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Thomas Balle
Thomas Balle
Professor, Sydney Pharmacy School, The University of Sydney
Bestätigte E-Mail-Adresse bei sydney.edu.au
Titel
Zitiert von
Zitiert von
Jahr
Open3DQSAR: a new open-source software aimed at high-throughput chemometric analysis of molecular interaction fields
P Tosco, T Balle
Journal of molecular modeling 17, 201-208, 2011
1772011
Unraveling the high-and low-sensitivity agonist responses of nicotinic acetylcholine receptors
K Harpsøe, PK Ahring, JK Christensen, ML Jensen, D Peters, T Balle
Journal of Neuroscience 31 (30), 10759-10766, 2011
1612011
Open3DALIGN: an open-source software aimed at unsupervised ligand alignment
P Tosco, T Balle, F Shiri
Journal of computer-aided molecular design 25, 777-783, 2011
1342011
A Unified Model of the GABAA Receptor Comprising Agonist and Benzodiazepine Binding Sites
R Bergmann, K Kongsbak, PL Sørensen, T Sander, T Balle
PloS one 8 (1), e52323, 2013
1222013
Synthesis and Structure− Affinity Relationship Investigations of 5-Heteroaryl-Substituted Analogues of the Antipsychotic Sertindole. A New Class of Highly Selective α1 …
T Balle, J Perregaard, MT Ramirez, AK Larsen, KK Søby, T Liljefors, ...
Journal of medicinal chemistry 46 (2), 265-283, 2003
782003
GABAA receptor partial agonists and antagonists: structure, binding mode, and pharmacology
J Krall, T Balle, N Krogsgaard-Larsen, TE Sørensen, ...
Advances in pharmacology 72, 201-227, 2015
592015
Liquid lipases for enzymatic concentration of n-3 polyunsaturated fatty acids in monoacylglycerols via ethanolysis: Catalytic specificity and parameterization
Y He, J Li, S Kodali, T Balle, B Chen, Z Guo
Bioresource Technology 224, 445-456, 2017
582017
Innate immunity and inflammation post-stroke: an α7-nicotinic agonist perspective
S Neumann, NJ Shields, T Balle, M Chebib, AN Clarkson
International Journal of Molecular Sciences 16 (12), 29029-29046, 2015
582015
Rational design of α-conotoxin analogues targeting α7 nicotinic acetylcholine receptors
C Armishaw, AA Jensen, T Balle, RJ Clark, K Harpsøe, C Skonberg, ...
Journal of biological chemistry 284 (14), 9498-9512, 2009
582009
Design, synthesis, and biological evaluation of Erythrina alkaloid analogues as neuronal nicotinic acetylcholine receptor antagonists
F Crestey, AA Jensen, M Borch, JT Andreasen, J Andersen, T Balle, ...
Journal of Medicinal Chemistry 56 (23), 9673-9682, 2013
552013
Intersubunit bridge formation governs agonist efficacy at nicotinic acetylcholine α4β2 receptors
LAH Rohde, PK Ahring, ML Jensen, EØ Nielsen, D Peters, C Helgstrand, ...
Journal of Biological Chemistry 287 (6), 4248-4259, 2012
542012
Molecular recognition of the neurotransmitter acetylcholine by an acetylcholine binding protein reveals determinants of binding to nicotinic acetylcholine receptors
JA Olsen, T Balle, M Gajhede, PK Ahring, JS Kastrup
PloS one 9 (3), e91232, 2014
512014
Two distinct allosteric binding sites at α4β2 nicotinic acetylcholine receptors revealed by NS206 and NS9283 give unique insights to binding activity-associated linkage at Cys …
JA Olsen, JS Kastrup, D Peters, M Gajhede, T Balle, PK Ahring
Journal of Biological Chemistry 288 (50), 35997-36006, 2013
512013
G Protein- and Agonist-Bound Serotonin 5-HT2A Receptor Model Activated by Steered Molecular Dynamics Simulations
V Ísberg, T Balle, T Sander, FS Jørgensen, DE Gloriam
Journal of chemical information and modeling 51 (2), 315-325, 2011
502011
Structural studies of nicotinic acetylcholine receptors: Using acetylcholine‐binding protein as a structural surrogate
A Shahsavar, M Gajhede, JS Kastrup, T Balle
Basic & clinical pharmacology & toxicology 118 (6), 399-407, 2016
472016
Crystal Structure of Lymnaea stagnalis AChBP Complexed with the Potent nAChR Antagonist DHβE Suggests a Unique Mode of Antagonism
A Shahsavar, JS Kastrup, EØ Nielsen, JL Kristensen, M Gajhede, T Balle
Public Library of Science 7 (8), e40757, 2012
472012
Galantamine is not a positive allosteric modulator of human α4β2 or α7 nicotinic acetylcholine receptors
NM Kowal, PK Ahring, VWY Liao, DC Indurti, BS Harvey, SM O'Connor, ...
British journal of pharmacology 175 (14), 2911-2925, 2018
462018
Probing the role of backbone hydrogen bonds in protein–peptide interactions by amide-to-ester mutations
JNN Eildal, G Hultqvist, T Balle, N Stuhr-Hansen, S Padrah, S Gianni, ...
Journal of the American Chemical Society 135 (35), 12998-13007, 2013
462013
New insights into the GABAA receptor structure and orthosteric ligand binding: Receptor modeling guided by experimental data
T Sander, B Frølund, AT Bruun, I Ivanov, JA McCammon, T Balle
Proteins: Structure, Function, and Bioinformatics 79 (5), 1458-1477, 2011
462011
Structural and functional studies of the modulator NS9283 reveal agonist-like mechanism of action at α4β2 nicotinic acetylcholine receptors
JA Olsen, PK Ahring, JS Kastrup, M Gajhede, T Balle
Journal of Biological Chemistry 289 (36), 24911-24921, 2014
422014
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