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S. Bahmanyar
S. Bahmanyar
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Quantum mechanical predictions of the stereoselectivities of proline-catalyzed asymmetric intermolecular aldol reactions
S Bahmanyar, KN Houk, HJ Martin, B List
Journal of the American Chemical Society 125 (9), 2475-2479, 2003
7472003
Kinetic and stereochemical evidence for the involvement of only one proline molecule in the transition states of proline-catalyzed intra-and intermolecular aldol reactions
L Hoang, S Bahmanyar, KN Houk, B List
Journal of the American Chemical Society 125 (1), 16-17, 2003
5422003
Transition states of amine-catalyzed aldol reactions involving enamine intermediates: theoretical studies of mechanism, reactivity, and stereoselectivity
S Bahmanyar, KN Houk
Journal of the American Chemical Society 123 (45), 11273-11283, 2001
4612001
The origin of stereoselectivity in proline-catalyzed intramolecular aldol reactions
S Bahmanyar, KN Houk
Journal of the American Chemical Society 123 (51), 12911-12912, 2001
4282001
Origins of opposite absolute stereoselectivities in proline-catalyzed direct Mannich and aldol reactions
S Bahmanyar, KN Houk
Organic letters 5 (8), 1249-1251, 2003
2172003
Discovery of CC-930, an orally active anti-fibrotic JNK inhibitor
VP Krenitsky, L Nadolny, M Delgado, L Ayala, SS Clareen, R Hilgraf, ...
Bioorganic & medicinal chemistry letters 22 (3), 1433-1438, 2012
1032012
Optimization of a series of triazole containing mammalian target of rapamycin (mTOR) kinase inhibitors and the discovery of CC-115
DS Mortensen, SM Perrin-Ninkovic, G Shevlin, J Elsner, J Zhao, ...
Journal of medicinal chemistry 58 (14), 5599-5608, 2015
852015
Proximity effects in the Palladium-catalyzed substitution of aryl fluorides
S Bahmanyar, BC Borer, YM Kim, DM Kurtz, S Yu
Organic Letters 7 (6), 1011-1014, 2005
602005
The discovery of a dual TTK protein kinase/CDC2-like kinase (CLK2) inhibitor for the treatment of triple negative breast cancer initiated from a phenotypic screen
JR Riggs, M Nagy, J Elsner, P Erdman, D Cashion, D Robinson, R Harris, ...
Journal of medicinal chemistry 60 (21), 8989-9002, 2017
522017
Crystal structures of orotidine monophosphate decarboxylase: does the structure reveal the mechanism of nature's most proficient enzyme?
KN Houk, JK Lee, DJ Tantillo, S Bahmanyar, BN Hietbrink
ChemBioChem 2 (2), 113-118, 2001
492001
Aminopurine based JNK inhibitors for the prevention of ischemia reperfusion injury
VP Krenitsky, M Delgado, L Nadolny, K Sahasrabudhe, L Ayala, ...
Bioorganic & medicinal chemistry letters 22 (3), 1427-1432, 2012
332012
Discovery of mammalian target of rapamycin (mTOR) kinase inhibitor CC-223
DS Mortensen, SM Perrin-Ninkovic, G Shevlin, J Zhao, G Packard, ...
Journal of Medicinal Chemistry 58 (13), 5323-5333, 2015
322015
Aminotriazolopyridines, compositions thereof, and methods of treatment therewith
S Bahmanyar, RJ Bates, K Blease, A Calabrese, T Daniel, M Delgado, ...
US Patent 8,299,056, 2012
322012
Transition states of amine-catalyzed Aldol<? index value=" aldol"?> reactions<? index value=" aldol reactions"?> involving enamine intermediates: theoretical studies of …
S Bahmanyar, KN Houk
J Am Chem Soc 123, 9922-3, 2001
322001
Fluorination-free synthesis of a 4, 4-difluoro-3, 3-dimethylproline derivative
L Chen, YM Kim, DJ Kucera, KE Harrison, S Bahmanyar, JM Scott, ...
The Journal of Organic Chemistry 71 (15), 5468-5473, 2006
312006
Substituted aminopurine compounds, compositions thereof, and methods of treatment therewith
M Alexander, S Bahmanyar, J Hansen, D Huang, R Hubbard, B Jeffy, ...
US Patent 9,512,124, 2016
262016
Unusual reversal of regioselectivity in antibody-mediated aldol additions with unsymmetrical methyl ketones
V Maggiotti, S Bahmanyar, M Reiter, M Resmini, KN Houk, V Gouverneur
Tetrahedron 60 (3), 619-632, 2004
242004
Discovery of the c-Jun N-Terminal Kinase Inhibitor CC-90001
MA Nagy, R Hilgraf, DS Mortensen, J Elsner, S Norris, J Tikhe, W Yoon, ...
Journal of Medicinal Chemistry 64 (24), 18193-18208, 2021
202021
Process Development and Scale-up of AG035029
J Saenz, M Mitchell, S Bahmanyar, N Stankovic, M Perry, B Craig-Woods, ...
Organic process research & development 11 (1), 30-38, 2007
182007
The challenges of generalizability in artificial intelligence for ADME/Tox endpoint and activity prediction
DZ Huang, JC Baber, SS Bahmanyar
Expert opinion on drug discovery 16 (9), 1045-1056, 2021
172021
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