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Jennifer Leight
Jennifer Leight
Associate Professor of Practice, Department of Biomedical Engineering, The Ohio State University
Bestätigte E-Mail-Adresse bei osu.edu - Startseite
Titel
Zitiert von
Zitiert von
Jahr
Matrix rigidity regulates a switch between TGF-β1–induced apoptosis and epithelial–mesenchymal transition
JL Leight, MA Wozniak, S Chen, ML Lynch, CS Chen
Molecular biology of the cell 23 (5), 781-791, 2012
5042012
Negative normal stress in semiflexible biopolymer gels
PA Janmey, ME McCormick, S Rammensee, JL Leight, PC Georges, ...
Nature materials 6 (1), 48-51, 2007
4582007
Development of a cellularly degradable PEG hydrogel to promote articular cartilage extracellular matrix deposition
BV Sridhar, JL Brock, JS Silver, JL Leight, MA Randolph, KS Anseth
Advanced healthcare materials 4 (5), 702-713, 2015
2022015
Filamin A–β1 integrin complex tunes epithelial cell response to matrix tension
S Gehler, M Baldassarre, Y Lad, JL Leight, MA Wozniak, KM Riching, ...
Molecular biology of the cell 20 (14), 3224-3238, 2009
1462009
Extracellular matrix remodeling and stiffening modulate tumor phenotype and treatment response
JL Leight, AP Drain, VM Weaver
Annual Review of Cancer Biology 1, 313-334, 2017
1312017
Demystifying the effects of a three‐dimensional microenvironment in tissue morphogenesis
KR Johnson, JL Leight, VM Weaver
Methods in cell biology 83, 547-583, 2007
1182007
Direct measurement of matrix metalloproteinase activity in 3D cellular microenvironments using a fluorogenic peptide substrate
JL Leight, DL Alge, AJ Maier, KS Anseth
Biomaterials 34 (30), 7344-7352, 2013
962013
Modulation of matrix elasticity with PEG hydrogels to study melanoma drug responsiveness
EY Tokuda, JL Leight, KS Anseth
Biomaterials 35 (14), 4310-4318, 2014
712014
Multifunctional bioscaffolds for 3D culture of melanoma cells reveal increased MMP activity and migration with BRAF kinase inhibition
JL Leight, EY Tokuda, CE Jones, AJ Lin, KS Anseth
Proceedings of the National Academy of Sciences 112 (17), 5366-5371, 2015
692015
Stromal PTEN regulates extracellular matrix organization in the mammary gland
CE Jones, AM Hammer, YJ Cho, GM Sizemore, E Cukierman, LD Yee, ...
Neoplasia 21 (1), 132-145, 2019
452019
Synthesis of microgel sensors for spatial and temporal monitoring of protease activity
DS Shin, EY Tokuda, JL Leight, CE Miksch, TE Brown, KS Anseth
ACS biomaterials science & engineering 4 (2), 378-387, 2018
432018
Matrix compliance permits NF-κB activation to drive therapy resistance in breast cancer
AP Drain, N Zahir, JJ Northey, H Zhang, PJ Huang, O Maller, JN Lakins, ...
Journal of Experimental Medicine 218 (5), e20191360, 2021
382021
MDM2 Derived from Dedifferentiated Liposarcoma Extracellular Vesicles Induces MMP2 Production from Preadipocytes
L Casadei, F Calore, DA Braggio, A Zewdu, AA Deshmukh, P Fadda, ...
Cancer research 79 (19), 4911-4922, 2019
312019
Matrix-metalloproteinase expression and gelatinase activity in the avian retina and their influence on Müller glia proliferation
WA Campbell IV, A Deshmukh, S Blum, L Todd, N Mendonca, J Weist, ...
Experimental neurology 320, 112984, 2019
262019
In utero estrogenic endocrine disruption alters the stroma to increase extracellular matrix density and mammary gland stiffness
C Wormsbaecher, AR Hindman, A Avendano, M Cortes-Medina, ...
Breast Cancer Research 22, 1-12, 2020
182020
Manipulation of 3D cluster size and geometry by release from 2D micropatterns
JL Leight, WF Liu, RR Chaturvedi, S Chen, MT Yang, S Raghavan, ...
Cellular and molecular bioengineering 5, 299-306, 2012
182012
Myoferlin regulates epithelial cancer cell plasticity and migration through autocrine TGF-β1 signaling
VR Barnhouse, JL Weist, VC Shukla, SN Ghadiali, DA Kniss, JL Leight
Oncotarget 9 (27), 19209, 2018
162018
Detection of proteolytic activity by covalent tethering of fluorogenic substrates in zymogram gels
AA Deshmukh, JL Weist, JL Leight
BioTechniques 64 (5), 203-210, 2018
152018
Cellular mechanics of primary human cervical fibroblasts: influence of progesterone and a pro-inflammatory cytokine
V Shukla, V Barnhouse, WE Ackerman, TL Summerfield, HM Powell, ...
Annals of Biomedical Engineering 46, 197-207, 2018
132018
Tissue engineering: development of a cellularly degradable PEG hydrogel to promote articular cartilage extracellular matrix deposition (Adv. Healthcare Mater. 5/2015)
BV Sridhar, JL Brock, JS Silver, JL Leight, MA Randolph, KS Anseth
Advanced healthcare materials 4 (5), 635-635, 2015
132015
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