Martin Reijns
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cGAS surveillance of micronuclei links genome instability to innate immunity
KJ Mackenzie, P Carroll, CA Martin, O Murina, A Fluteau, DJ Simpson, ...
Nature 548 (7668), 461-465, 2017
Enzymatic removal of ribonucleotides from DNA is essential for mammalian genome integrity and development
MAM Reijns, B Rabe, RE Rigby, P Mill, KR Astell, LA Lettice, S Boyle, ...
Cell 149 (5), 1008-1022, 2012
A role for Q/N-rich aggregation-prone regions in P-body localization
MAM Reijns, RD Alexander, MP Spiller, JD Beggs
Journal of cell science 121 (15), 2463-2472, 2008
Lagging-strand replication shapes the mutational landscape of the genome
MAM Reijns, H Kemp, J Ding, SM de Procé, AP Jackson, MS Taylor
Nature 518 (7540), 502-506, 2015
Ribonucleotides misincorporated into DNA act as strand-discrimination signals in eukaryotic mismatch repair
MM Ghodgaonkar, F Lazzaro, M Olivera-Pimentel, M Artola-Borán, ...
Molecular cell 50 (3), 323-332, 2013
Identification of VP19 and VP15 of white spot syndrome virus (WSSV) and glycosylation status of the WSSV major structural proteins
MCW van Hulten, M Reijns, AMG Vermeesch, F Zandbergen, JM Vlak
Journal of general virology 83 (1), 257-265, 2002
CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions
M Zimmermann, O Murina, MAM Reijns, A Agathanggelou, R Challis, ...
Nature 559 (7713), 285-289, 2018
Defective removal of ribonucleotides from DNA promotes systemic autoimmunity
C Günther, B Kind, MAM Reijns, N Berndt, M Martinez-Bueno, C Wolf, ...
The Journal of clinical investigation 125 (1), 413-424, 2015
Ribonuclease H2 mutations induce a cGAS/STING‐dependent innate immune response
KJ Mackenzie, P Carroll, L Lettice, Ž Tarnauskaitė, K Reddy, F Dix, ...
The EMBO journal 35 (8), 831-844, 2016
RNA: DNA hybrids are a novel molecular pattern sensed by TLR9
RE Rigby, LM Webb, KJ Mackenzie, Y Li, A Leitch, MAM Reijns, ...
The EMBO journal 33 (6), 542-558, 2014
Human and mouse mutations in WDR35 cause short-rib polydactyly syndromes due to abnormal ciliogenesis
P Mill, PJ Lockhart, E Fitzpatrick, HS Mountford, EA Hall, MAM Reijns, ...
The American Journal of Human Genetics 88 (4), 508-515, 2011
PCNA directs type 2 RNase H activity on DNA replication and repair substrates
D Bubeck, MAM Reijns, SC Graham, KR Astell, EY Jones, AP Jackson
Nucleic acids research 39 (9), 3652-3666, 2011
The structure of the human RNase H2 complex defines key interaction interfaces relevant to enzyme function and human disease
MAM Reijns, D Bubeck, LCD Gibson, SC Graham, GS Baillie, EY Jones, ...
Journal of Biological Chemistry 286 (12), 10530-10539, 2011
TRAIP promotes DNA damage response during genome replication and is mutated in primordial dwarfism
ME Harley, O Murina, A Leitch, MR Higgs, LS Bicknell, G Yigit, ...
Nature genetics 48 (1), 36-43, 2016
Gain-of-function DNMT3A mutations cause microcephalic dwarfism and hypermethylation of Polycomb-regulated regions
P Heyn, CV Logan, A Fluteau, RC Challis, T Auchynnikava, CA Martin, ...
Nature genetics 51 (1), 96-105, 2019
Mutations in DONSON disrupt replication fork stability and cause microcephalic dwarfism
JJ Reynolds, LS Bicknell, P Carroll, MR Higgs, R Shaheen, JE Murray, ...
Nature Genetics 49 (4), 537-549, 2017
Mutagenesis of PepA suggests a new model for the Xer/cer synaptic complex
M Reijns, Y Lu, S Leach, SD Colloms
Molecular microbiology 57 (4), 927-941, 2005
The Lsm2-8 complex determines nuclear localization of the spliceosomal U6 snRNA
MP Spiller, KL Boon, MAM Reijns, JD Beggs
Nucleic acids research 35 (3), 923-929, 2007
Ribonuclease H2 in health and disease.
MA Reijns, AP Jackson
Biochemical Society transactions 42 (4), 717-725, 2014
RNase H2, mutated in Aicardi‐Goutičres syndrome, promotes LINE‐1 retrotransposition
M Benitez‐Guijarro, C Lopez‐Ruiz, Ž Tarnauskaitė, O Murina, ...
The EMBO journal 37 (15), e98506, 2018
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