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Akos Nyerges
Akos Nyerges
Laboratory of George M Church | Harvard Medical School | Email: akos_nyerges [at] hms.harvard.edu
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Jahr
Antibiotic-resistant bacteria show widespread collateral sensitivity to antimicrobial peptides
V Lázár, A Martins, R Spohn, L Daruka, G Grézal, G Fekete, M Számel, ...
Nature microbiology 3 (6), 718-731, 2018
3182018
Genome-wide analysis captures the determinants of the antibiotic cross-resistance interaction network
V Lázár, I Nagy, R Spohn, B Csörgő, Á Györkei, Á Nyerges, B Horváth, ...
Nature communications 5 (1), 4352, 2014
2252014
A highly precise and portable genome engineering method allows comparison of mutational effects across bacterial species
Á Nyerges, B Csörgő, I Nagy, B Bálint, P Bihari, V Lázár, G Apjok, ...
Proceedings of the National Academy of Sciences 113 (9), 2502-2507, 2016
2042016
Phenotypic heterogeneity promotes adaptive evolution
Z Bódi, Z Farkas, D Nevozhay, D Kalapis, V Lázár, B Csörgő, Á Nyerges, ...
PLoS biology 15 (5), e2000644, 2017
1562017
Improved bacterial recombineering by parallelized protein discovery
TM Wannier, A Nyerges, HM Kuchwara, M Czikkely, D Balogh, ...
Proceedings of the National Academy of Sciences 117 (24), 13689-13698, 2020
1032020
Directed evolution of multiple genomic loci allows the prediction of antibiotic resistance
Á Nyerges, B Csörgő, G Draskovits, B Kintses, P Szili, G Ferenc, T Révész, ...
Proceedings of the National Academy of Sciences 115 (25), E5726-E5735, 2018
902018
Phylogenetic barriers to horizontal transfer of antimicrobial peptide resistance genes in the human gut microbiota
B Kintses, O Méhi, E Ari, M Számel, Á Györkei, PK Jangir, I Nagy, F Pál, ...
Nature microbiology 4 (3), 447-458, 2019
772019
Perturbation of iron homeostasis promotes the evolution of antibiotic resistance
O Méhi, B Bogos, B Csörgő, F Pál, Á Nyerges, B Papp, C Pál
Molecular biology and evolution 31 (10), 2793-2804, 2014
652014
Recombineering and MAGE
TM Wannier, PN Ciaccia, AD Ellington, GT Filsinger, FJ Isaacs, ...
Nature Reviews Methods Primers 1 (1), 7, 2021
612021
Enzyme promiscuity shapes adaptation to novel growth substrates
GI Guzmán, TE Sandberg, RA LaCroix, Á Nyerges, H Papp, M de Raad, ...
Molecular systems biology 15 (4), e8462, 2019
612019
Conditional DNA repair mutants enable highly precise genome engineering
A Nyerges, B Csörgő, I Nagy, D Latinovics, B Szamecz, G Pósfai, C Pal
Nucleic Acids Research 42 (8), e62-e62, 2014
582014
Genome-wide abolishment of mobile genetic elements using genome shuffling and CRISPR/Cas-assisted MAGE allows the efficient stabilization of a bacterial chassis
K Umenhoffer, G Draskovits, A Nyerges, I Karcagi, B Bogos, E Tímár, ...
ACS Synthetic Biology 6 (8), 1471-1483, 2017
572017
New N-phenylpyrrolamide DNA gyrase B inhibitors: Optimization of efficacy and antibacterial activity
M Durcik, D Lovison, Ž Skok, CD Cruz, P Tammela, T Tomašič, DB Tiz, ...
European journal of medicinal chemistry 154, 117-132, 2018
472018
An optimised series of substituted N-phenylpyrrolamides as DNA gyrase B inhibitors
DB Tiz, Ž Skok, M Durcik, T Tomašič, LP Mašič, J Ilaš, A Zega, ...
European journal of medicinal chemistry 167, 269-290, 2019
402019
Limited evolutionary conservation of the phenotypic effects of antibiotic resistance mutations
G Apjok, G Boross, Á Nyerges, G Fekete, V Lázár, B Papp, C Pál, ...
Molecular biology and evolution 36 (8), 1601-1611, 2019
392019
A standardized workflow for surveying recombinases expands bacterial genome‐editing capabilities
DE Ricaurte, E Martínez‐García, A Nyerges, C Pal, V de Lorenzo, ...
Microbial Biotechnology 11 (1), 176-188, 2018
392018
High-efficiency multi-site genomic editing of Pseudomonas putida through thermoinducible ssDNA recombineering
T Aparicio, A Nyerges, E Martínez-García, V de Lorenzo
Iscience 23 (3), 2020
352020
System-level genome editing in microbes
B Csörgő, Á Nyerges, G Pósfai, T Fehér
Current Opinion in Microbiology 33, 113-122, 2016
312016
Rapid evolution of reduced susceptibility against a balanced dual-targeting antibiotic through stepping-stone mutations
P Szili, G Draskovits, T Révész, F Bogár, D Balogh, T Martinek, L Daruka, ...
Antimicrobial agents and chemotherapy 63 (9), 10.1128/aac. 00207-19, 2019
302019
A swapped genetic code prevents viral infections and gene transfer
A Nyerges, S Vinke, R Flynn, SV Owen, EA Rand, B Budnik, E Keen, ...
Nature 615 (7953), 720-727, 2023
232023
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