Bastian Zimmer
Bastian Zimmer
Group Leader, iPSC R&D, Evotec SE
Verified email at
Cited by
Cited by
Deriving human ENS lineages for cell therapy and drug discovery in Hirschsprung disease
F Fattahi, JA Steinbeck, S Kriks, J Tchieu, B Zimmer, S Kishinevsky, ...
Nature 531 (7592), 105, 2016
Combined small-molecule inhibition accelerates the derivation of functional cortical neurons from human pluripotent stem cells
Y Qi, XJ Zhang, N Renier, Z Wu, T Atkin, Z Sun, MZ Ozair, J Tchieu, ...
Nature biotechnology 35 (2), 154, 2017
A Modular Platform for Differentiation of Human PSCs into All Major Ectodermal Lineages
J Tchieu, B Zimmer, F Fattahi, S Amin, N Zeltner, S Chen, L Studer
Cell Stem Cell 21 (3), 399-410. e7, 2017
Markers of murine embryonic and neural stem cells, neurons and astrocytes: reference points for developmental neurotoxicity testing
P Kügler, B Zimmer, T Waldmann, B Baudis, S Ilmjärv, J Hescheler, ...
Alternatives to animal experimentation: ALTEX 27 (1), 16-42, 2010
Reference compounds for alternative test methods to indicate developmental neurotoxicity (DNT) potential of chemicals: example lists and criteria for their selection and use.
M Aschner, S Ceccatelli, M Daneshian, E Fritsche, N Hasiwa, T Hartung, ...
ALTEX, 2016
Coordinated waves of gene expression during neuronal differentiation of embryonic stem cells as basis for novel approaches to developmental neurotoxicity testing
B Zimmer, PB Kuegler, B Baudis, A Genewsky, V Tanavde, W Koh, B Tan, ...
Cell death and differentiation 18 (3), 383, 2011
Evaluation of developmental toxicants and signaling pathways in a functional test based on the migration of human neural crest cells
B Zimmer, G Lee, NV Balmer, K Meganathan, A Sachinidis, L Studer, ...
Environmental health perspectives 120 (8), 1116, 2012
Epigenetic changes and disturbed neural development in a human embryonic stem cell-based model relating to the fetal valproate syndrome
NV Balmer, MK Weng, B Zimmer, VN Ivanova, SM Chambers, ...
Human Molecular Genetics 21 (18), 4104-4114, 2012
Specification of functional cranial placode derivatives from human pluripotent stem cells
Z Dincer, J Piao, L Niu, Y Ganat, S Kriks, B Zimmer, SH Shi, V Tabar, ...
Cell reports 5 (5), 1387-1402, 2013
Compound selection for in vitro modeling of developmental neurotoxicity
S Kadereit, B Zimmer, C van Thriel, JG Hengstler, M Leist
Front Biosci 17, 2442-2460, 2012
Inborn Errors of RNA Lariat Metabolism in Humans with Brainstem Viral Infection
SY Zhang, NE Clark, CA Freije, E Pauwels, AJ Taggart, S Okada, ...
Cell 172 (5), 952-965. e18, 2018
Sensitivity of dopaminergic neuron differentiation from stem cells to chronic low-dose methylmercury exposure
B Zimmer, S Schildknecht, PB Kuegler, V Tanavde, S Kadereit, M Leist
Toxicological Sciences 121 (2), 357-367, 2011
Profiling of drugs and environmental chemicals for functional impairment of neural crest migration in a novel stem cell-based test battery
B Zimmer, G Pallocca, N Dreser, S Foerster, T Waldmann, J Westerhout, ...
Archives of toxicology 88 (5), 1109-1126, 2014
Human SNORA31 variations impair cortical neuron-intrinsic immunity to HSV-1 and underlie herpes simplex encephalitis
FG Lafaille, O Harschnitz, YS Lee, P Zhang, ML Hasek, G Kerner, Y Itan, ...
Nature Medicine 25 (12), 1873-1884, 2019
Lipid Deprivation Induces a Stable, Naive-to-Primed Intermediate State of Pluripotency in Human PSCs
D Cornacchia, C Zhang, B Zimmer, SY Chung, Y Fan, MA Soliman, ...
Cell stem cell, 2019
Human iPSC-derived trigeminal neurons lack constitutive TLR3-dependent immunity that protects cortical neurons from HSV-1 infection
B Zimmer, O Ewaleifoh, O Harschnitz, YS Lee, C Peneau, JL McAlpine, ...
Proceedings of the National Academy of Sciences 115 (37), E8775-E8782, 2018
Capturing the biology of disease severity in a PSC-based model of familial dysautonomia
N Zeltner, F Fattahi, NC Dubois, N Saurat, F Lafaille, L Shang, B Zimmer, ...
Nature medicine 22 (12), 1421, 2016
Derivation of Diverse Hormone-Releasing Pituitary Cells from Human Pluripotent Stem Cells
B Zimmer, J Piao, K Ramnarine, MJ Tomishima, V Tabar, L Studer
Stem Cell Reports 6 (6), 858-872, 2016
GFAP‐independent inflammatory competence and trophic functions of astrocytes generated from murine embryonic stem cells
PB Kuegler, BA Baumann, B Zimmer, S Keller, A Marx, S Kadereit, M Leist
Glia 60 (2), 218-228, 2012
Acrylamide alters neurotransmitter induced calcium responses in murine ESC-derived and primary neurons
J Sisnaiske, V Hausherr, AK Krug, B Zimmer, JG Hengstler, M Leist, ...
Neurotoxicology 43, 117-126, 2014
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