Lars V. Bock
Lars V. Bock
Project Leader, Theoretical and Computational Biophysics, MPI for Multidisciplinary Sciences
Verified email at - Homepage
Cited by
Cited by
Structure of the E. coli ribosome–EF-Tu complex at< 3 Ċ resolution by Cs-corrected cryo-EM.
N Fischer, P Neumann, AL Konevega, LV Bock, R Ficner, MV Rodnina, ...
Nature 520 (7548), 567-570, 2015
Energy barriers and driving forces in tRNA translocation through the ribosome
LV Bock, C Blau, GF Schröder, II Davydov, N Fischer, H Stark, ...
Nature structural & molecular biology 20 (12), 1390-1396, 2013
Structural Basis for Polyproline-Mediated Ribosome Stalling and Rescue by the Translation Elongation Factor EF-P
P Huter, S Arenz, LV Bock, M Graf, JO Frister, A Heuer, L Peil, AL Starosta, ...
Molecular Cell 68 (3), 515-527. e6, 2017
The pathway to GTPase activation of elongation factor SelB on the ribosome
N Fischer, P Neumann, LV Bock, C Maracci, Z Wang, A Paleskava, ...
Nature 540 (7631), 80-85, 2016
A combined cryo-EM and molecular dynamics approach reveals the mechanism of ErmBL-mediated translation arrest
S Arenz, LV Bock, M Graf, CA Innis, R Beckmann, H Grubmüller, ...
Nature communications 7 (1), 12026, 2016
Automated cryo-EM structure refinement using correlation-driven molecular dynamics
M Igaev, C Kutzner, LV Bock, AC Vaiana, H Grubmüller
eLife 8, e43542, 2019
Structural and mechanistic basis for translation inhibition by macrolide and ketolide antibiotics
B Beckert, EC Leroy, S Sothiselvam, LV Bock, MS Svetlov, M Graf, ...
Nature Communications 12 (1), 4466, 2021
Active role of elongation factor G in maintaining the mRNA reading frame during translation
BZ Peng, LV Bock, R Belardinelli, F Peske, H Grubmüller, MV Rodnina
Science Advances 5 (12), eaax8030, 2019
Thermodynamic Control of –1 Programmed Ribosomal Frameshifting
LV Bock, N Caliskan, N Korniy, F Peske, MV Rodnina, H Grubmüller
Nature Communications 10, 2019
Molecular simulations of the ribosome and associated translation factors
LV Bock, MH Kolář, H Grubmüller
Current Opinion in Structural Biology 49, 27-35, 2018
Effects of cryo-EM cooling on structural ensembles
LV Bock, H Grubmüller
Nature Communications 13, 1709, 2022
Dynamic contact network between ribosomal subunits enables rapid large-scale rotation during spontaneous translocation
LV Bock, C Blau, AC Vaiana, H Grubmüller
Nucleic acids research 43 (14), 6747-6760, 2015
Chemomechanical regulation of SNARE proteins studied with molecular dynamics simulations
LV Bock, B Hutchings, H Grubmüller, DJ Woodbury
Biophysical journal 99 (4), 1221-1230, 2010
tRNA dissociation from EF-Tu after GTP hydrolysis: primary steps and antibiotic inhibition
M Warias, H Grubmüller, LV Bock
Biophysical journal 118 (1), 151-161, 2020
Structural conservation of antibiotic interaction with ribosomes
H Paternoga, C Crowe-McAuliffe, LV Bock, TO Koller, M Morici, B Beckert, ...
Nature Structural & Molecular Biology 30 (9), 1380-1392, 2023
Folding of VemP into translation-arresting secondary structure is driven by the ribosome exit tunnel
MH Kolář, G Nagy, J Kunkel, SM Vaiana, LV Bock, H Grubmüller
Nucleic Acids Research 50 (4), 2258-2269, 2022
Simulation of Complex Biomolecular Systems: The Ribosome Challenge
LV Bock, S Gabrielli, MH Kolář, H Grubmüller
Annual Review of Biophysics 52, 2023
The SecM arrest peptide traps a pre-peptide bond formation state of the ribosome
F Gersteuer, M Morici, S Gabrielli, K Fujiwara, HA Safdari, H Paternoga, ...
Nature Communications 15 (1), 2431, 2024
RAPP-containing arrest peptides induce translational stalling by short circuiting the ribosomal peptidyltransferase activity
M Morici, S Gabrielli, K Fujiwara, H Paternoga, B Beckert, LV Bock, ...
Nature Communications 15 (1), 2432, 2024
tRNA dissociation from EF-Tu after GTP hydrolysis and Pi release: primary steps and antibiotic inhibition
M Warias, H Grubmüller, LV Bock
BioRxiv, 602383, 2019
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