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Michael J. Schmeisser
Michael J. Schmeisser
Professor (Full), University Medical Centre, Johannes Gutenberg University Mainz
Bestätigte E-Mail-Adresse bei uni-mainz.de
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Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2
MJ Schmeisser, E Ey, S Wegener, J Bockmann, AV Stempel, A Kuebler, ...
Nature 486 (7402), 256-260, 2012
6742012
Meta-analysis of SHANK Mutations in Autism Spectrum Disorders: A Gradient of Severity in Cognitive Impairments
CS Leblond, C Nava, A Polge, J Gauthier, G Huguet, S Lumbroso, ...
PLoS genetics 10 (9), e1004580, 2014
6162014
Postsynaptic ProSAP/Shank scaffolds in the cross-hair of synaptopathies
AM Grabrucker, MJ Schmeisser, M Schoen, TM Boeckers
Trends in cell biology 21 (10), 594-603, 2011
2492011
Dysfunctional cerebellar Purkinje cells contribute to autism-like behaviour in Shank2-deficient mice
S Peter, MM Ten Brinke, J Stedehouder, CM Reinelt, B Wu, H Zhou, ...
Nature communications 7 (1), 12627, 2016
1882016
Zinc deficiency dysregulates the synaptic ProSAP/Shank scaffold and might contribute to autism spectrum disorders
S Grabrucker, L Jannetti, M Eckert, S Gaub, R Chhabra, S Pfaender, ...
Brain 137 (1), 137-152, 2014
1852014
Pharmacological enhancement of mGlu5 receptors rescues behavioral deficits in SHANK3 knock-out mice
C Vicidomini, L Ponzoni, D Lim, MJ Schmeisser, D Reim, N Morello, ...
Molecular psychiatry 22 (5), 689-702, 2017
1542017
IκB kinase/nuclear factor κB-dependent insulin-like growth factor 2 (Igf2) expression regulates synapse formation and spine maturation via Igf2 receptor signaling
MJ Schmeisser, B Baumann, S Johannsen, GF Vindedal, V Jensen, ...
Journal of Neuroscience 32 (16), 5688-5703, 2012
1472012
In‐depth protein profiling of the postsynaptic density from mouse hippocampus using data‐independent acquisition proteomics
U Distler, MJ Schmeisser, A Pelosi, D Reim, J Kuharev, R Weiczner, ...
Proteomics 14 (21-22), 2607-2613, 2014
1062014
Scaffold proteins at the postsynaptic density
C Verpelli, MJ Schmeisser, C Sala, TM Boeckers
Synaptic plasticity: dynamics, development and disease, 29-61, 2012
1042012
Neurobiology of autism gene products: towards pathogenesis and drug targets
KTE Kleijer, MJ Schmeisser, DD Krueger, TM Boeckers, P Scheiffele, ...
Psychopharmacology 231, 1037-1062, 2014
962014
Super-resolution microscopy reveals presynaptic localization of the ALS/FTD related protein FUS in hippocampal neurons
M Schoen, JM Reichel, M Demestre, S Putz, D Deshpande, C Proepper, ...
Frontiers in cellular neuroscience 9, 496, 2016
872016
Amyloid beta protein-induced zinc sequestration leads to synaptic loss via dysregulation of the ProSAP2/Shank3 scaffold
AM Grabrucker, MJ Schmeisser, PT Udvardi, M Arons, M Schoen, ...
Molecular neurodegeneration 6, 1-20, 2011
772011
Proteomic Analysis of Post-synaptic Density Fractions from Shank3 Mutant Mice Reveals Brain Region Specific Changes Relevant to Autism Spectrum Disorder
D Reim, U Distler, S Halbedl, C Verpelli, C Sala, J Bockmann, S Tenzer, ...
Frontiers in molecular neuroscience 10, 26, 2017
722017
The PSD protein ProSAP2/Shank3 displays synapto-nuclear shuttling which is deregulated in a schizophrenia-associated mutation
S Grabrucker, C Proepper, K Mangus, M Eckert, R Chhabra, ...
Experimental neurology 253, 126-137, 2014
702014
Phenotypic and functional analysis of SHANK3 stop mutations identified in individuals with ASD and/or ID
DM Cochoy, A Kolevzon, Y Kajiwara, M Schoen, M Pascual-Lucas, ...
Molecular autism 6, 1-13, 2015
692015
Synaptic cross-talk between N-methyl-D-aspartate receptors and LAPSER1-β-catenin at excitatory synapses
MJ Schmeisser, AM Grabrucker, J Bockmann, TM Boeckers
Journal of biological chemistry 284 (42), 29146-29157, 2009
662009
Insight on the fate of CNS-targeted nanoparticles. Part II: Intercellular neuronal cell-to-cell transport
G Tosi, A Vilella, R Chhabra, MJ Schmeisser, TM Boeckers, B Ruozi, ...
Journal of controlled release 177, 96-107, 2014
622014
An SK3 channel/nWASP/Abi-1 complex is involved in early neurogenesis
S Liebau, J Steinestel, L Linta, A Kleger, A Storch, M Schoen, K Steinestel, ...
PloS one 6 (3), e18148, 2011
562011
Shank3 is localized in axons and presynaptic specializations of developing hippocampal neurons and involved in the modulation of NMDA receptor levels at axon terminals
S Halbedl, M Schoen, MS Feiler, TM Boeckers, MJ Schmeisser
Journal of neurochemistry 137 (1), 26-32, 2016
552016
Translational neurobiology in Shank mutant mice-Model systems for neuropsychiatric disorders
MJ Schmeisser
Annals of Anatomy-Anatomischer Anzeiger 200, 115-117, 2015
472015
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