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Paula Römer
Paula Römer
Senior Scientist, Catalym GmbH
Verified email at catalym.com
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Year
Preculture of PBMCs at high cell density increases sensitivity of T-cell responses, revealing cytokine release by CD28 superagonist TGN1412
PS Römer, S Berr, E Avota, SY Na, M Battaglia, I ten Berge, H Einsele, ...
Blood, The Journal of the American Society of Hematology 118 (26), 6772-6782, 2011
1982011
Human regulatory T cells are selectively activated by low‐dose application of the CD28 superagonist TGN1412/TAB08
P Tabares, S Berr, PS Römer, S Chuvpilo, AA Matskevich, D Tyrsin, ...
European journal of immunology 44 (4), 1225-1236, 2014
1202014
Cell contact–dependent priming and Fc interaction with CD32+ immune cells contribute to the TGN1412-triggered cytokine response
P Bartholomaeus, LY Semmler, T Bukur, V Boisguerin, PS Roemer, ...
The Journal of Immunology 192 (5), 2091-2098, 2014
642014
From TGN1412 to TAB08: the return of CD28 superagonist therapy to clinical development for the treatment of rheumatoid arthritis
D Tyrsin, S Chuvpilo, A Matskevich, D Nemenov, PS Römer, P Tabares, ...
Clinical and experimental rheumatology 34 (4 Suppl 98), 45-48, 2016
502016
Antibody dose and corticosteroid sensitivity separate TGN1412 induced inflammatory cytokine release from activation of regulatory T-cells
PTWS Berr, PS Römer, SCWA Matckevich, DTWY Fedotov, HEWHP Tony, ...
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