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Hossein Fazelinia, Ph.D.
Hossein Fazelinia, Ph.D.
Principal Bioinformatics Scientist, Children's Hospital of Philadelphia
No verified email
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Cited by
Cited by
Year
Comprehensive multi-omics analysis reveals mitochondrial stress as a central biological hub for spaceflight impact
WA da Silveira, H Fazelinia, SB Rosenthal, EC Laiakis, MS Kim, ...
Cell 183 (5), 1185-1201. e20, 2020
1962020
Sustained release of endothelial progenitor cell-derived extracellular vesicles from shear-thinning hydrogels improves angiogenesis and promotes function after myocardial …
CW Chen, LL Wang, S Zaman, J Gordon, MF Arisi, CM Venkataraman, ...
Cardiovascular research 114 (7), 1029-1040, 2018
1782018
AraC regulatory protein mutants with altered effector specificity
SY Tang, H Fazelinia, PC Cirino
Journal of the American Chemical Society 130 (15), 5267-5271, 2008
1642008
The landscape of transcription errors in eukaryotic cells
JF Gout, W Li, C Fritsch, A Li, S Haroon, L Singh, D Hua, H Fazelinia, ...
Science advances 3 (10), e1701484, 2017
1272017
Computational design of Candida boidinii xylose reductase for altered cofactor specificity
GA Khoury, H Fazelinia, JW Chin, RJ Pantazes, PC Cirino, CD Maranas
Protein Science 18 (10), 2125-2138, 2009
1222009
The pediatric cell atlas: defining the growth phase of human development at single-cell resolution
DM Taylor, BJ Aronow, K Tan, K Bernt, N Salomonis, CS Greene, ...
Developmental cell 49 (1), 10-29, 2019
622019
Multi-omics analysis of multiple missions to space reveal a theme of lipid dysregulation in mouse liver
A Beheshti, K Chakravarty, H Fogle, H Fazelinia, WA Silveira, V Boyko, ...
Scientific Reports 9 (1), 19195, 2019
522019
OptGraft: A computational procedure for transferring a binding site onto an existing protein scaffold
H Fazelinia, PC Cirino, CD Maranas
Protein Science 18 (1), 180-195, 2009
502009
Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts
JW Guarnieri, JM Dybas, H Fazelinia, MS Kim, J Frere, Y Zhang, ...
Science translational medicine 15 (708), eabq1533, 2023
432023
Influence of external mass transfer limitation on apparent kinetic parameters of penicillin G acylase immobilized on nonporous ultrafine silica particles
A Kheirolomoom, F Khorasheh, H Fazelinia
Journal of bioscience and bioengineering 93 (2), 125-129, 2002
362002
Induction of the immunoproteasome subunit Lmp7 links proteostasis and immunity in α-synuclein aggregation disorders
S Ugras, MJ Daniels, H Fazelinia, NS Gould, AK Yocum, KC Luk, E Luna, ...
EBioMedicine 31, 307-319, 2018
352018
Extending Iterative Protein Redesign and Optimization (IPRO) in protein library design for ligand specificity
H Fazelinia, PC Cirino, CD Maranas
Biophysical journal 92 (6), 2120-2130, 2007
352007
Urine proteomics: evaluation of different sample preparation workflows for quantitative, reproducible, and improved depth of analysis
H Ding, H Fazelinia, LA Spruce, DA Weiss, SA Zderic, SH Seeholzer
Journal of proteome research 19 (4), 1857-1862, 2020
332020
Ultrafast Hydrogen Exchange Reveals Specific Structural Events during the Initial Stages of Folding of Cytochrome c
H Fazelinia, M Xu, H Cheng, H Roder
Journal of the American Chemical Society 136 (2), 733-740, 2014
322014
Clarification of penicillin G acylase reaction mechanism
A Kheirolomoom, M Ardjmand, H Fazelinia, A Zakeri
Process Biochemistry 36 (11), 1095-1101, 2001
312001
Designing the substrate specificity of D-hydantoinase using a rational approach
SC Lee, YJ Chang, DM Shin, J Han, MH Seo, H Fazelinia, CD Maranas, ...
Enzyme and Microbial Technology 44 (3), 170-175, 2009
282009
Targeted down regulation of core mitochondrial genes during SARS-CoV-2 infection
JW Guarnieri, JM Dybas, H Fazelinia, MS Kim, J Frere, Y Zhang, ...
BioRxiv, 2022
272022
The E3 ubiquitin ligase Cul4b promotes CD4+ T cell expansion by aiding the repair of damaged DNA
AA Dar, K Sawada, JM Dybas, EK Moser, EL Lewis, E Park, H Fazelinia, ...
PLoS Biology 19 (2), e3001041, 2021
162021
Isolation of penicillin G acylase from Escherichia coli ATCC 11105 by physical and chemical treatments
A Kheirolomoom, M Ardjmand, H Fazelinia, A Zakeri
Biochemical engineering journal 8 (3), 223-227, 2001
162001
Multimodality assessment of heart failure with preserved ejection fraction skeletal muscle reveals differences in the machinery of energy fuel metabolism
P Zamani, EA Proto, N Wilson, H Fazelinia, H Ding, LA Spruce, ...
ESC Heart Failure 8 (4), 2698-2712, 2021
152021
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Articles 1–20