Quantum mechanical predictions of the stereoselectivities of proline-catalyzed asymmetric intermolecular aldol reactions S Bahmanyar, KN Houk, HJ Martin, B List Journal of the American Chemical Society 125 (9), 2475-2479, 2003 | 747 | 2003 |
Kinetic and stereochemical evidence for the involvement of only one proline molecule in the transition states of proline-catalyzed intra-and intermolecular aldol reactions L Hoang, S Bahmanyar, KN Houk, B List Journal of the American Chemical Society 125 (1), 16-17, 2003 | 543 | 2003 |
Transition states of amine-catalyzed aldol reactions involving enamine intermediates: theoretical studies of mechanism, reactivity, and stereoselectivity S Bahmanyar, KN Houk Journal of the American Chemical Society 123 (45), 11273-11283, 2001 | 463 | 2001 |
The origin of stereoselectivity in proline-catalyzed intramolecular aldol reactions S Bahmanyar, KN Houk Journal of the American Chemical Society 123 (51), 12911-12912, 2001 | 428 | 2001 |
Origins of opposite absolute stereoselectivities in proline-catalyzed direct Mannich and aldol reactions S Bahmanyar, KN Houk Organic letters 5 (8), 1249-1251, 2003 | 217 | 2003 |
Discovery of CC-930, an orally active anti-fibrotic JNK inhibitor VP Krenitsky, L Nadolny, M Delgado, L Ayala, SS Clareen, R Hilgraf, ... Bioorganic & medicinal chemistry letters 22 (3), 1433-1438, 2012 | 103 | 2012 |
Optimization of a series of triazole containing mammalian target of rapamycin (mTOR) kinase inhibitors and the discovery of CC-115 DS Mortensen, SM Perrin-Ninkovic, G Shevlin, J Elsner, J Zhao, ... Journal of medicinal chemistry 58 (14), 5599-5608, 2015 | 85 | 2015 |
Proximity effects in the Palladium-catalyzed substitution of aryl fluorides S Bahmanyar, BC Borer, YM Kim, DM Kurtz, S Yu Organic Letters 7 (6), 1011-1014, 2005 | 60 | 2005 |
The discovery of a dual TTK protein kinase/CDC2-like kinase (CLK2) inhibitor for the treatment of triple negative breast cancer initiated from a phenotypic screen JR Riggs, M Nagy, J Elsner, P Erdman, D Cashion, D Robinson, R Harris, ... Journal of medicinal chemistry 60 (21), 8989-9002, 2017 | 52 | 2017 |
Crystal structures of orotidine monophosphate decarboxylase: does the structure reveal the mechanism of nature's most proficient enzyme? KN Houk, JK Lee, DJ Tantillo, S Bahmanyar, BN Hietbrink ChemBioChem 2 (2), 113-118, 2001 | 49 | 2001 |
Aminopurine based JNK inhibitors for the prevention of ischemia reperfusion injury VP Krenitsky, M Delgado, L Nadolny, K Sahasrabudhe, L Ayala, ... Bioorganic & medicinal chemistry letters 22 (3), 1427-1432, 2012 | 33 | 2012 |
Discovery of mammalian target of rapamycin (mTOR) kinase inhibitor CC-223 DS Mortensen, SM Perrin-Ninkovic, G Shevlin, J Zhao, G Packard, ... Journal of Medicinal Chemistry 58 (13), 5323-5333, 2015 | 32 | 2015 |
Aminotriazolopyridines, compositions thereof, and methods of treatment therewith S Bahmanyar, RJ Bates, K Blease, A Calabrese, T Daniel, M Delgado, ... US Patent 8,299,056, 2012 | 32 | 2012 |
Transition states of amine-catalyzed Aldol<? index value=" aldol"?> reactions<? index value=" aldol reactions"?> involving enamine intermediates: theoretical studies of … S Bahmanyar, KN Houk J Am Chem Soc 123, 9922-3, 2001 | 32 | 2001 |
Fluorination-free synthesis of a 4, 4-difluoro-3, 3-dimethylproline derivative L Chen, YM Kim, DJ Kucera, KE Harrison, S Bahmanyar, JM Scott, ... The Journal of Organic Chemistry 71 (15), 5468-5473, 2006 | 31 | 2006 |
Substituted aminopurine compounds, compositions thereof, and methods of treatment therewith M Alexander, S Bahmanyar, J Hansen, D Huang, R Hubbard, B Jeffy, ... US Patent 9,512,124, 2016 | 26 | 2016 |
Unusual reversal of regioselectivity in antibody-mediated aldol additions with unsymmetrical methyl ketones V Maggiotti, S Bahmanyar, M Reiter, M Resmini, KN Houk, V Gouverneur Tetrahedron 60 (3), 619-632, 2004 | 24 | 2004 |
Discovery of the c-Jun N-Terminal Kinase Inhibitor CC-90001 MA Nagy, R Hilgraf, DS Mortensen, J Elsner, S Norris, J Tikhe, W Yoon, ... Journal of Medicinal Chemistry 64 (24), 18193-18208, 2021 | 20 | 2021 |
The challenges of generalizability in artificial intelligence for ADME/Tox endpoint and activity prediction DZ Huang, JC Baber, SS Bahmanyar Expert opinion on drug discovery 16 (9), 1045-1056, 2021 | 18 | 2021 |
Process Development and Scale-up of AG035029 J Saenz, M Mitchell, S Bahmanyar, N Stankovic, M Perry, B Craig-Woods, ... Organic process research & development 11 (1), 30-38, 2007 | 18 | 2007 |