiri, N H Greig, ...
Current Alzheimer Research 12 (1), 32-46, 2015
3722015
A novel neurotrophic property of glucagon-like peptide 1: a promoter of nerve growth factor-mediated differentiation in PC12 cells
TA Perry, DK Lahiri, D Chen, JIE Zhou, KTY Shaw, JM Egan, NH Greig
Journal of Pharmacology and Experimental Therapeutics 300 (3), 958-966, 2002
3542002
GLP-1 receptor stimulation reduces amyloid-β peptide accumulation and cytotoxicity in cellular and animal models of Alzheimer's disease
Y Li, KB Duffy, MA Ottinger, B Ray, JA Bailey, HW Holloway, D Tweedie, ...
Journal of Alzheimer's disease 19 (4), 1205-1219, 2010
3522010
TNF-α protein synthesis inhibitor restores neuronal function and reverses cognitive deficits induced by chronic neuroinflammation
K Belarbi, T Jopson, D Tweedie, C Arellano, W Luo, NH Greig, S Rosi
Journal of neuroinflammation 9, 1-13, 2012
3222012
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