Ubiquitin modulates liquid-liquid phase separation of UBQLN2 via disruption of multivalent interactions TP Dao, RM Kolaitis, HJ Kim, K O’Donovan, B Martyniak, E Colicino, ... Molecular cell 69 (6), 965-978. e6, 2018 | 291 | 2018 |
β-Barrel proteins that reside in the Escherichia coli outer membrane in vivo demonstrate varied folding behavior in vitro NK Burgess, TP Dao, AM Stanley, KG Fleming Journal of Biological Chemistry 283 (39), 26748-26758, 2008 | 272 | 2008 |
ALS-linked mutations affect UBQLN2 oligomerization and phase separation in a position-and amino acid-dependent manner TP Dao, B Martyniak, AJ Canning, Y Lei, EG Colicino, MS Cosgrove, ... Structure 27 (6), 937-951. e5, 2019 | 84 | 2019 |
Single amino acid substitutions in stickers, but not spacers, substantially alter UBQLN2 phase transitions and dense phase material properties Y Yang, HB Jones, TP Dao, CA Castañeda The Journal of Physical Chemistry B 123 (17), 3618-3629, 2019 | 62 | 2019 |
High-resolution mapping of a repeat protein folding free energy landscape MJ Fossat, TP Dao, K Jenkins, M Dellarole, Y Yang, SA McCallum, ... Biophysical Journal 111 (11), 2368-2376, 2016 | 37 | 2016 |
Ubiquitin‐modulated phase separation of shuttle proteins: Does condensate formation promote protein degradation? TP Dao, CA Castañeda Bioessays 42 (11), 2000036, 2020 | 30 | 2020 |
Mechanistic insights into enhancement or inhibition of phase separation by different polyubiquitin chains TP Dao, Y Yang, MF Presti, MS Cosgrove, JB Hopkins, W Ma, SN Loh, ... EMBO reports 23 (8), e55056, 2022 | 29 | 2022 |
Capping motifs stabilize the leucine‐rich repeat protein PP32 and rigidify adjacent repeats TP Dao, A Majumdar, D Barrick Protein Science 23 (6), 801-811, 2014 | 26 | 2014 |
Highly polarized C-terminal transition state of the leucine-rich repeat domain of PP32 is governed by local stability TP Dao, A Majumdar, D Barrick Proceedings of the National Academy of Sciences 112 (18), E2298-E2306, 2015 | 21 | 2015 |
PIRL1 and PIRL9, encoding members of a novel plant-specific family of leucine-rich repeat proteins, are essential for differentiation of microspores into pollen NR Forsthoefel, TP Dao, DM Vernon Planta 232, 1101-1114, 2010 | 18 | 2010 |
Ion Mobility mass spectrometry unveils global protein conformations in response to conditions that promote and reverse liquid–liquid phase separation CG Robb, TP Dao, J Ujma, CA Castañeda, R Beveridge Journal of the American Chemical Society 145 (23), 12541-12549, 2023 | 7 | 2023 |
Polyubiquitin ligand-induced phase transitions are optimized by spacing between ubiquitin units SKK Galagedera, TP Dao, SE Enos, A Chaudhuri, JD Schmit, ... Proceedings of the National Academy of Sciences 120 (42), e2306638120, 2023 | 3 | 2023 |
Short disordered termini and proline-rich domain are major regulators of UBQLN1/2/4 phase separation TP Dao, A Rajendran, SKK Galagedera, W Haws, CA Castañeda Biophysical Journal, 2023 | 2 | 2023 |
Decoding optimal ligand design for multicomponent condensates SKK Galagedera, TP Dao, SE Enos, A Chaudhuri, JD Schmit, ... bioRxiv, 2023 | 2 | 2023 |
Pathogenic mutations in UBQLN2 exhibit diverse aggregation propensity and neurotoxicity N Safren, TP Dao, HM Mohan, C Huang, B Trotter, CA Castañeda, ... Scientific reports 14 (1), 6049, 2024 | 1 | 2024 |
Cancer Mutations in SPOP Put a Stop to Its Inter-compartmental Hops JF Riley, TP Dao, CA Castañeda Molecular cell 72 (1), 1-3, 2018 | 1 | 2018 |
Phase separation of polyubiquitinated proteins in UBQLN2 condensates controls substrate fate IM Valentino, JG Llivicota-Guaman, TP Dao, EO Mulvey, AM Lehman, ... bioRxiv, 2024.03. 15.585243, 2024 | | 2024 |
We con-dense if we want to; We can’t leave AZUL outside TP Dao, CA Castañeda Structure 31 (4), 369-371, 2023 | | 2023 |