The tumor immune microenvironment drives a prognostic relevance that correlates with bladder cancer subtypes C Pfannstiel, PL Strissel, KB Chiappinelli, D Sikic, S Wach, RM Wirtz, ... Cancer immunology research 7 (6), 923-938, 2019 | 155 | 2019 |
Deep learning predicts molecular subtype of muscle-invasive bladder cancer from conventional histopathological slides AC Woerl, M Eckstein, J Geiger, DC Wagner, T Daher, P Stenzel, ... European urology 78 (2), 256-264, 2020 | 149 | 2020 |
Results from BLASST-1 (Bladder Cancer Signal Seeking Trial) of nivolumab, gemcitabine, and cisplatin in muscle invasive bladder cancer (MIBC) undergoing cystectomy. S Gupta, G Sonpavde, CJ Weight, BA McGregor, S Gupta, BL Maughan, ... Journal of Clinical Oncology 38 (6_suppl), 439-439, 2020 | 137 | 2020 |
Multistain deep learning for prediction of prognosis and therapy response in colorectal cancer S Foersch, C Glasner, AC Woerl, M Eckstein, DC Wagner, S Schulz, ... Nature medicine 29 (2), 430-439, 2023 | 125 | 2023 |
PD-L1 assessment in urothelial carcinoma: a practical approach M Eckstein, A Cimadamore, A Hartmann, A Lopez-Beltran, L Cheng, ... Annals of Translational Medicine 7 (22), 2019 | 109 | 2019 |
Performance of the Food and Drug Administration/EMA-approved programmed cell death ligand-1 assays in urothelial carcinoma with emphasis on therapy stratification for first … M Eckstein, P Erben, MC Kriegmair, TS Worst, CA Weiß, RM Wirtz, ... European journal of cancer 106, 234-243, 2019 | 102 | 2019 |
Deep learning for diagnosis and survival prediction in soft tissue sarcoma S Foersch, M Eckstein, DC Wagner, F Gach, AC Woerl, J Geiger, ... Annals of Oncology 32 (9), 1178-1187, 2021 | 91 | 2021 |
Membranous NECTIN-4 expression frequently decreases during metastatic spread of urothelial carcinoma and is associated with enfortumab vedotin resistance N Klümper, DJ Ralser, J Ellinger, F Roghmann, J Albrecht, E Below, ... Clinical Cancer Research 29 (8), 1496-1505, 2023 | 89 | 2023 |
EMT transcription factor ZEB1 alters the epigenetic landscape of colorectal cancer cells P Lindner, S Paul, M Eckstein, C Hampel, JK Muenzner, ... Cell death & disease 11 (2), 147, 2020 | 86 | 2020 |
FGFR3 mutation status and FGFR3 expression in a large bladder cancer cohort treated by radical cystectomy: implications for anti-FGFR3 treatment? BWG van Rhijn, LS Mertens, R Mayr, PJ Bostrom, FX Real, EC Zwarthoff, ... European Urology 78 (5), 682-687, 2020 | 79 | 2020 |
Safety and efficacy of single cycle induction treatment with cisplatin/docetaxel/durvalumab/tremelimumab in locally advanced HNSCC: first results of CheckRad-CD8 M Hecht, AO Gostian, M Eckstein, S Rutzner, J von der Grün, T Illmer, ... Journal for immunotherapy of cancer 8 (2), 2020 | 71 | 2020 |
In stage pT1 non-muscle-invasive bladder cancer (NMIBC), high KRT20 and low KRT5 mRNA expression identify the luminal subtype and predict recurrence and survival J Breyer, RM Wirtz, W Otto, P Erben, MC Kriegmair, R Stoehr, M Eckstein, ... Virchows Archiv 470, 267-274, 2017 | 71 | 2017 |
High PDL1 mRNA expression predicts better survival of stage pT1 non-muscle-invasive bladder cancer (NMIBC) patients J Breyer, RM Wirtz, W Otto, P Erben, TS Worst, R Stoehr, M Eckstein, ... Cancer Immunology, Immunotherapy 67, 403-412, 2018 | 69 | 2018 |
Collective forces of tumor spheroids in three-dimensional biopolymer networks C Mark, TJ Grundy, PL Strissel, D Böhringer, N Grummel, R Gerum, ... Elife 9, e51912, 2020 | 68 | 2020 |
MiR-205-driven downregulation of cholesterol biosynthesis through SQLE-inhibition identifies therapeutic vulnerability in aggressive prostate cancer C Kalogirou, J Linxweiler, P Schmucker, MT Snaebjornsson, W Schmitz, ... Nature communications 12 (1), 5066, 2021 | 58 | 2021 |
DAPK1 loss triggers tumor invasion in colorectal tumor cells S Steinmann, P Kunze, C Hampel, M Eckstein, J Bertram Bramsen, ... Cell death & disease 10 (12), 895, 2019 | 55 | 2019 |
Cytotoxic T-cell-related gene expression signature predicts improved survival in muscle-invasive urothelial bladder cancer patients after radical cystectomy and adjuvant … M Eckstein, P Strissel, R Strick, V Weyerer, R Wirtz, C Pfannstiel, ... Journal for Immunotherapy of Cancer 8 (1), 2020 | 53 | 2020 |
mRNA-Expression of KRT5 and KRT20 Defines Distinct Prognostic Subgroups of Muscle-Invasive Urothelial Bladder Cancer Correlating with Histological Variants M Eckstein, RM Wirtz, M Gross-Weege, J Breyer, W Otto, R Stoehr, D Sikic, ... International journal of molecular sciences 19 (11), 3396, 2018 | 52 | 2018 |
Prospective development and validation of a liquid immune profile-based signature (LIPS) to predict response of patients with recurrent/metastatic cancer to immune checkpoint … JG Zhou, AJ Donaubauer, B Frey, I Becker, S Rutzner, M Eckstein, R Sun, ... Journal for Immunotherapy of Cancer 9 (2), 2021 | 45 | 2021 |
CDKN2A as transcriptomic marker for muscle-invasive bladder cancer risk stratification and therapy decision-making TS Worst, CA Weis, R Stöhr, S Bertz, M Eckstein, W Otto, J Breyer, ... Scientific reports 8 (1), 14383, 2018 | 44 | 2018 |