| New aspects on the melanocortins and their receptors JES Wikberg, R Muceniece, I Mandrika, P Prusis, J Lindblom, C Post, ... Pharmacological research 42 (5), 393-420, 2000 | 447 | 2000 |
| Discovery of novel melanocortin4 receptor selective MSH analogues HB Schiöth, F Mutulis, R Muceniece, P Prusis, JES Wikberg British journal of pharmacology 124 (1), 75-82, 1998 | 176 | 1998 |
| Development of proteo-chemometrics: a novel technology for the analysis of drug-receptor interactions M Lapinsh, P Prusis, A Gutcaits, T Lundstedt, JES Wikberg Biochimica et Biophysica Acta (BBA)-General Subjects 1525 (1-2), 180-190, 2001 | 166 | 2001 |
| Classification of G‐protein coupled receptors by alignment‐independent extraction of principal chemical properties of primary amino acid sequences M Lapinsh, A Gutcaits, P Prusis, C Post, T Lundstedt, JES Wikberg Protein Science 11 (4), 795-805, 2002 | 133 | 2002 |
| Polypharmacology modelling using proteochemometrics (PCM): recent methodological developments, applications to target families, and future prospects I Cortés-Ciriano, QU Ain, V Subramanian, EB Lenselink, O Méndez-Lucio, ... MedChemComm 6 (1), 24-50, 2015 | 123 | 2015 |
| Evaluation of the human prediction of clearance from hepatocyte and microsome intrinsic clearance for 52 drug compounds AK Sohlenius-Sternbeck, L Afzelius, P Prusis, J Neelissen, J Hoogstraate, ... Xenobiotica 40 (9), 637-649, 2010 | 117 | 2010 |
| Selectivity of cyclic [D-Nal7] and [D-Phe7] substituted MSH analogues for the melanocortin receptor subtypes HB Schiöth, R Muceniece, F Mutulis, P Prusis, G Lindeberg, SD Sharma, ... Peptides 18 (7), 1009-1013, 1997 | 106 | 1997 |
| Proteochemometrics modeling of the interaction of amine G-protein coupled receptors with a diverse set of ligands M Lapinsh, P Prusis, T Lundstedt, JES Wikberg Molecular pharmacology 61 (6), 1465-1475, 2002 | 103 | 2002 |
| Long term orexigenic effect of a novel melanocortin 4 receptor selective antagonist GV Skuladottir, L Jonsson, JO Skarphedinsson, F Mutulis, R Muceniece, ... British journal of pharmacology 126 (1), 27, 1999 | 100 | 1999 |
| Improved approach for proteochemometrics modeling: application to organic compound—amine G protein-coupled receptor interactions M Lapinsh, P Prusis, S Uhlén, JES Wikberg Bioinformatics 21 (23), 4289-4296, 2005 | 97 | 2005 |
| Proteochemometric modeling of HIV protease susceptibility M Lapins, M Eklund, O Spjuth, P Prusis, JES Wikberg BMC bioinformatics 9, 1-11, 2008 | 90 | 2008 |
| Modeling of the three-dimensional structure of the human melanocortin 1 receptor, using an automated method and docking of a rigid cyclic melanocyte-stimulating hormone core … P Prusis, HB Schiöth, R Muceniece, P Herzyk, M Afshar, RE Hubbard, ... Journal of Molecular Graphics and Modelling 15 (5), 307-317, 1997 | 90 | 1997 |
| A three-dimensional model for the interaction of MSH with the melanocortin-1 receptor P Prusis, PA Frandberg, R Muceniece, I Kalvinsh, JES Wikberg Biochemical and biophysical research communications 210 (1), 205-210, 1995 | 85 | 1995 |
| Evidence for Alternate Points of Attachment for α-MSH and Its Stereoisomer (Nle4, D-Phe7)-α-MSH at the Melanocortin-1 Receptor PA Frandberg, R Muceniece, P Prusis, J Wikberg, V Chhajlani Biochemical and biophysical research communications 202 (3), 1266-1271, 1994 | 74 | 1994 |
| Probing the substrate specificity of the dengue virus type 2 NS3 serine protease by using internally quenched fluorescent peptides P Niyomrattanakit, S Yahorava, I Mutule, F Mutulis, R Petrovska, P Prusis, ... Biochemical Journal 397 (1), 203-211, 2006 | 66 | 2006 |
| PLS modeling of chimeric MS04/MSH-peptide and MC1/MC3-receptor interactions reveals a novel method for the analysis of ligand–receptor interactions P Prusis, R Muceniece, P Andersson, C Post, T Lundstedt, JES Wikberg Biochimica et Biophysica Acta (BBA)-Protein Structure and Molecular …, 2001 | 66 | 2001 |
| Binding of cyclic and linear MSH core peptides to the melanocortin receptor subtypes HB Schiöth, R Muceniece, M Larsson, F Mutulis, M Szardenings, P Prusis, ... European journal of pharmacology 319 (2-3), 369-373, 1997 | 63 | 1997 |
| Proteochemometrics: a tool for modeling the molecular interaction space JES Wikberg, M Lapinsh, P Prusis Chemogenomics in drug discovery: a medicinal chemistry perspective, 289-309, 2004 | 59 | 2004 |
| Proteochemometrics analysis of substrate interactions with dengue virus NS3 proteases P Prusis, M Lapins, S Yahorava, R Petrovska, P Niyomrattanakit, ... Bioorganic & medicinal chemistry 16 (20), 9369-9377, 2008 | 57 | 2008 |
| QSAR and proteo-chemometric analysis of the interaction of a series of organic compounds with melanocortin receptor subtypes M Lapinsh, P Prusis, I Mutule, F Mutulis, JES Wikberg Journal of medicinal chemistry 46 (13), 2572-2579, 2003 | 55 | 2003 |
