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Ajamete Kaykas
Ajamete Kaykas
Novartis Institutes for Biomedical Research
Verified email at novartis.com - Homepage
Title
Cited by
Cited by
Year
WNT and β-catenin signalling: diseases and therapies
RT Moon, AD Kohn, GVD Ferrari, A Kaykas
Nature reviews genetics 5 (9), 691-701, 2004
22352004
Zebrafish prickle, a modulator of noncanonical Wnt/Fz signaling, regulates gastrulation movements
MT Veeman, DC Slusarski, A Kaykas, SH Louie, RT Moon
Current biology 13 (8), 680-685, 2003
10512003
p53 inhibits CRISPR–Cas9 engineering in human pluripotent stem cells
RJ Ihry, KA Worringer, MR Salick, E Frias, D Ho, K Theriault, S Kommineni, ...
Nature medicine 24 (7), 939-946, 2018
9252018
Increased synapse elimination by microglia in schizophrenia patient-derived models of synaptic pruning
CM Sellgren, J Gracias, B Watmuff, JD Biag, JM Thanos, PB Whittredge, ...
Nature neuroscience 22 (3), 374-385, 2019
6142019
Mutant frizzled-4 disrupts retinal angiogenesis in familial exudative vitreoretinopathy
J Robitaille, MLE MacDonald, A Kaykas, LC Sheldahl, J Zeisler, MP Dubé, ...
Nature genetics 32 (2), 326-330, 2002
5412002
A viral strategy for targeting and manipulating interneurons across vertebrate species
J Dimidschstein, Q Chen, R Tremblay, SL Rogers, GA Saldi, L Guo, Q Xu, ...
Nature neuroscience 19 (12), 1743-1749, 2016
4522016
Functional genomic analysis of the Wnt-wingless signaling pathway
R DasGupta, A Kaykas, RT Moon, N Perrimon
Science 308 (5723), 826-833, 2005
4152005
Genetic ablation of AXL does not protect human neural progenitor cells and cerebral organoids from Zika virus infection
MF Wells, MR Salick, O Wiskow, DJ Ho, KA Worringer, RJ Ihry, ...
Cell stem cell 19 (6), 703-708, 2016
2872016
A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain
CL Thompson, L Ng, V Menon, S Martinez, CK Lee, K Glattfelder, ...
Neuron 83 (2), 309-323, 2014
2682014
CORTECON: a temporal transcriptome analysis of in vitro human cerebral cortex development from human embryonic stem cells
J Van De Leemput, NC Boles, TR Kiehl, B Corneo, P Lederman, V Menon, ...
Neuron 83 (1), 51-68, 2014
2112014
Mutant Frizzled 4 associated with vitreoretinopathy traps wild-type Frizzled in the endoplasmic reticulum by oligomerization
A Kaykas, J Yang-Snyder, M Héroux, KV Shah, M Bouvier, RT Moon
Nature cell biology 6 (1), 52-58, 2004
1992004
DRUG-seq for miniaturized high-throughput transcriptome profiling in drug discovery
C Ye, DJ Ho, M Neri, C Yang, T Kulkarni, R Randhawa, M Henault, ...
Nature communications 9 (1), 4307, 2018
1592018
A single-cell roadmap of lineage bifurcation in human ESC models of embryonic brain development
Z Yao, JK Mich, S Ku, V Menon, AR Krostag, RA Martinez, L Furchtgott, ...
Cell stem cell 20 (1), 120-134, 2017
1372017
CD40 and LMP-1 both signal from lipid rafts but LMP-1 assembles a distinct, more efficient signaling complex
A Kaykas, K Worringer, B Sugden
The EMBO journal 20 (11), 2641-2654, 2001
1282001
A plasmid-based system for expressing small interfering RNA libraries in mammalian cells
A Kaykas, RT Moon
BMC Cell Biology 5, 1-11, 2004
1152004
ADAM17 is the main sheddase for the generation of human triggering receptor expressed in myeloid cells (hTREM2) ectodomain and cleaves TREM2 after Histidine 157
D Feuerbach, P Schindler, C Barske, S Joller, E Beng-Louka, ...
Neuroscience letters 660, 109-114, 2017
1012017
The amino-terminus and membrane-spanning domains of LMP-1 inhibit cell proliferation
A Kaykas, B Sugden
Oncogene 19 (11), 1400-1410, 2000
972000
Creating patient-specific neural cells for the in vitro study of brain disorders
KJ Brennand, MC Marchetto, N Benvenisty, O Brüstle, A Ebert, ...
Stem cell reports 5 (6), 933-945, 2015
842015
Genome-scale CRISPR screens identify human pluripotency-specific genes
RJ Ihry, MR Salick, DJ Ho, M Sondey, S Kommineni, S Paula, J Raymond, ...
Cell reports 27 (2), 616-630. e6, 2019
722019
P53 toxicity is a hurdle to CRISPR/CAS9 screening and engineering in human pluripotent stem cells
RJ Ihry, KA Worringer, MR Salick, E Frias, D Ho, K Theriault, S Kommineni, ...
bioRxiv, 168443, 2017
562017
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