| Transplantation of mesenchymal stem cells embedded in Atelocollagen® gel to the intervertebral disc: a potential therapeutic model for disc degeneration D Sakai, J Mochida, Y Yamamoto, T Nomura, M Okuma, K Nishimura, ... Biomaterials 24 (20), 3531-3541, 2003 | 623 | 2003 |
| Regenerative effects of transplanting mesenchymal stem cells embedded in atelocollagen to the degenerated intervertebral disc D Sakai, J Mochida, T Iwashina, A Hiyama, H Omi, M Imai, T Nakai, ... Biomaterials 27 (3), 335-345, 2006 | 503 | 2006 |
| Differentiation of mesenchymal stem cells transplanted to a rabbit degenerative disc model: potential and limitations for stem cell therapy in disc regeneration D Sakai, J Mochida, T Iwashina, T Watanabe, T Nakai, K Ando, T Hotta Spine 30 (21), 2379-2387, 2005 | 501 | 2005 |
| Prevention of the neurocristopathy Treacher Collins syndrome through inhibition of p53 function NC Jones, ML Lynn, K Gaudenz, D Sakai, K Aoto, JP Rey, EF Glynn, ... Nature medicine 14 (2), 125-133, 2008 | 472 | 2008 |
| Stem cell therapy for intervertebral disc regeneration: obstacles and solutions D Sakai, GBJ Andersson Nature Reviews Rheumatology 11 (4), 243-256, 2015 | 451 | 2015 |
| Exhaustion of nucleus pulposus progenitor cells with ageing and degeneration of the intervertebral disc D Sakai, Y Nakamura, T Nakai, T Mishima, S Kato, S Grad, M Alini, ... Nature communications 3 (1), 1264, 2012 | 449 | 2012 |
| Easi-CRISPR: a robust method for one-step generation of mice carrying conditional and insertion alleles using long ssDNA donors and CRISPR ribonucleoproteins RM Quadros, H Miura, DW Harms, H Akatsuka, T Sato, T Aida, R Redder, ... Genome biology 18, 1-15, 2017 | 443 | 2017 |
| Transplantation of mesenchymal stem cells in a canine disc degeneration model A Hiyama, J Mochida, T Iwashina, H Omi, T Watanabe, K Serigano, ... Journal of orthopaedic research 26 (5), 589-600, 2008 | 343 | 2008 |
| Defining the phenotype of young healthy nucleus pulposus cells: recommendations of the Spine Research Interest Group at the 2014 annual ORS meeting MV Risbud, ZR Schoepflin, F Mwale, RA Kandel, S Grad, JC Iatridis, ... Journal of Orthopaedic Research 33 (3), 283-293, 2015 | 288 | 2015 |
| Advancing the cellular and molecular therapy for intervertebral disc disease D Sakai, S Grad Advanced drug delivery reviews 84, 159-171, 2015 | 282 | 2015 |
| A phenotypic comparison of intervertebral disc and articular cartilage cells in the rat CR Lee, D Sakai, T Nakai, K Toyama, J Mochida, M Alini, S Grad European Spine Journal 16, 2174-2185, 2007 | 261 | 2007 |
| Challenges and strategies in the repair of ruptured annulus fibrosus CC Guterl, EY See, SBG Blanquer, A Pandit, SJ Ferguson, LM Benneker, ... European cells & materials 25, 1, 2013 | 250 | 2013 |
| Upregulation of the viability of nucleus pulposus cells by bone marrow-derived stromal cells: significance of direct cell-to-cell contact in coculture system Y Yamamoto, J Mochida, D Sakai, T Nakai, K Nishimura, H Kawada, ... Spine 29 (14), 1508-1514, 2004 | 242 | 2004 |
| Cooperative action of Sox9, Snail2 and PKA signaling in early neural crest development D Sakai, T Suzuki, N Osumi, Y Wakamatsu Oxford University Press for The Company of Biologists Limited 133 (7), 1323-1333, 2006 | 229 | 2006 |
| Effect of cell number on mesenchymal stem cell transplantation in a canine disc degeneration model K Serigano, D Sakai, A Hiyama, F Tamura, M Tanaka, J Mochida Journal of orthopaedic research 28 (10), 1267-1275, 2010 | 213 | 2010 |
| Future perspectives of cell-based therapy for intervertebral disc disease D Sakai European spine journal 17 (Suppl 4), 452-458, 2008 | 211 | 2008 |
| Variations in gene and protein expression in human nucleus pulposus in comparison with annulus fibrosus and cartilage cells: potential associations with aging and degeneration J Rutges, LB Creemers, W Dhert, S Milz, D Sakai, J Mochida, M Alini, ... Osteoarthritis and Cartilage 18 (3), 416-423, 2010 | 183 | 2010 |
| Enhancement of intervertebral disc cell senescence by WNT/β‐catenin signaling–induced matrix metalloproteinase expression A Hiyama, D Sakai, MV Risbud, M Tanaka, F Arai, K Abe, J Mochida Arthritis & Rheumatism 62 (10), 3036-3047, 2010 | 181 | 2010 |
| Risk factors for surgical site infection following spine surgery: efficacy of intraoperative saline irrigation M Watanabe, D Sakai, D Matsuyama, Y Yamamoto, M Sato, J Mochida Journal of Neurosurgery: Spine 12 (5), 540-546, 2010 | 171 | 2010 |
| Differential phenotype of intervertebral disc cells: microarray and immunohistochemical analysis of canine nucleus pulposus and anulus fibrosus D Sakai, T Nakai, J Mochida, M Alini, S Grad Spine 34 (14), 1448-1456, 2009 | 170 | 2009 |
