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Jaesung Peter Choi
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Endothelial TLR4 and the microbiome drive cerebral cavernous malformations
AT Tang, JP Choi, JJ Kotzin, Y Yang, CC Hong, N Hobson, R Girard, ...
Nature 545 (7654), 305-310, 2017
2822017
The role of the microbiome and the NLRP3 inflammasome in the gut and lung
C Donovan, G Liu, S Shen, JE Marshall, RY Kim, CA Alamao, KF Budden, ...
Journal of Leukocyte Biology, 2020
672020
Ponatinib (AP24534) inhibits MEKK3-KLF signaling and prevents formation and progression of cerebral cavernous malformations
JP Choi, R Wang, X Yang, X Wang, L Wang, KK Ting, M Foley, V Cogger, ...
Science advances 4 (11), eaau0731, 2018
472018
Low fluid shear stress conditions contribute to activation of cerebral cavernous malformation signalling pathways
J Li, Y Zhao, P Coleman, J Chen, KK Ting, JP Choi, X Zheng, MA Vadas, ...
Biochimica Et Biophysica Acta (BBA)-Molecular Basis of Disease 1865 (11), 165519, 2019
382019
Cerebral cavernous malformations are driven by ADAMTS5 proteolysis of versican
CC Hong, AT Tang, MR Detter, JP Choi, R Wang, X Yang, AA Guerrero, ...
Journal of Experimental Medicine 217 (10), e20200140, 2020
312020
Targeting miR-27a/VE-cadherin interactions rescues cerebral cavernous malformations in mice
J Li, Y Zhao, J Choi, KK Ting, P Coleman, J Chen, VC Cogger, L Wan, ...
PLoS biology 18 (6), e3000734, 2020
302020
Development and characterization of uterine glandular epithelium specific androgen receptor knockout mouse model
JP Choi, Y Zheng, KA Skulte, DJ Handelsman, U Simanainen
Biology of Reproduction 93 (5), 120, 1-11, 2015
242015
Micro-CT Imaging Reveals Mekk3 Heterozygosity Prevents Cerebral Cavernous Malformations in Ccm2-Deficient Mice
JP Choi, M Foley, Z Zhou, WY Wong, N Gokoolparsadh, JSC Arthur, DY Li, ...
PLoS One 11 (8), e0160833, 2016
182016
Induction and micro-CT imaging of cerebral cavernous malformations in mouse model
JP Choi, X Yang, M Foley, X Wang, X Zheng
JoVE (Journal of Visualized Experiments), e56476, 2017
152017
The role of androgens in experimental rodent mammary carcinogenesis
J Choi, B Psarommatis, YR Gao, Y Zheng, DJ Handelsman, ...
Breast Cancer Research 16, 1-12, 2014
152014
Pdcd10-Stk24/25 complex controls kidney water reabsorption by regulating Aqp2 membrane targeting
R Wang, ST Wu, X Yang, Y Qian, JP Choi, R Gao, S Song, Y Wang, ...
JCI insight 6 (12), 2021
142021
Blood-spinal cord barrier: its role in spinal disorders and emerging therapeutic strategies
N Chopra, S Menounos, JP Choi, PM Hansbro, AD Diwan, A Das
NeuroSci 3 (1), 1-27, 2021
132021
Androgen actions via androgen receptor promote PTEN inactivation induced uterine cancer
JP Choi, R Desai, Y Zheng, M Yao, Q Dong, G Watson, DJ Handelsman, ...
Endocr. Relat. Cancer 22, 687-701, 2015
102015
Glucocorticoid receptor in prostate epithelia is not required for corticosteroid‐induced epithelial hyperproliferation in the mouse prostate
B Zhao, J Choi, M Jaehne, YR Gao, R Desai, J Tuckermann, H Zhou, ...
The Prostate 74 (10), 1068-1078, 2014
102014
CCM2L (Cerebral Cavernous Malformation 2 Like) deletion aggravates cerebral cavernous malformation through Map3k3-KLF signaling pathway
JP Choi, X Yang, S He, R Song, ZR Xu, M Foley, JJL Wong, CR Xu, ...
Stroke 52 (4), 1428-1436, 2021
32021
Glandular epithelial AR inactivation enhances PTEN deletion-induced uterine pathology
JP Choi, Y Zheng, DJ Handelsman, U Simanainen
Endocrine-Related Cancer 23 (5), 377-390, 2016
22016
Generation of cerebral cavernous malformation in neonatal mouse models using inducible Cre-LoxP strategy
JP Choi, X Zheng
Cerebral Cavernous Malformations (CCM) Methods and Protocols, 253-258, 2020
12020
Targeting PKM2 signaling cascade with salvianic acid A normalizes tumor blood vessels to facilitate chemotherapeutic drug delivery
C Qian, Y Zhou, T Zhang, G Dong, M Song, Y Tang, Z Wei, S Yu, Q Shen, ...
Acta Pharmaceutica Sinica B, 2024
2024
The role of androgens acting via androgen receptor in uterine development and PTEN deletion induced uterine cancer
JP Choi
University of Sydney, 2016
2016
Androgen Receptor Inactivation Reduces PTEN Inactivation Induced Endometrial Cancer By Decreasing Estrogen Sensitivity
JP Choi, R Desai, DJ Handelsman, UK Simanainen
ENDOCRINE REVIEWS 35 (3), 2014
2014
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