| Adrenergic nervous system in heart failure: pathophysiology and therapy A Lymperopoulos, G Rengo, WJ Koch Circulation research 113 (6), 739-753, 2013 | 706 | 2013 |
| Adrenal GRK2 upregulation mediates sympathetic overdrive in heart failure A Lymperopoulos, G Rengo, H Funakoshi, AD Eckhart, WJ Koch Nature medicine 13 (3), 315-323, 2007 | 280 | 2007 |
| Myocardial adeno-associated virus serotype 6–βARKct gene therapy improves cardiac function and normalizes the neurohormonal axis in chronic heart failure G Rengo, A Lymperopoulos, C Zincarelli, M Donniacuo, S Soltys, ... Circulation 119 (1), 89-98, 2009 | 257 | 2009 |
| Pathophysiology of sepsis-related cardiac dysfunction: driven by inflammation, energy mismanagement, or both? K Drosatos, A Lymperopoulos, PJ Kennel, N Pollak, PC Schulze, ... Current heart failure reports 12, 130-140, 2015 | 216 | 2015 |
| Adrenal adrenoceptors in heart failure: fine-tuning cardiac stimulation A Lymperopoulos, G Rengo, WJ Koch Trends in molecular medicine 13 (12), 503-511, 2007 | 173 | 2007 |
| GRK2 as a novel gene therapy target in heart failure G Rengo, A Lymperopoulos, D Leosco, WJ Koch Journal of molecular and cellular cardiology 50 (5), 785-792, 2011 | 156 | 2011 |
| GPCR signaling and cardiac function LA Capote, RM Perez, A Lymperopoulos European journal of pharmacology 763, 143-148, 2015 | 153 | 2015 |
| An adrenal β-arrestin 1-mediated signaling pathway underlies angiotensin II-induced aldosterone production in vitro and in vivo A Lymperopoulos, G Rengo, C Zincarelli, J Kim, S Soltys, WJ Koch Proceedings of the National Academy of Sciences 106 (14), 5825-5830, 2009 | 127 | 2009 |
| Reduction of sympathetic activity via adrenal-targeted GRK2 gene deletion attenuates heart failure progression and improves cardiac function after myocardial infarction A Lymperopoulos, G Rengo, E Gao, SN Ebert, GW Dorn, WJ Koch Journal of biological chemistry 285 (21), 16378-16386, 2010 | 124 | 2010 |
| Negative impact of β-arrestin-1 on post-myocardial infarction heart failure via cardiac and adrenal-dependent neurohormonal mechanisms A Bathgate-Siryk, S Dabul, K Pandya, K Walklett, G Rengo, A Cannavo, ... Hypertension 63 (2), 404-412, 2014 | 114 | 2014 |
| Adrenal GRK2 lowering is an underlying mechanism for the beneficial sympathetic effects of exercise training in heart failure G Rengo, D Leosco, C Zincarelli, M Marchese, G Corbi, D Liccardo, ... American Journal of Physiology-Heart and Circulatory Physiology 298 (6 …, 2010 | 107 | 2010 |
| Modulation of adrenal catecholamine secretion by in vivo gene transfer and manipulation of G protein–coupled receptor kinase-2 activity A Lymperopoulos, G Rengo, C Zincarelli, S Soltys, WJ Koch Molecular Therapy 16 (2), 302-307, 2008 | 103 | 2008 |
| GRK2 inhibition in heart failure: something old, something new A Lymperopoulos, G Rengo, W J Koch Current pharmaceutical design 18 (2), 186-191, 2012 | 92 | 2012 |
| GRK2 blockade with βARKct is essential for cardiac β2-adrenergic receptor signaling towards increased contractility NC Salazar, X Vallejos, A Siryk, G Rengo, A Cannavo, D Liccardo, ... Cell Communication and Signaling 11, 1-10, 2013 | 91 | 2013 |
| Adrenal beta-arrestin 1 inhibition in vivo attenuates post-myocardial infarction progression to heart failure and adverse remodeling via reduction of circulating aldosterone levels A Lymperopoulos, G Rengo, C Zincarelli, J Kim, WJ Koch Journal of the American College of Cardiology 57 (3), 356-365, 2011 | 91 | 2011 |
| Cardiomyocyte lipids impair β-adrenergic receptor function via PKC activation K Drosatos, KG Bharadwaj, A Lymperopoulos, S Ikeda, R Khan, Y Hu, ... American Journal of Physiology-Endocrinology and Metabolism 300 (3), E489-E499, 2011 | 89 | 2011 |
| Blockade of β‐adrenoceptors restores the GRK2‐mediated adrenal α2‐adrenoceptor–catecholamine production axis in heart failure G Rengo, A Lymperopoulos, C Zincarelli, GD Femminella, D Liccardo, ... British Journal of Pharmacology 166 (8), 2430-2440, 2012 | 83 | 2012 |
| Targeting the β-adrenergic receptor system through G-protein–coupled receptor kinase 2: a new paradigm for therapy and prognostic evaluation in heart failure: from bench to bedside G Rengo, P Perrone-Filardi, GD Femminella, D Liccardo, C Zincarelli, ... Circulation: Heart Failure 5 (3), 385-391, 2012 | 83 | 2012 |
| Exercise training and β-blocker treatment ameliorate age-dependent impairment of β-adrenergic receptor signaling and enhance cardiac responsiveness to adrenergic stimulation D Leosco, G Rengo, G Iaccarino, A Filippelli, A Lymperopoulos, ... American Journal of Physiology-Heart and Circulatory Physiology 293 (3 …, 2007 | 81 | 2007 |
| β-Arrestin2 Improves Post–Myocardial Infarction Heart Failure via Sarco(endo)plasmic Reticulum Ca2+-ATPase–Dependent Positive Inotropy in Cardiomyocytes KA McCrink, J Maning, A Vu, M Jafferjee, C Marrero, A Brill, ... Hypertension 70 (5), 972-981, 2017 | 77 | 2017 |
