Rob Klose
Rob Klose
Professor and Chair of Genetics, University of Oxford.
Verified email at - Homepage
Cited by
Cited by
Genomic DNA methylation: the mark and its mediators
RJ Klose, AP Bird
Trends in biochemical sciences 31 (2), 89-97, 2006
JmjC-domain-containing proteins and histone demethylation
RJ Klose, EM Kallin, Y Zhang
Nature reviews genetics 7 (9), 715-727, 2006
The oncometabolite 2‐hydroxyglutarate inhibits histone lysine demethylases
R Chowdhury, KK Yeoh, YM Tian, L Hillringhaus, EA Bagg, NR Rose, ...
EMBO reports 12 (5), 463-469, 2011
Regulation of histone methylation by demethylimination and demethylation
RJ Klose, Y Zhang
Nature reviews Molecular cell biology 8 (4), 307-318, 2007
The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36
RJ Klose, K Yamane, Y Bae, D Zhang, H Erdjument-Bromage, P Tempst, ...
Nature 442 (7100), 312-316, 2006
Variant PRC1 complex-dependent H2A ubiquitylation drives PRC2 recruitment and polycomb domain formation
NP Blackledge, AM Farcas, T Kondo, HW King, JF McGouran, ...
Cell 157 (6), 1445-1459, 2014
Understanding the relationship between DNA methylation and histone lysine methylation
NR Rose, RJ Klose
Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1839 (12 …, 2014
PLU-1 is an H3K4 demethylase involved in transcriptional repression and breast cancer cell proliferation
K Yamane, K Tateishi, RJ Klose, J Fang, LA Fabrizio, ...
Molecular cell 25 (6), 801-812, 2007
The retinoblastoma binding protein RBP2 is an H3K4 demethylase
RJ Klose, Q Yan, Z Tothova, K Yamane, H Erdjument-Bromage, P Tempst, ...
Cell 128 (5), 889-900, 2007
KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands
AM Farcas, NP Blackledge, I Sudbery, HK Long, JF McGouran, NR Rose, ...
elife 1, e00205, 2012
DNA binding selectivity of MeCP2 due to a requirement for A/T sequences adjacent to methyl-CpG
RJ Klose, SA Sarraf, L Schmiedeberg, SM McDermott, I Stancheva, ...
Molecular cell 19 (5), 667-678, 2005
Targeting Polycomb systems to regulate gene expression: modifications to a complex story
NP Blackledge, NR Rose, RJ Klose
Nature reviews Molecular cell biology 16 (11), 643-649, 2015
CpG islands recruit a histone H3 lysine 36 demethylase
NP Blackledge, JC Zhou, MY Tolstorukov, AM Farcas, PJ Park, RJ Klose
Molecular cell 38 (2), 179-190, 2010
Targeting polycomb to pericentric heterochromatin in embryonic stem cells reveals a role for H2AK119u1 in PRC2 recruitment
S Cooper, M Dienstbier, R Hassan, L Schermelleh, J Sharif, ...
Cell reports 7 (5), 1456-1470, 2014
Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators
D Landeira, S Sauer, R Poot, M Dvorkina, L Mazzarella, HF Jørgensen, ...
Nature cell biology 12 (6), 618-624, 2010
MeCP2 binding to DNA depends upon hydration at methyl-CpG
KL Ho, IW McNae, L Schmiedeberg, RJ Klose, AP Bird, MD Walkinshaw
Molecular cell 29 (4), 525-531, 2008
ZF-CxxC domain-containing proteins, CpG islands and the chromatin connection
HK Long, NP Blackledge, RJ Klose
Biochemical Society Transactions 41 (3), 727-740, 2013
Dynamic protein methylation in chromatin biology
SS Ng, WW Yue, U Oppermann, RJ Klose
Cellular and Molecular Life Sciences 66, 407-422, 2009
Phosphorylation of MeCP2 at Serine 80 regulates its chromatin association and neurological function
J Tao, K Hu, Q Chang, H Wu, NE Sherman, K Martinowich, RJ Klose, ...
Proceedings of the National Academy of Sciences 106 (12), 4882-4887, 2009
Quantitative high-throughput screening identifies 8-hydroxyquinolines as cell-active histone demethylase inhibitors
ONF King, XS Li, M Sakurai, A Kawamura, NR Rose, SS Ng, AM Quinn, ...
PloS one 5 (11), e15535, 2010
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