TRPM2-mediated Ca2+ influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration S Yamamoto, S Shimizu, S Kiyonaka, N Takahashi, T Wajima, Y Hara, ... Nature medicine 14 (7), 738-747, 2008 | 652 | 2008 |
TRPM2 functions as a lysosomal Ca2+-release channel in β cells I Lange, S Yamamoto, S Partida-Sanchez, Y Mori, A Fleig, R Penner Science signaling 2 (71), ra23-ra23, 2009 | 318 | 2009 |
A minimal regulatory domain in the C terminus of STIM1 binds to and activates ORAI1 CRAC channels T Kawasaki, I Lange, S Feske Biochemical and biophysical research communications 385 (1), 49-54, 2009 | 300 | 2009 |
Protein kinase C-induced phosphorylation of Orai1 regulates the intracellular Ca2+ level via the store-operated Ca2+ channel T Kawasaki, T Ueyama, I Lange, S Feske, N Saito Journal of Biological Chemistry 285 (33), 25720-25730, 2010 | 160 | 2010 |
Dendritic cell maturation and chemotaxis is regulated by TRPM2-mediated lysosomal Ca2+ release A Sumoza-Toledo, I Lange, H Cortado, H Bhagat, Y Mori, A Fleig, ... The FASEB Journal 25 (10), 3529, 2011 | 151 | 2011 |
Synergistic regulation of endogenous TRPM2 channels by adenine dinucleotides in primary human neutrophils I Lange, R Penner, A Fleig, A Beck Cell calcium 44 (6), 604-615, 2008 | 134 | 2008 |
TRPM2 ion channels regulate macrophage polarization and gastric inflammation during Helicobacter pylori infection S Beceiro, JN Radin, R Chatuvedi, MB Piazuelo, DJ Horvarth, H Cortado, ... Mucosal immunology 10 (2), 493-507, 2017 | 64 | 2017 |
DFMO/eflornithine inhibits migration and invasion downstream of MYCN and involves p27Kip1 activity in neuroblastoma DLT Koomoa, D Geerts, I Lange, J Koster, AE Pegg, DJ Feith, ... International journal of oncology 42 (4), 1219-1228, 2013 | 63 | 2013 |
Novel interaction of ornithine decarboxylase with sepiapterin reductase regulates neuroblastoma cell proliferation I Lange, D Geerts, DJ Feith, G Mocz, J Koster, AS Bachmann Journal of molecular biology 426 (2), 332-346, 2014 | 31 | 2014 |
STIM1 and STIM2 mediate cancer-induced inflammation in T cell acute lymphoblastic leukemia S Saint Fleur-Lominy, M Maus, M Vaeth, I Lange, I Zee, D Suh, C Liu, ... Cell reports 24 (11), 3045-3060. e5, 2018 | 27 | 2018 |
MycN promotes TRPM7 expression and cell migration in neuroblastoma through a process that involves polyamines I Lange, DLT Koomoa FEBS open Bio 4, 966-975, 2014 | 16 | 2014 |
In vitro efficacy of anthelmintics on Angiostrongylus cantonensis L3 larvae J Jacob, G Tan, I Lange, H Saeed, A Date, S Jarvi Parasitology 148 (2), 240-250, 2021 | 15 | 2021 |
Synthesis and characterization of lipophilic salts of metformin to improve its repurposing for cancer therapy HK Saeed, Y Sutar, P Patel, R Bhat, S Mallick, AE Hatada, DLT Koomoa, ... ACS omega 6 (4), 2626-2637, 2021 | 15 | 2021 |
Validation of a death assay for Angiostrongylus cantonensis larvae (L3) using propidium iodide in a rat model (Rattus norvegicus) SI Jarvi, J Jacob, RT Sugihara, IL Leinbach, IH Klasner, LM Kaluna, ... Parasitology 146 (11), 1421-1428, 2019 | 15 | 2019 |
FTY-720 induces apoptosis in neuroblastoma via multiple signaling pathways I Lange, I Espinoza-Fuenzalida, MW Ali, LE Serrano, DLT Koomoa Oncotarget 8 (66), 109985, 2017 | 15 | 2017 |
Calcium signaling regulates fundamental processes involved in Neuroblastoma progression I Lange, J Koster, DLT Koomoa Cell calcium 82, 102052, 2019 | 13 | 2019 |
Scrophularia orientalis extract induces calcium signaling and apoptosis in neuroblastoma cells I Lange, J Moschny, K Tamanyan, M Khutsishvili, D Atha, RP Borris, ... International Journal of Oncology 48 (4), 1608-1616, 2016 | 10 | 2016 |
Potential anti-neuroblastoma agents from Juniperus oblonga Y Qiao, NK Sunada, AE Hatada, I Lange, M Khutsishvili, V Alizade, D Atha, ... Biochemical and biophysical research communications 516 (3), 733-738, 2019 | 5 | 2019 |
Differential Regulation of Calcium Signalling Pathways by Components of Piper methysticum ('Awa) LMN Shimoda, A Showman, JD Baker, I Lange, DL Koomoa, AJ Stokes, ... Phytotherapy research 29 (4), 582-590, 2015 | 4 | 2015 |
In vitro exposure to Hymenoptera venom and constituents activates discrete ionotropic pathways in mast cells C Jansen, LMN Shimoda, J Starkus, I Lange, N Rysavy, ... Channels 13 (1), 264-286, 2019 | 2 | 2019 |