Multiple ligand-specific conformations of the β2-adrenergic receptor AW Kahsai, K Xiao, S Rajagopal, S Ahn, AK Shukla, J Sun, TG Oas, ... Nature chemical biology 7 (10), 692-700, 2011 | 290 | 2011 |
Global phosphorylation analysis of β-arrestin–mediated signaling downstream of a seven transmembrane receptor (7TMR) K Xiao, J Sun, J Kim, S Rajagopal, B Zhai, J Villén, W Haas, JJ Kovacs, ... Proceedings of the National Academy of Sciences 107 (34), 15299-15304, 2010 | 225 | 2010 |
PRL3 promotes cell invasion and proliferation by down-regulation of Csk leading to Src activation F Liang, J Liang, WQ Wang, JP Sun, E Udho, ZY Zhang Journal of Biological Chemistry 282 (8), 5413-5419, 2007 | 211 | 2007 |
Crystal structure of PTP1B complexed with a potent and selective bidentate inhibitor JP Sun, AA Fedorov, SY Lee, XL Guo, K Shen, DS Lawrence, SC Almo, ... Journal of Biological Chemistry 278 (14), 12406-12414, 2003 | 183 | 2003 |
Structure, inhibitor, and regulatory mechanism of Lyp, a lymphoid-specific tyrosine phosphatase implicated in autoimmune diseases X Yu, JP Sun, Y He, X Guo, S Liu, B Zhou, A Hudmon, ZY Zhang Proceedings of the National Academy of Sciences 104 (50), 19767-19772, 2007 | 163 | 2007 |
Structural basis of docking interactions between ERK2 and MAP kinase phosphatase 3 S Liu, JP Sun, B Zhou, ZY Zhang Proceedings of the National Academy of Sciences 103 (14), 5326-5331, 2006 | 153 | 2006 |
An overview of the protein tyrosine phosphatase superfamily WQ Wang, JP Sun, ZY Zhang Current topics in medicinal chemistry 3 (7), 739-748, 2003 | 134 | 2003 |
Divergent transducer-specific molecular efficacies generate biased agonism at a G protein-coupled receptor (GPCR) RT Strachan, J Sun, DH Rominger, JD Violin, S Ahn, ARB Thomsen, ... Journal of Biological Chemistry 289 (20), 14211-14224, 2014 | 126 | 2014 |
Structure and biochemical properties of PRL-1, a phosphatase implicated in cell growth, differentiation, and tumor invasion JP Sun, WQ Wang, H Yang, S Liu, F Liang, AA Fedorov, SC Almo, ... Biochemistry 44 (36), 12009-12021, 2005 | 122 | 2005 |
Phosphatase activity, trimerization, and the C-terminal polybasic region are all required for PRL1-mediated cell growth and migration JP Sun, Y Luo, X Yu, WQ Wang, B Zhou, F Liang, ZY Zhang Journal of Biological Chemistry 282 (39), 29043-29051, 2007 | 107 | 2007 |
The catalytic region and PEST domain of PTPN18 distinctly regulate the HER2 phosphorylation and ubiquitination barcodes HM Wang, YF Xu, SL Ning, DX Yang, Y Li, YJ Du, F Yang, Y Zhang, ... Cell Research, 2014 | 80 | 2014 |
Beta2-adrenergic receptor and astrocyte glucose metabolism J Dong, X Chen, M Cui, X Yu, Q Pang, J Sun Journal of Molecular Neuroscience 48 (2), 456-463, 2012 | 76 | 2012 |
Constitutive Gαi Coupling Activity of VLGR1 and its Regulation by PDZD7 QX Hu, JH Dong, HB Du, DL Zhang, HZ Ren, ML Ma, Y Cai, TC Zhao, ... Journal of Biological Chemistry, jbc. M114. 549816, 2014 | 72 | 2014 |
Crystal structure of the Yersinia protein-tyrosine phosphatase YopH complexed with a specific small molecule inhibitor JP Sun, L Wu, AA Fedorov, SC Almo, ZY Zhang Journal of Biological Chemistry 278 (35), 33392-33399, 2003 | 72 | 2003 |
Cadmium is a potent inhibitor of PPM phosphatases and targets the M1 binding site C Pan, HD Liu, Z Gong, X Yu, XB Hou, DD Xie, XB Zhu, HW Li, JY Tang, ... Scientific reports 3, 2013 | 64 | 2013 |
Monitoring protein conformational changes and dynamics using stable-isotope labeling and mass spectrometry AW Kahsai, S Rajagopal, J Sun, K Xiao Nature protocols 9 (6), 1301-1319, 2014 | 61 | 2014 |
A genetically encoded 19F NMR probe for tyrosine phosphorylation F Li, P Shi, J Li, F Yang, T Wang, W Zhang, F Gao, W Ding, D Li, J Li, ... Angewandte Chemie 125 (14), 4050-4054, 2013 | 48 | 2013 |
Targeted Disruption of β-Arrestin 2-Mediated Signaling Pathways by Aptamer Chimeras Leads to Inhibition of Leukemic Cell Growth JW Kotula, J Sun, M Li, ED Pratico, MP Fereshteh, DP Ahrens, ... PloS one 9 (4), e93441, 2014 | 47 | 2014 |
Marchantin M: a novel inhibitor of proteasome induces autophagic cell death in prostate cancer cells H Jiang, J Sun, Q Xu, Y Liu, J Wei, CYF Young, H Yuan, H Lou Cell death & disease 4 (8), e761, 2013 | 46 | 2013 |
A stress response pathway in mice upregulates somatostatin level and transcription in pancreatic delta cells through Gs and β-arrestin 1 HM Wang, JH Dong, Q Li, Q Hu, SL Ning, W Zheng, M Cui, TS Chen, ... Diabetologia, 1-12, 2014 | 45 | 2014 |